Clinical Trials

Clinical trials and studies about imaging technology can be found on this channel.

Medical researchers at Flinders University have established a new link between high body mass index (BMI) and breast cancer survival rates — with clinical data revealing worse outcomes for early breast cancer (EBC) patients and improved survival rates in advanced breast cancer (ABC).

Decoding the Effect of Body Mass Index on Breast Cancer

May 13, 2021 — Medical researchers at Flinders University have established a new link between high body mass index (BMI) ...

May 13, 2021

After radiosurgery concurrent with nivolumab in 59-year-old patient with melanoma BM (patient 1; Supplemental Tables 3 and 5), F-18 FET PET at follow-up 12 weeks after treatment initiation (bottom row) shows significant decrease of metabolic activity (TBRmean, ?28%) compared with baseline (top row), although MRI changes were consistent with progression according to iRANO criteria. Reduction of metabolic activity was associated with stable clinical course over 10 mo. CE = contrast-enhanced. Image created by

News | PET Imaging

PET Imaging Adds Valuable Information to Brain Metastasis Monitoring

May 5, 2021 — For patients with brain metastases, amino acid positron emission tomography (PET) can provide valuable ...

May 05, 2021

Using ultra-high field magnetic resonance imaging (MRI) to map the brains of people with #Down_syndrome (#DS), #researchers from #CaseWesternReserveUniversity, #ClevelandClinic, University Hospitals and other institutions detected subtle differences in the structure and function of the #hippocampus—a region of the #brain tied to memory and learning.

News | Magnetic Resonance Imaging (MRI)

Ultra-high Field MRI Detects Subtle Differences of Brain’s ‘Hippocampus’ in People with Down Syndrome

April 29, 2021 — Using ultra-high field magnetic resonance imaging (MRI) to map the brains of people with Down syndrome ...

April 29, 2021

$Overview of the scaphoid fracture detection pipeline, which consisted of a segmentation and detection convolutional neural network (CNN). A class activation map is calculated and visualized as a heatmap for fracture localization. Image courtesy of Radiological Society of North America$

News | Artificial Intelligence

Researchers Use AI to Detect Wrist Fractures

April 28, 2021 — An automated system that uses artificial intelligence (AI) is effective at detecting a common type of ...

April 28, 2021

IV contrast-enhanced 2-mSv 4-mm-thick transverse and coronal (b) CT images show inflamed diverticula (arrows), segmental colonic wall thickening, and adjacent pericolic fat stranding. Image courtesy of the American Roentgen Ray Society (ARRS), American Journal of Roentgenology (AJR)

News | Computed Tomography (CT)

Low-dose CT for Right Colonic Diverticulitis an Alternate Diagnosis of Appendicitis

April 9, 2021 — According to an open-access article in ARRS' American Journal of Roentgenology (AJR), IV contrast ...

April 09, 2021

The Moscow Center for Diagnostics and Telemedicine presented clinical research findings during ECR 2021 highlighting that full integration of AI into radiology workflow during the pandemic increased radiologists' productivity

News | Artificial Intelligence

Study Finds AI-powered COVID-19 Solution by RADlogics Reduces Turnaround Time

March 22, 2021 — Moscow Center for Diagnostics & Telemedicine and RADLogics shared the results of a large-scale study ...

March 22, 2021

WVU Rockefeller Neuroscience Institute staff prepare a patient for a first-in-the-world clinical trial to investigate the use of focused ultrasound technology to treat opioid use disorder. (WVU Photo/Brian Persinger)

News | Focused Ultrasound Therapy

West Virginia University Addresses Addiction Crisis with Novel Ultrasound Treatment

March 17, 2021 — On the heels of the country’s deadliest year for drug overdoses, the West Virginia University ...

March 17, 2021

Attending the two most recent screening appointments before a breast cancer diagnosis protects against breast cancer death, according to a Queen Mary University of London study of over half a million Swedish women conducted over 24 years

News | Breast Imaging

Attending Consecutive Mammography Screens Protects Against Breast Cancer Death

March 12, 2021 — For women who had participated in both of their previous two screening examinations, the incidence of ...

March 12, 2021

A new study by Rashi Mehta--a researcher with the WVU School of Medicine and Rockefeller Neuroscience Institute--finds that focused ultrasound may induce an immunological healing effect in the brains of Alzheimer's patients.

News | Focused Ultrasound Therapy

New Radiology Research Shows Promising Results for Focused Ultrasound Treatment of Alzheimer's

March 2, 2021 — West Virginia University scientists used magnetic resonance imaging (MRI) scans to show what happens ...

March 02, 2021

Findings indicate that PPC and GG are highly predictive of overall upstaging by PSMA PET/CT for patients with high-risk prostate cancer

News | PET-CT

Model Helps Predict Which Patients will Benefit Most from PSMA PET Scan

February 23, 2021 — A new study led by researchers at the UCLA Jonsson Comprehensive Cancer Center helps identify which ...

February 23, 2021

F-18 FES PET images of patients with ER+/PR+/HER2- invasive ductal carcinoma. Left panel: Progressive disease seen at the 8-week time-point in a patient on sequential therapy. Right panel: Stable disease through all 3 time-points, remaining on study therapy for 6.7 months until disease progression on combined vorinostat aromatase inhibitor therapy. Image created by Lanell M Peterson, Research Scientist, University of Washington Medical Oncology, Seattle WA.

News | Molecular Imaging

Molecular Imaging Determines Effectiveness of Novel Metastatic Breast Cancer Treatment

February 22, 2021 — Molecular imaging can successfully predict response to a novel treatment for ER-positive, HER2 ...

February 22, 2021

Axial FLAIR MR image shows T2 prolongation in bilateral middle cerebellar peduncles (arrows). Findings were associated with restricted diffusion and areas of T1 hypointense signal without enhancement or abnormal susceptibility. Image courtesy of American Roentgen Ray Society (ARRS), American Journal of Roentgenology (AJR)

News | Coronavirus (COVID-19)

COVID-19 Associated with Leukoencephalopathy on Brain MRI

February 22, 2021 — According to an open-access article in ARRS' American Journal of Roentgenology (AJR), COVID-19 ...

February 22, 2021

Example MR images from paediatric brain tumour patients. This first column shows T1-weighted images following the injection of gadolinium contrast agent. The second column shows T2-weighted images and the final column shows apparent diffusion coefficient maps calculated from diffusion-weighted images. (a–c) are taken from a patient with a Pilocytic Astrocytoma, (d–f) are from a patient with an Ependymoma and (g–i) were acquired from a patient with a Medulloblastoma.

News | Pediatric Imaging

Child Brain Tumors can be Classified by Advanced Imaging and AI

February 17, 2021 — Diffusion weighted imaging and machine learning can successfully classify the diagnosis and ...

February 17, 2021

T1 structural images for the two sequences, MPRAGE and MPRAGE+PMC. The top row shows the MPRAGE sequence, while the bottom row shows the images that were generated with the MPRAGE+PMC sequence. Columns represent two different participants, one with minimal head motion (left, Low-Mover) and another with a large quantity of motion (right, High-Mover). Pial and white matter (WM) surface reconstruction from Freesurfer are also shown.

News | Magnetic Resonance Imaging (MRI)

Is it Time for a Change in How Structural MRI Data is Collected?

February 17, 2021 — A new paper, "Is it time to switch your T1W sequence? Assessing the impact of prospective motion ...

February 17, 2021

Immunotherapy-based precision medicine clinical trials being developed

News | Prostate Cancer

Why Black Men's Prostate Cancer May be More Responsive to Immunotherapy

February 16, 2021 — Black men die more often of prostate cancer yet, paradoxically, have greater survival benefits from ...

February 16, 2021

The research collaboration agreement covers a joint clinical retrospective study on liver fibrosis severity in Non-Alcoholic Steato-Hepatitis (NASH) patients

News | Artificial Intelligence

Median Technologies Signs a Major Research Collaboration Agreement with UC San Diego

February 10, 2021 — Median Technologies announced the company has signed a research collaboration agreement with the ...

February 10, 2021

Unhealthy lifestyles, various diseases, stress, and aging can all contribute to an imbalance between the production of ROS and the body's ability to reduce and eliminate them. The resulting excessive levels of ROS cause "oxidative stress".

News | Magnetic Resonance Imaging (MRI)

Novel Quantum Sensor Provides New Approach to Early Diagnosis Via Imaging

February 10, 2021 — Oxygen is essential for human life, but within the body, certain biological environmental conditions ...

February 10, 2021

Phase III clinical trial of men with a clinical suspicion of prostate cancer finds MRI with targeted biopsies to be more accurate at diagnosis and less intrusive than current standard

News | Magnetic Resonance Imaging (MRI)

Using MRI for Prostate Cancer Diagnosis Equals or Beats Current Standard

February 8, 2021 — The results of a Phase III randomized clinical trial have shown that when it comes to detecting ...

February 08, 2021

A study led by UPMC Children's Hospital of Pittsburgh and the University of Pittsburgh School of Medicine shows that Black children are 18% less likely to get imaging tests as part of their emergency department visit compared to White children. Hispanic children are 13% less likely to have imaging done than Whites.

News | Pediatric Imaging

Study Shows Black or Hispanic Kids Receive Less Medical Imaging

February 3, 2021 — A study led by UPMC Children's Hospital of Pittsburgh and the University of Pittsburgh School of ...

February 03, 2021

Bright spots indicate that cancer cells have responded to a one-day challenge with estrogen in this positron emission tomography (PET) scan of a woman with breast cancer. In a small study, researchers at Washington University School of Medicine in St. Louis found that only women whose tumors responded to estrogen challenge benefited from hormone therapy. The findings could help doctors choose the treatments most likely to help their patients. Image courtesy of Farrokh Dehdashti

News | PET Imaging

Imaging Identifies Breast Cancer Patients Unlikely to Benefit from Hormone Therapy

February 3, 2021 — Hormone therapy commonly is given as a targeted treatment for women whose cancer cells carry ...

February 03, 2021