Breast Imaging

Women's health news related to breast imaging, including mammography, breast MRI, automated breast ultrasound (ABUS), breast ultrasound, breast biopsy, and positron emission mammography (PEM). This channel also includes news on breast density and the issues it causes in detecting cancers.  Mammography can be broken into two types of systems. 2-D full field digital mammography (FFDM) have almost completely replaced older X-ray film based systems. The newest generation systems use 3-D tomosynthesis mammography technology, where a series of digital images are shot in an arch around the breasts and a computer reconstructs the images into slices that can be scrolled through to see layers of tissue. This allows easier radiology reading of images, especially in women with dense breasts, because it can cancers where there are several layers of thick breast tissue that can mask cancers on 2-D mammography. Tomo is rapidly replacing FFDM.

Comparisons of high definition and standard definition infrared imaging for digital histopathology. Image courtesy of the Beckman Institute

Comparisons of high definition and standard definition infrared imaging for digital histopathology. Image courtesy of the Beckman Institute

News | Breast Imaging | April 14, 2021
Configuring Infrared Spectroscopy Tools to Better Detect Breast Cancer
April 14, 2021 — Detecting and analyzing breast cancer goes beyond the initial discovery of the cancer itself. If a...
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A 37-year-old woman developed a new, palpable left supraclavicular lymphadenopathy lump five days after her first dose of the Moderna COVID-19 vaccine in the left arm. On the day of vaccination, the patient was asymptomatic. This is an example of how the vaccine can mimic cancer and swollen lymph nodes. Image used with permission of RSNA.

A 37-year-old woman developed a new, palpable left supraclavicular lymphadenopathy lump five days after her first dose of the Moderna COVID-19 vaccine in the left arm. On the day of vaccination, the patient was asymptomatic. This is an example of how the vaccine can mimic cancer and swollen lymph nodes. Read more about this case study. Image used with permission of RSNA.

Feature | Coronavirus (COVID-19) | April 09, 2021 | By Dave Fornell, Editor
COVID-19 Vaccine Can Cause False Positive Cancer Diagnosis
While the mass COVID-19 vaccination effort over the past four months is bringing closer the light at the end of the...
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3-D mammography reduces the number of breast cancer cases diagnosed in the period between routine screenings, when compared with traditional mammography, according to a large study from Lund University in Sweden. The results are published in the journal Radiology.

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News | Breast Imaging | April 09, 2021
Fewer Breast Cancer Cases Between Screening Rounds with 3-D Mammography
April 9, 2021 — 3-D mammography reduces the number of breast cancer cases diagnosed in the period between routine...
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Mobidiag Oy, a privately held, commercial-stage Finnish-French developer of innovative molecular diagnostic tests and instrumentation, announced today that it has signed a definitive agreement to be acquired by Hologic, Inc., a global leader in women's health, for an enterprise value of approximately $795 million.  This includes a cash payment of approximately $714 million for Mobidiag’s equity, and net debt of approximately $81 million.
News | Women's Health | April 08, 2021
Mobidiag to be Acquired by Hologic for $795M
April 8, 2021 — Mobidiag Oy, a privately held, commercial-stage Finnish-French developer of innovative molecular...
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Ultrasound is an invaluable diagnostic tool for the early detection of breast cancer, but the classification of lesions is sometimes challenging and time consuming. Could artificial intelligence hold the answer to solving these problems? Graphic courtesy of Chinese Medical Journal

Ultrasound is an invaluable diagnostic tool for the early detection of breast cancer, but the classification of lesions is sometimes challenging and time consuming. Could artificial intelligence hold the answer to solving these problems? Graphic courtesy of Chinese Medical Journal

News | Artificial Intelligence | April 06, 2021
Artificial Intelligence Improves Accuracy of Breast Ultrasound Diagnoses
April 6, 2021 — In 2020, the International Agency for Research on Cancer of the World Health Organization stated that...
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 iCAD, Inc. announced that ProFound AI for 2D Mammography might notably reduce the risk of interval breast cancer, according to a retrospective analysis recently published in the Journal of Medical Screening. 
News | Breast Imaging | April 02, 2021
New Research Indicates ProFound AI May Reduce Interval Breast Cancer Rates
April 2, 2021 — iCAD, Inc. announced that ProFound AI for 2D Mammography might notably reduce the risk of interval...
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While the COVID-19 crisis is challenging, the pandemic is also giving researchers an opportunity to discover new approaches to saving lives. A study published in the JAMA Network Open on Thursday, March 25, 2021, recommends a new way for triaging mammogram patients during times of limited capacity, such as pandemic surges, when individuals may also experience anxiety about COVID-19.

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News | Breast Imaging | April 01, 2021
Catching More Breast Cancers When Mammograms are Limited
April 1, 2021 — While the COVID-19 crisis is challenging, the pandemic is also giving researchers an opportunity to...
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In looking at the broader impact of the COVID-19 pandemic on health and wellbeing, public health experts are examining screening rates for cancer. A new study looking at U.S. mammography screening rates during the first five months of the pandemic found both a strong rebound in breast cancer screening rates and a concerning cumulative deficit in mammograms due to missed appointments, as well as uncovering disparities when looking at screening according to race

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News | Breast Imaging | April 01, 2021
National Study Examines US Mammography Screening Rates During Epidemic
April 1, 2021 — In looking at the broader impact of the COVID-19 pandemic on health and wellbeing, public health...
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Videos | Breast Imaging | March 26, 2021
VIDEO: COVID Vaccine May Cause Enlarged Lymph Nodes on Mammograms
Constance "Connie" Lehman, M.D., Ph.D., chief of breast imaging, co-director of the Avon Comprehensive Breast...
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iCad announced that ProFound AI Version 3.0 for Digital Breast Tomosynthesis (DBT) was cleared by the U.S. Food and Drug Administration (FDA).
News | Breast Imaging | March 23, 2021
FDA Clears for ProFound AI Version 3.0 for 3D Mammography
March 23, 2021 — iCad announced that ProFound AI Version 3.0 for Digital Breast Tomosynthesis (DBT) was cleared by the...
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Detection of tumor-infiltrating lymphocytes (TILs) using explainable AI. The AI-technique is used to generate a heatmap showing TILs (red) and other tissues and cells (blue and green). Image courtesy of Klauschen/Charité

Detection of tumor-infiltrating lymphocytes (TILs) using explainable AI. The AI-technique is used to generate a heatmap showing TILs (red) and other tissues and cells (blue and green). Image courtesy of Klauschen/Charité

News | Artificial Intelligence | March 22, 2021
Making the Role of AI in Breast Cancer Explainable
March 22, 2021 — Researchers at Charité - Universitätsmedizin Berlin and TU Berlin as well as the University of Oslo...
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Left to right: Subtraction right mediolateral oblique (MLO) CEM was non-diagnostic because of artifact, potentially due to motion misregistration from extended exposure time; subtraction right MLO implant displaced CEM image shows 5.8 cm enhancing mass (arrow); contrast-enhanced MRI sagittal subtraction image shows concordant mass (arrow).

Left to right: Subtraction right mediolateral oblique (MLO) CEM was non-diagnostic because of artifact, potentially due to motion misregistration from extended exposure time; subtraction right MLO implant displaced CEM image shows 5.8 cm enhancing mass (arrow); contrast-enhanced MRI sagittal subtraction image shows concordant mass (arrow).

News | Breast Imaging | March 18, 2021
Contrast-Enhanced Mammography for Breast Cancer in Women With Augmented Breasts
March 18, 2021 — According to ARRS’ American Journal of Roentgenology (AJR), contrast-enhanced mammography (CEM) showed...
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Attending the two most recent screening appointments before a breast cancer diagnosis protects against breast cancer death, according to a Queen Mary University of London study of over half a million Swedish women conducted over 24 years

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News | Breast Imaging | March 12, 2021
Attending Consecutive Mammography Screens Protects Against Breast Cancer Death
March 12, 2021 — For women who had participated in both of their previous two screening examinations, the incidence of...
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Breast cancer is the most common fatal cancer in women. Early detection increases a woman's chances of recovery. Magnetic Resonance Imaging (MRI) is an accurate technique for detecting and classifying tumors in breast tissue.
News | MRI Breast | March 09, 2021
Simple MRI Measurement Could Avoid 30% of Breast Biopsies
March 9, 2021 — Breast cancer is the most common fatal cancer in women. Early detection increases a woman's chances of...
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A comparison of standard mammography imaging (left) in a woman with dense breasts and a breast MRI imaging study (right) showing a clearly defined cancer and is extremely hard to detect on the mammograms.

A comparison of standard mammography imaging (left) in a woman with dense breasts and a breast MRI imaging study (right) showing a clearly defined cancer and is extremely hard to detect on the mammograms. Images from Christiane Kuhl, M.D.

Feature | MRI Breast | March 04, 2021 | By Dave Fornell, Editor
Use of Breast MRI Screening in Women With Dense Breasts
Dense breast tissue can hide cancers in mammograms in about half of women. Supplemental imaging is often needed to...
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Researchers said women who skip even one scheduled mammography screening before a breast cancer diagnosis face a significantly higher risk of dying from the cancer.

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News | Mammography | March 03, 2021
Skipping Mammogram Increases Risk of Death from Breast Cancer
March 3, 2021 — Attendance at regular mammography screening substantially reduces the risk of dying from breast cancer...
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55-year-old woman who underwent screening mammogram and ultrasound 7 days after first COVID-19 vaccination dose. Screening mammogram and US demonstrated unilateral left axillary lymph node with cortical thickness of 5 mm on ultrasound (not shown). BI-RADS category 0 was assigned. Ultrasound from diagnostic work-up performed 7 days later showed no change in lymph node size. BI-RADS 3 was assigned. #COVIDvaccine #COVID19

55-year-old woman who underwent screening mammogram and ultrasound 7 days after first COVID-19 vaccination dose. Screening mammogram and US demonstrated unilateral left axillary lymph node with cortical thickness of 5 mm on ultrasound (not shown). BI-RADS category 0 was assigned. Ultrasound from diagnostic work-up performed 7 days later showed no change in lymph node size. BI-RADS 3 was assigned.

News | Breast Imaging | February 24, 2021
COVID-19 Vaccination Axillary Adenopathy Detected During Breast Imaging
February 24, 2021 — An open-access article in ARRS’ American Journal of Roentgenology (AJR) describes the clinical and...
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Breast Cancer Index added to National Comprehensive Cancer Network guidelines to predict benefit from extended endocrine therapy
News | Women's Health | February 23, 2021
Hologic Completes Acquisition of Biotheranostics, Enabling Entry into Growing Oncology Market
February 23, 2021 — Hologic, Inc. has completed its previously announced acquisition of molecular oncology leader...
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F-18 FES PET images of patients with ER+/PR+/HER2- invasive ductal carcinoma. Left panel: Progressive disease seen at the 8-week time-point in a patient on sequential therapy. Right panel: Stable disease through all 3 time-points, remaining on study therapy for 6.7 months until disease progression on combined vorinostat aromatase inhibitor therapy. Image created by Lanell M Peterson, Research Scientist, University of Washington Medical Oncology, Seattle WA.

F-18 FES PET images of patients with ER+/PR+/HER2- invasive ductal carcinoma. Left panel: Progressive disease seen at the 8-week time-point in a patient on sequential therapy. Right panel: Stable disease through all 3 time-points, remaining on study therapy for 6.7 months until disease progression on combined vorinostat aromatase inhibitor therapy. Image created by Lanell M Peterson, Research Scientist, University of Washington Medical Oncology, Seattle WA.

News | Molecular Imaging | February 22, 2021
Molecular Imaging Determines Effectiveness of Novel Metastatic Breast Cancer Treatment
February 22, 2021 — Molecular imaging can successfully predict response to a novel treatment for ER-positive, HER2-...
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Examples of the imaging performance of XPCI-CT (b,e) compared to conventional specimen radiography (a,d) and benchmarked against histopathology (c,f). he top row focuses on the similarity between the XPCI-CT slice in (b) and the histological slice in (c). Arrow 1 indicates margin involvement, arrow 2 a variation in density in the internal structure of the tumour mass, arrow 3 tumour-induced inflammation. All this is confirmed by the histological slice in (c), and hardly visible in the conventional image in

Examples of the imaging performance of XPCI-CT (b,e) compared to conventional specimen radiography (a,d) and benchmarked against histopathology (c,f). he top row focuses on the similarity between the XPCI-CT slice in (b) and the histological slice in (c). Arrow 1 indicates margin involvement, arrow 2 a variation in density in the internal structure of the tumour mass, arrow 3 tumour-induced inflammation. All this is confirmed by the histological slice in (c), and hardly visible in the conventional image in (a). The bottom row focuses on the detection of small calcifications, a key feature in DCIS. These are undetectable in (d), detected in (e), enhanced in the maximum intensity projection (MIP) image at the bottom of (f), and confirmed by histopathology in the top part of (f). The scale bar [shown in (b) and (e)] is the same for all images apart from (f), which has its own scale. Red arrows in (e) and (f) indicate the microcalcifications. Image courtesy of Professor Alessandro Olivo

News | Breast Imaging | February 22, 2021
Advances in X-ray Imaging can Help Patients with Breast Cancer
February 22, 2021 — A new X-ray imaging scanner to help surgeons performing breast tumor removal surgery has been...
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