Clinical Trials

Clinical trials and studies about imaging technology can be found on this channel.

"Residual Echo" of Ancient Humans May Hold Clues to Mental Disorders

MRI data shows (left) areas of the skull preferentially affected by the amount of Neanderthal-derived DNA and (right) areas of the brain’s visual system in which Neanderthal gene variants influenced cortex folding (red) and gray matter volume (yellow). Image courtesy of Michael Gregory, M.D., NIMH Section on Integrative Neuroimaging

News | Neuro Imaging | July 26, 2017

July 26, 2017 — Researchers from the National Institute of Mental Health (NIMH) have produced the first direct...

New York Hospital Finds Significant Cost Savings With Toshiba’s Aquilion One CT
News | Computed Tomography (CT) | July 25, 2017

July 25, 2017 — In five years, Kaleida Health’s Stroke Care Center (SCC) at the Gates Vascular Institute in Buffalo...

New PET-CT Scan Improves Detection in Rare Cardiac Condition
News | PET-CT | July 25, 2017

July 25, 2017 — Using a new nuclear...

Radiotherapy Prior to Surgery Reduces Secondary Tumor Risk in Early-Stage Breast Cancer Patients
News | Radiation Therapy | July 24, 2017

July 24, 2017 — Moffitt Cancer Center researchers launched a first-of-its-kind study comparing the long-term...

Electronic Brachytherapy Comparable to Mohs Surgery in Early-Stage Non-Melanoma Skin Cancer Treatment
News | Brachytherapy Systems | July 20, 2017

July 20, 2017 — Rates of recurrence in early-stage non-melanoma skin cancer (NMSC) patients were virtually identical...

3-D Vascular Ultrasound Quantifies Plaque Burden to Estimate Cardiovascular Risk
News | Cardiovascular Ultrasound | July 20, 2017

July 20, 2017 — In a large, first-of-its-kind population, researchers found an experimental technique known as...

Low Doses of Radiation Could Harm Cardiovascular Health
News | Radiation Dose Management | July 17, 2017

July 17, 2017 — Ionizing radiation, such as X-rays, has a harmful effect on the cardiovascular system even at doses...

PET/CT Tracer Identifies Vulnerable Lesions in Non-Small Cell Lung Cancer Patients

Example of a patient with an upper left lung NSCLC: A: FDG; B: FDG PET/CT; C: Planning radiotherapy based on FDG (66Gy) with BTVm (GTV), CTV and PTV; D: PET FMISO E: FMISO PET/CT; F: boost based on the FMISO PET (76Gy) with BTVh (biological hypoxic target volume) and PTV boost. Credit: QuantIF – LITIS EA 4108 – FR CNRS 3638, Henri Becquerel Cancer Center, Rouen, France

News | PET-CT | July 14, 2017

July 14, 2017 — Fluorine-18 (18F)-fluoromisonidazole (FMISO) is a positron emission tomography (PET)...

Insurance Coverage for CT Colonography Increases Likelihood of Screening
News | Colonoscopy Systems | July 12, 2017

July 12, 2017 — People with insurance policies that cover...

Researchers Identify Visual System Changes that May Signal Parkinson's Disease
News | Neuro Imaging | July 11, 2017

July 11, 2017 — Changes in the visual systems of newly diagnosed Parkinson’s disease patients may provide important...

New Study Uses MRI to Probe Psychopathic Brains
News | Neuro Imaging | July 07, 2017

July 7, 2017 — Josh Buckholtz, Ph.D., associate professor of psychology at Harvard University, is the senior author...

Surgery and High-Dose SBRT Radiation Can Be Combined to Treat Kidney Cancer
News | Stereotactic Body Radiation Therapy (SBRT) | July 05, 2017

July 5, 2017 — A new study from Roswell Park Cancer Institute reporting the findings of the first clinical trial to...

New Study Highlights Breakthrough Therapy to Reduce Mammographic Breast Density
News | Breast Density | June 28, 2017

June 26, 2017 — Stephen N. Birrell, M.D., Ph.D., presented breakthrough findings into the reduction of mammographic...

NCCN Guidelines for Chest CT in Breast Cancer Reduce False Positives, Healthcare Spending
News | Breast Imaging | June 26, 2017

June 26, 2017 — A recent study appears to confirm the recommendations of the National Comprehensive Cancer Network (...

MRI Plus Mammography Improves Detection of New Breast Cancer After Surgery
News | Breast Imaging | June 22, 2017

June 22, 2017 — A new article published by ...

Dual-Agent PET/MR With Time of Flight Detects More Cancer

Tc-99m MDP bone scan (left) is negative for osseous lesions. NaF/FDG PET/MRI (right and second slide) confirms absence of bone metastases, but shows liver metastases. Image courtesy of Stanford University.

News | PET-MRI | June 20, 2017

June 20, 2017 — Simultaneous injections of the radiopharmaceuticals fluorine-18 fluorodeoxyglucose (18F-FDG) and 18F...

Combined Optical and Molecular Imaging Could Guide Breast-Conserving Surgery

WLE specimen from a patient with a grade 3, ER-/HER2-, no special type (NST) carcinoma. (A) Cerenkov image; (B) Grey-scale photographic image overlaid with Cerenkov signal. An increased signal from the tumor is visible (white arrows); mean radiance is 871 ± 131 photons/s/cm2/sr, mean TBR is 3.22. Both surgeons measured the posterior margin (outlined in blue) as 2 mm (small arrow); a cavity shaving would have been performed if the image had been available intraoperatively. The medial margin (outlined in green) measured >5 mm by both surgeons. Pathology ink prevented assessing the lateral margin; a phosphorescent signal is visible (open arrows). (C) Specimen radiography image. The absence of one surgical clip to mark the anterior margin, and the odd position of the superior margin clip (white arrow) prevented reliable margin assessment. (D) Combined histopathology image from two adjacent pathology slides on which the posterior margin (bottom of image) and part of the primary tumor are visible (open arrows). The distance from the posterior margin measured 3 mm microscopically (double arrow). The medial margin is > 5 mm (not present in image). Credit: A. D. Purushotham, M.D., King’s College London, UK

News | Nuclear Imaging | June 20, 2017

June 20, 2017 — Breast-conserving surgery (BCS) is the primary treatment for early-stage...

pediatric imaging
News | Pediatric Imaging | June 14, 2017

Despite evidence showing that the routine use of sonography...

elderly women_iStock
News | Clinical Trials | June 09, 2017

The milestone Imaging Dementia — Evidence for Amyloid Scanning (IDEAS) Study is working with government and academic...

OCM images

These are sample OCM images (first row) and corresponding histology images (second row) of human breast tissue. The ground truth labels for the tissue type of these images are: (a) carcinoma, (b) lobule, (c) stroma, (d) adipose. Image courtesy of Sunhua Wan, Hsiang-Chieh Lee, Xiaolei Huang, Ting Xu, Tao Xu, Xianxu Zeng, Zhan Zhang, Yuri Sheikine, James L. Connolly, James G. Fujimoto, Chao Zhou

News | Clinical Trials | June 07, 2017

According to a ...