Clinical Trials

Clinical trials and studies about imaging technology can be found on this channel.

The cartilage in this MRI scan of a knee is colorized to show greater contrast between shades of gray.

The cartilage in this MRI scan of a knee is colorized to show greater contrast between shades of gray. Image courtesy of Kundu et al. (2020) PNAS

News | Artificial Intelligence | September 22, 2020
September 22, 2020 — Researchers at the University of Pittsburgh School of Medicine and Carnegie Mellon University...
New research from King's College London has found that COVID-19 may be diagnosed on the same emergency scans intended to diagnose stroke.

Canon Medical Systems

News | Cardiac Imaging | September 22, 2020
September 22, 2020 — New research from King's College London has found that COVID-19 may be diagnosed on the same...
Ultrasound-guided carpal tunnel release quickly improves hand function and reduces hand discomfort, making the procedure a safe, effective, and less invasive alternative to traditional open or endoscopic surgery

Patients answered three questionnaires (Quick-Disabilities of the Arm, Shoulder, and Hand [QDASH] and two parts of the Boston Carpal Tunnel Syndrome Questionnaire: symptom severity [BCTSQ-SS] and functional status [BCTSQ-FS] scales) assessing the affected wrist's function and discomfort immediately pre-procedure, 2 weeks post-procedure, and at least one year post-procedure. Infographic courtesy of the American Roentgen Ray Society (ARRS), American Journal of Roentgenology (AJR)

News | Ultrasound Imaging | September 17, 2020
September 17, 2020 — According to ARRS' American Journal of Roentgenology (AJR), ultrasound-guided carpal tunnel...
HABLE study prioritizes brain imaging and biomarker research among Mexican Americans.

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News | PET Imaging | September 14, 2020
September 14, 2020 — To meet the pressing need to better understand the prevalence, progression, and clinical impact of...
Six months after deployment, the no-show rate of the predictive model was 15.9%, compared with 19.3% in the preceding 12-month preintervention period — corresponding to a 17.2% improvement from the baseline no-show rate (p < 0.0001). The no-show rates of contactable and noncontactable patients in the group at high risk of appointment no-shows as predicted by the model were 17.5% and 40.3%, respectively (p < 0.0001).

Weekly outpatient MRI appointment no-show rates for 1 year before (19.3%) and 6 months after (15.9%) implementation of intervention measures in March 2019, as guided by XGBoost prediction model. Squares denote data points. Courtesy of the  American Roentgen Ray Society (ARRS), American Journal of Roentgenology (AJR)

News | Artificial Intelligence | September 10, 2020
September 10, 2020 — According to ARRS’ American Journal of Roentgenology (AJR), artificial intelligence (AI)...
UT Dallas study aims to advance thermography for monitoring tumors

Adolfo Lozano, PhD'20, works on a proof-of-concept computer model of the thermal properties of breast cancer. He and other UT Dallas researchers aim to improve digital thermal imaging as a tool for monitoring cancer and its treatment. Image courtesy of The University of Texas at Dallas

News | Breast Imaging | September 09, 2020
September 9, 2020 — Thermal imaging has been available for decades to detect temperature differences on the skin that...
High-intensity focused ultrasound (HIFU), a technology used to treat localized prostate cancer, has shown adequate control of prostate cancer while avoiding major side effects of surgery or radiation therapy, according to a new study in The Journal of Urology, Official Journal of the American Urological Association

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News | Prostate Cancer | September 08, 2020
September 8, 2020 — Approved by the US Food and Drug Administration (FDA) in 2015 for prostate tissue ablation, the...
A researcher holds a flexible X-ray scintillator developed by Professor Biwu Ma and his research team. The team has developed a new material that could be used to make flexible X-ray detectors that are less harmful to the environment and cost less than existing technologies. Photo courtesy of Biwu Ma / Florida State University

A researcher holds a flexible X-ray scintillator developed by Professor Biwu Ma and his research team. The team has developed a new material that could be used to make flexible X-ray detectors that are less harmful to the environment and cost less than existing technologies. Photo courtesy of Biwu Ma / Florida State University

News | X-Ray | September 03, 2020
September 3, 2020 — Florida State University researchers have developed a new material that could be used to make...
B, Representative computational model shows lung stroma intraorgan structure of XCAT phantom that was developed using anatomically informed mathematic model. Inset shows enlarged view for better visibility of details and small structures. C, Voxelized rendition (ground truth) of XCAT phantom highlights detailed model of lung parenchyma. Inset shows enlarged view for better visibility of details and small structures

B, Representative computational model shows lung stroma intraorgan structure of XCAT phantom that was developed using anatomically informed mathematic model. Inset shows enlarged view for better visibility of details and small structures. C, Voxelized rendition (ground truth) of XCAT phantom highlights detailed model of lung parenchyma. Inset shows enlarged view for better visibility of details and small structures. Image courtesy of the American Roentgen Ray Society (ARRS), American Journal of Roentgenology (AJR)

News | Coronavirus (COVID-19) | August 26, 2020
August 26, 2020 — An open-access article in ARRS' American Journal of Roentgenology (AJR) established a foundation for...
Public health screening guidelines for lung cancer followed by the United States Preventive Services Task Force (USPSTF) and the Center for Medicare and Medicaid Services (CMS) undercount African Americans, contributing to disparities in lung cancer screening and treatment, according to a study published today in the Journal of Thoracic Oncology.

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News | Lung Imaging | August 19, 2020
August 19, 2020 — Public health screening guidelines for lung cancer followed by the United States Preventive Services...

An oncologist practices social distancing while talking to a cancer patient. Image courtesy of University of Michigan Rogel Cancer Center

News | Coronavirus (COVID-19) | August 07, 2020
August 7, 2020 — When COVID-19 struck, health care pivoted hard. Any unnecessary procedures or appointments were...
As part of an international collaboration, researchers from Aarhus University and University of Leicester have succeeded in developing a dynamic 3-D CT scanning method that shows what happens inside the body during simulated heart massage

A look inside cardiopulmonary resuscitation: A 4-D computed tomography model of simulated closed chest compression. A proof of concept. Courtesy of Kasper Hansen/Jonathan Bjerg Moeller/Aarhus University

News | Cardiac Imaging | August 07, 2020
August 7, 2020 — Rapid first aid during cardiac arrest makes the difference between life and death. But what happens to...
Ghost imaging approach could enable detailed movies of the heart with low-dose X-rays

Researchers developed a high-resolution X-ray imaging technique based on ghost imaging that can capture the motion of rapidly moving objects. They used it to create a movie of a blade rotating at 100,000 frames per second. Image courtesy of Sharon Shwartz, Bar-Ilan University

News | X-Ray | August 06, 2020
August 6, 2020 — Researchers have demonstrated a new high-resolution X-ray imaging technique that can capture the...
 AG Mednet, a technology company streamlining, automating and increasing data quality for clinical trials, announces significant expansion to its Submission Quality and Compliance (SQC) Toolkit. The Judi-based integrated image quality control (QC) product functionality gives core laboratories, CROs and sponsors the most complete and powerful capability to manage site image submissions in record time.
News | Information Technology | July 29, 2020
July 29, 2020 — AG Mednet, a technology company streamlining, automating and increasing data quality for clinical...
Prostate biopsy with cancer probability (blue is low, red is high). This case was originally diagnosed as benign but changed to cancer upon further review. The AI accurately detected cancer in this tricky case. Image courtesy of Ibex Medical Analytics

Prostate biopsy with cancer probability (blue is low, red is high). This case was originally diagnosed as benign but changed to cancer upon further review. The AI accurately detected cancer in this tricky case. Image courtesy of Ibex Medical Analytics

News | Prostate Cancer | July 28, 2020
July 28, 2020 — A study published in The Lancet Digital Health by UPMC and University of Pittsburgh researchers...
(a) A schematic of cycloidal computed tomography (not to scale, seen from top); by adding an array of beam stops in front of the detector, the setup is transformed into an edge-illumination x-ray phase-contrast imaging device. (b) A sinogram sampling grid for a rotation-only scheme. (c) A sinogram sampling grid for a cycloidal scheme. The grids are shown for one mask period and a subset of rotation angles; the combination of empty and filled circles shows the grids that would be achieved through fine latera

(a) A schematic of cycloidal computed tomography (not to scale, seen from top); by adding an array of beam stops in front of the detector, the setup is transformed into an edge-illumination x-ray phase-contrast imaging device. (b) A sinogram sampling grid for a rotation-only scheme. (c) A sinogram sampling grid for a cycloidal scheme. The grids are shown for one mask period and a subset of rotation angles; the combination of empty and filled circles shows the grids that would be achieved through fine lateral sampling (requiring dithering); the filled circles show the data that are sampled without dithering.

News | Computed Tomography (CT) | July 24, 2020
July 24, 2020 — A computed tomography (CT) scan technique that splits a full X-ray beam into thin beamlets can deliver...
Medical professionals around the world have been feeding lung X-rays into a database since the beginning of the pandemic

Pre-processing results. Image courtesy of Applied Sciences.

News | Coronavirus (COVID-19) | July 22, 2020
July 22, 2020 — Researchers from the Department of Computer Architecture and Technology at the University of Seville's...
Pioneering study, which included humans, led by Tel Aviv University researchers contradicts widespread conjectures
News | Magnetic Resonance Imaging (MRI) | July 21, 2020
July 21, 2020 — Researchers at Tel Aviv University, led by Prof. Yaniv Assaf of the School of Neurobiology,...

Fig. 1 The basis of high-sensitivity SPION imaging at ultra-low magnetic fields.

(A) Magnetization of 25-nm SPIONs (green), gadolinium CA (Gd-DTPA/Magnevist, blue), and water (red) as a function of magnetic field strength (B0). (B) Magnetization as a function of magnetic field strength (B0) in the ULF (<10 mT) regime for the materials shown in (A). Superparamagnetic materials, such as SPIONs, are highly magnetized even at ULF. Paramagnetic materials, such as CAs based on gadolinium, and body tissues (which typically have diamagnetic susceptibilities close to water) have absolute magnetizations that increase linearly with field strength. Curves in (A) and (B) were reproduced from data in (3253) and reflect the magnetic moment per kilogram of compound. (C) Highly magnetized SPIONs (brown) interact with nearby 1H spins in water, shortening 1H relaxation times, and causing susceptibility-based shifts in Larmor frequency. Image courtesy of Science Advances

News | Magnetic Resonance Imaging (MRI) | July 20, 2020
July 20, 2020 — Lowering the cost of magnetic-resonance imaging (MRI) could revolutionize how doctors diagnose and...
PET/CT imaging showing uptake and retention of 86Y-NM600 (imaging agent) in immunocompetent mice bearing prostate tumors. PET imaging data was employed to estimate tumor dosimetry and prescribe an immunomodulatory 90Y-NM600 (therapy agent) injected activity. Image courtesy of R Hernandez et al., University of Wisconsin-Madison, WI.

PET/CT imaging showing uptake and retention of 86Y-NM600 (imaging agent) in immunocompetent mice bearing prostate tumors. PET imaging data was employed to estimate tumor dosimetry and prescribe an immunomodulatory 90Y-NM600 (therapy agent) injected activity. Image courtesy of R Hernandez et al., University of Wisconsin-Madison, WI.

News | PET-CT | July 15, 2020
July 15, 2020 — Targeted radionuclide therapy has been found to create a favorable tumor microenvironment in prostate...