PET Imaging

Positron emission tomography (PET) is a nuclear imaging technology (also referred to as molecular imaging) that enables visualization of metabolic processes in the body. The basics of PET imaging is that the technique detects pairs of gamma rays emitted indirectly by a positron-emitting radionuclide (also called radiopharmaceuticals, radionuclides or radiotracer). The tracer is injected into a vein on a biologically active molecule, usually a sugar that is used for cellular energy. PET systems have sensitive detector panels to capture gamma ray emissions from inside the body and use software to plot to triangulate the source of the emissions, creating 3-D computed tomography images of the tracer concentrations within the body.

David Schultz, M.D., Ph.D.

David Schultz, M.D., Ph.D.

News | PET-MRI | November 08, 2018
The Radiological Society of North America (RSNA) Research & Education (R&E) Foundation awarded the 2018 Hitachi...

PET images taken on Philips’ Vereos PET/CT at Methodist Hospital in Omaha, Neb., show a lung lesion. Caveat: Because results may vary, “results from case studies are not predictive of results in other cases,” Philips cautioned. Images courtesy of Omaha’s Methodist Hospital

Sponsored Content | Blog | PET Imaging | November 07, 2018
Precision can have an enormous impact on patients. From diagnosis to patient monitoring (see “How Digital PET/CT Can...
Feature | PET Imaging | November 07, 2018 | By Greg Freiherr
Positron emission tomography (PET) is getting ready to venture outside oncology, cardiology and mainstream neurology....
Sponsored Content | Podcast | PET Imaging | November 07, 2018
PET is getting ready to venture outside oncology, cardiology and mainstream neurology. High on the list of new clinical...
Staging F-18 FDG PET/CT images of adenocarcinoma in the RUL of the lung illustrates the value of Vereos. The primary lesion in the right upper lobe appears in the upper row (PET image is left, CT image is right). A 3 mm synchronous primary or metastatic lesion in the RUL is apparent in the lower row. The precision afforded by Vereos' images provided the basis for the patient to undergo RUL lobectomy instead of thermal ablation of the primary lesion. Images courtesy of Dr. Jay Kikut and UVM

Staging F18FDG PET/CT images of adenocarcinoma in the RUL (right upper lobe) of the lung illustrates the value of Vereos. The primary lesion in the right upper lobe appears in the upper row (PET image is left, CT image is right). A 3 mm synchronous primary or metastatic lesion in the RUL is apparent in the lower row. The precision afforded by Vereos' images provided the basis for the patient to undergo RUL lobectomy instead of thermal ablation of the primary lesion. (Images courtesy of Dr. Jay Kikut and UVMC)

Sponsored Content | Blog | PET-CT | October 25, 2018
Efficiency and effectiveness are inseparable in clinical medicine. Digital PET addresses them both. The key is the...
PET Imaging Offers New Possibilities in Chronic Liver Disease Management

Hepatic 18F-FDG, 18F-FAC, and 18F-DFA accumulation are affected in a mouse model of autoimmune hepatitis. (A) Histochemical and immunohistochemical analyses of liver sections from vehicle- and ConA-treated mice. Scale bars represent 50 microns. Transverse PET/CT images (B) and quantification (C) of vehicle- and ConA-treated mice injected with 18F-FDG, 18F-FAC, and 18FDFA. Livers are outlined in a white dotted line. Quantification represents radiotracer accumulation in the liver normalized to a background organ. Image courtesy of Salas J.R., Chen B.Y., Wong A., et al.

News | PET Imaging | October 24, 2018
October 24, 2018 — While liver biopsies are powerful and reliable, they are also invasive, painful, limited and subject...
Each digital photon counter in the Vereos PET/CT detector contains thousands of solid-state sensors that digitally count individual photons.

Each digital photon counter in the Vereos PET/CT detector contains thousands of solid-state sensors that digitally count individual photons.

Sponsored Content | Blog | PET-CT | October 17, 2018
Analog is approximate. Digital is specific. Therein lies the fundamental difference between digital PET and its analog...
Huntsman Cancer Institute Installs First Preclinical nanoScan 3T PET/MRI in U.S.
News | PET-MRI | October 10, 2018
October 10, 2018 — The Center for Quantitative Cancer Imaging at Huntsman Cancer Institute (HCI) at the University of...
Digital PET/CT, achieved using Vereos from Philips Healthcare, can spot even a small lesion (arrow). Image courtesy of Brian Gordon, M.D.

Digital PET/CT, achieved using Vereos from Philips Healthcare, can spot even a small lesion (arrow). Image courtesy of Brian Gordon, M.D.

Sponsored Content | Blog | PET-CT | October 08, 2018
PET/CT can be indispensible as a diagnostic and prognostic tool; in the assessment of patient response to therapy and...
Technology and Radionucleotide Development Will Fuel Mobile Gamma Camera Adoption
News | Nuclear Imaging | September 27, 2018
September 27, 2018 — Advancements in healthcare technology, particularly in the surgery category, have led to an...
Bruker Introduces New High-Performance Preclinical PET/CT Si78 System
Technology | PET-CT | September 26, 2018
September 26, 2018 — Bruker recently announced the introduction of the new preclinical PET/CT Si78 scanner for whole-...
PET Imaging Agent Predicts Brain Tau Pathology, Alzheimer's Diagnosis
News | PET Imaging | September 05, 2018
September 5, 2018 — Eli Lilly and Co. and Avid Radiopharmaceuticals Inc. announced a Phase 3 study of positron emission...
Abnormal Protein Concentrations Found in Brains of Military Personnel With Suspected CTE

Researchers are using the tracer, which is injected into a patient, then seen with a PET scan, to see if it is possible to diagnose chronic traumatic encephalopathy in living patients. In this image, warmer colors indicate a higher concentration of the tracer, which binds to abnormal proteins in the brain. Credit UCLA Health.

News | PET Imaging | August 24, 2018
August 24, 2018 — In a small study of military personnel who had suffered head trauma and had reported memory and mood...
PET Tracer Identifies Estrogen Receptor Expression Differences in Breast Cancer Patients
News | PET Imaging | August 09, 2018
August 9, 2018 — In metastatic breast cancer, prognosis and treatment is largely influenced by estrogen receptor (ER)...
Novel PET Imaging Method Could Track and Guide Type 1 Diabetes Therapy
News | PET Imaging | August 03, 2018
August 3, 2018 — Researchers have discovered a new nuclear medicine test that could improve care of patients with type...
Researchers Trace Parkinson’s Damage in the Heart
News | PET Imaging | July 17, 2018
July 17, 2018 — A new way to examine stress and inflammation in the heart will help Parkinson’s researchers test new...
Siemens Healthineers Announces FDA Clearance of syngo.via VB30 Molecular Imaging Software
Technology | Nuclear Imaging | July 16, 2018
July 16, 2018 — At the 2018 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging (SNMMI), June 23-26...
SNMMI Image of the Year Highlights Theranostic Approach for Advanced Prostate Cancer

IMAGE OF THE YEAR: PSMA PET before and after lutetium-177 PSMA617 theranostics in 8 patients with metastatic prostate cancer who exhausted standard therapeutic options.

68Ga-PSMA11 PET maximum intensity projection (MIP) images at baseline and 3 months after 177Lu-PSMA617 in 8 patients with PSA decline ≥ 98 percent in a prospective phase II study. Any disease with SUV over 3 is in red. Credit: Michael Hofman, John Violet, Shahneen Sandhu, Justin Ferdinandus, Amir Iravani, Grace Kong, Aravind Ravi Kumar, Tim Akhurst, Sue Ping Thang, Price Jackson, Mark Scalzo, Scott Williams and Rodney Hicks, Peter MacCallum Cancer Centre, Melbourne, Australia.

News | PET Imaging | June 29, 2018
June 29, 2018 — In the battle against metastatic castrate-resistant prostate cancer, studies have demonstrated a high...
MILabs Introduces Futuristic PET Capabilities on New VECTor6 System
Technology | PET Imaging | June 28, 2018
June 28, 2018 — At the 2018 Society of Nuclear Medicine and Molecular Imaging (SNMMI) annual meeting, June 23-26, in...
Philips North America and GE Healthcare Win IMV PET Imaging ServiceTrak Awards
News | PET Imaging | June 25, 2018
June 25, 2018 — IMV, part of the Science and Medicine Group and a market research and business intelligence provider to...