April 28, 2008 - Many women with a faulty breast cancer gene may be at greater risk of the disease due to extra risk-amplifying genes, according to research published this month in the American Journal of Human Genetics, directly influencing how women with a family history of the disease are monitored.
Researchers at the University of Pennsylvania School of Medicine join an international consortium of research groups that looked at more than 10,000 women carrying a BRCA1 or BRCA2 mutation for breast-cancer risk.