News | September 23, 2009

Philips, Bruker Sign MOU to Develop Magnetic Particle Imaging Scanners

New medical imaging technology, Magnetic Particle Imaging (MPI), which generates unprecedented real-time images of blood flow and heart movement may improve disease diagnosis and treatment planning.

September 23, 2009 - At the 2009 World Molecular Imaging Congress (WMIC) in Montreal, Royal Philips Electronics and Bruker BioSpin, a division of Bruker Corp., today announced that they have signed a memorandum of understanding (MOU) for the development of magnetic particle imaging (MPI) scanners, a new imaging technology, for the preclinical market.

The partnership would unite Philips’ strength in medical imaging and Bruker BioSpin’s leadership in analytical magnetic resonance instruments and preclinical Magnetic Resonance Imaging (MRI).

Under the terms of the MOU, Bruker BioSpin intends to develop and manufacture the preclinical MPI scanner at its facilities in Ettlingen, Germany. Both parties intend to co-market the resulting solution. Preclinical imaging has emerged as a powerful tool in disease studies, translational research and drug discovery. Philips and Bruker BioSpin believe that the addition of MPI as a complementary preclinical imaging technique has great potential to help researchers gain new insights in disease processes at the organ, cellular and molecular level.
MPI is a new medical imaging technology developed by scientists at Philips. It uses the magnetic properties of iron-oxide nanoparticles to produce three-dimensional images of the concentration of nanoparticles injected into the bloodstream. The potential of the technology for medical and industrial research and, ultimately, patient care, was demonstrated in a publication which appeared in the March issue of Physics in Medicine and Biology in 2009 (Volume 54, issue 5). It was shown that MPI technology can be used to produce real-time images that accurately capture the activity in the cardiovascular system of a mouse.
“We are very pleased about this collaboration with Philips on this exciting technology. Magnetic Particle Imaging is expected to allow scientists to explore an extensive range of new imaging capabilities and applications in preclinical research, ” said Wulf-Ingo Jung, managing mirector of Bruker BioSpin MRI GmbH. “The highly sensitive visualization of functional characteristics in vivo at high temporal resolution bears great potential for small animal imaging, especially when combined with high spatial resolution morphological MRI.”
“Through its combined speed, resolution and sensitivity, our Magnetic Particle Imaging technology has great potential for the diagnosis, therapy planning and therapy response assessment for major diseases such as heart disease and cancer,” said Diego Olego, senior vice president and CTO of Philips Healthcare. “We are excited about the agreement with Bruker BioSpin as it will lead to the availability of MPI scanners for preclinical research studies, which is a prerequisite for establishing the value of this promising new technology for patient care.”
A key success factor for the effective translation of new imaging concepts into practice are partnerships with leading academic medical institutions, industrial partners and governments. Bringing together such partnerships is one of the underlying principles behind Philips’ policy of open innovation. The results obtained in the MAGIC (Magnetic Particle Imaging for Cardio-Vascular Applications) research project conducted at the Philips Research Laboratories in Hamburg (Germany), have significantly contributed to the development of MPI. The project was funded by the German Federal Ministry of Education and Research under grant Number 13N9079 as part of the NanoForLife Framework Program. The project was started in 2006 and will finish by the end of this year.

Related Content

Philips Introduces Technology Maximizer Program for Imaging Equipment Upgrades
Technology | Imaging | January 17, 2018
January 17, 2018 — Philips recently announced the launch of Technology Maximizer, a cross-modality program designed t
Russian Team Developing New Technology to Significantly Reduce MRI Research Costs
News | Magnetic Resonance Imaging (MRI) | January 16, 2018
January 16, 2018 — Researchers from the NUST MISIS Engineering Center for Industrial Technologies in Russia have deve
Smartphone Addiction Creates Imbalance in Brain
News | Mobile Devices | January 11, 2018
Researchers have found an imbalance in the brain chemistry of young people addicted to smartphones and the internet,...
Emergency Radiologists See Inner Toll of Opioid Use Disorders

Rates of Imaging Positivity for IV-SUDs Complications. Image courtesy of Efren J. Flores, M.D.

News | Clinical Study | January 11, 2018
January 11, 2018 – Emergency radiologists are seeing a high prevalence of patients with complications related to opio
Study Finds No Evidence that Gadolinium Causes Neurologic Harm

MR images through, A, C, E, basal ganglia and, B, D, F, posterior fossa at level of dentate nucleus. Images are shown for, A, B, control group patient 4, and the, C, D, first and, E, F, last examinations performed in contrast group patient 13. Regions of interest used in quantification of signal intensity are shown as dashed lines for globus pallidus (green), thalamus (blue), dentate nucleus (yellow), and pons (red).

News | Contrast Media | January 11, 2018
January 11, 2018 — There is no evidence that accumulation in the brain of the element gadolinium speeds cognitive dec
Weight Loss Through Exercise Alone Does Not Protect Knees
News | Orthopedic Imaging | January 11, 2018
January 11, 2018 – Obese people who lose a substantial amount of weight can significantly slow down the degeneration
Neurofeedback Shows Promise in Treating Tinnitus

The standard approach to fMRI neurofeedback. Image courtesy of Matthew Sherwood, Ph.D.

News | Magnetic Resonance Imaging (MRI) | January 11, 2018
January 11, 2018 — Researchers using...
Male Triathletes May Be Putting Their Heart Health at Risk
News | Cardiac Imaging | January 09, 2018
Competitive male triathletes face a higher risk of a potentially harmful heart condition called myocardial fibrosis,...
State-of-the-Art MRI Technology Bypasses Need for Biopsy
News | Magnetic Resonance Imaging (MRI) | January 09, 2018
January 9, 2018 – The most common type of tumor found in the kidney is generally quite small (less than 1.5 in).
New Studies Show Brain Impact of Youth Football
News | Neuro Imaging | January 09, 2018
School-age football players with a history of concussion and high impact exposure undergo brain changes after one...
Overlay Init