News | Coronavirus (COVID-19) | May 19, 2021

Recognition of abnormal axillary lymph node or deltoid uptake on PET examinations performed after COVID-19 vaccination aid interpreting physicians and reduce unnecessary biopsies

According to an open-access article in ARRS’ American Journal of Roentgenology (AJR), increased axillary lymph node or ipsilateral deltoid uptake is occasionally observed on FDG or 11C-choline PET performed after Pfizer-BioNTech or Moderna COVID-19 vaccination

(A) 57-year-old woman with right upper arm melanoma who received the first dose of the COVID-19 vaccine (Pfizer-BioNTech) in the left deltoid 15 days prior to FDG PET/CT. FDG uptake is observed within left axillary lymph nodes (arrow, SUVmax = 9.3).

(B) 62-year-old man with metastatic prostate carcinoma who received the second dose of COVID-19 vaccine (Pfizer-BioNTech) in the right deltoid 7 days prior to 11C-choline PET/CT. 11C-choline uptake is observed within right axillary lymph nodes (arrows, SUVmax = 3.1) as well as the right deltoid muscle (circle, SUVmax = 1.7).


May 19, 2021 — According to an open-access article in ARRS’ American Journal of Roentgenology (AJR), increased axillary lymph node or ipsilateral deltoid uptake is occasionally observed on FDG or 11C-choline PET performed after Pfizer-BioNTech or Moderna COVID-19 vaccination.

“Recognition of occasional abnormal axillary lymph node or deltoid uptake on PET examinations performed after COVID-19 vaccination will aid interpreting physicians and reduce unnecessary biopsies,” wrote corresponding author Jason R. Young from the department of radiology at Mayo Clinic in Rochester, Minn.

Young and colleagues’ retrospective study included 67 patients (43 men, 24 women; mean age, 75.6 years) who underwent PET examination (PET/CT in 66, PET/MRI in 1; FDG in 54, 11C-choline in 13) between December 14, 2020 and March 10, 2021 following COVID-19 vaccination (Pfizer-BioNTech vaccine in 52, Moderna vaccine in 15) and who had undergone pre-vaccination PET without visible axillary node uptake. PET was performed a median of 13 and 10 days after vaccination in patients who had received one (n = 44) and two (n = 23) doses, respectively.

“We observed positive axillary lymph nodes in 7.4% of FDG and 23.1% of 11C-choline PET examinations performed after COVID-19 vaccination (10.4% of PET examinations) in patients without visible axillary nodal uptake on PET performed before vaccination,” Young et al. concluded. Ipsilateral deltoid uptake with a characteristic appearance was observed in 14.5% of examinations, and one patient exhibited extraaxillary lymph node uptake (ipsilateral supraclavicular uptake on FDG PET).

“All examinations showing positive axillary lymph nodes were performed within 24 days of vaccination,” the authors of this AJR article added.

For more information: www.arrs.org

 

Related COVID Vaccine Axillary Adenapathy Content:

COVID-19 Vaccine Can Cause False Positive Cancer Diagnosis

Help Spread Awareness of Potential COVID-19 Vaccine Imaging Side-effects

VIDEO: COVID Vaccine May Cause Enlarged Lymph Nodes on Mammograms — Interview with Constance "Connie" Lehman, M.D.

COVID-19 Vaccination Axillary Adenopathy Detected During Breast Imaging

CMS Now Requires COVID-19 Vaccinations for Healthcare Workers by January 4

PHOTO GALLERY: How COVID-19 Appears on Medical Imaging

Find more radiology related COVID content 

Related Content

Feature | Radiology Business | By Melinda Taschetta-Millane

Did you know that Imaging Technology News (ITN) maintains more than 40 comparison charts of product specifications from ...

Time August 12, 2022
arrow
News | Radiology Education

August 11, 2022 — After a three-year break, this spring featured the return of the anticipated Canon Roadshow Events ...

Time August 11, 2022
arrow
News | Computed Tomography (CT)

August 11, 2022 — For the first time, researchers successfully captured CT images of an entire woolly mammoth tusk ...

Time August 11, 2022
arrow
News | Radiology Imaging

August 11, 2022 — Bracco Imaging S.p.A. has announced the renewal of the “Bracco Fellowships” initiative, in partnership ...

Time August 11, 2022
arrow
News | Ultrasound Imaging

August 10, 2022 — Butterfly Network, Inc., a digital health company transforming care with handheld, whole-body ...

Time August 10, 2022
arrow
News | Point-of-Care Ultrasound (POCUS)

August 10, 2022 — Mindray North America, a global leader and developer of healthcare technologies and solutions for ...

Time August 10, 2022
arrow
News | X-Ray

August 5, 2022 — GE Healthcare released its most advanced fixed X-ray system yet, the next-generation Definium 656 HD ...

Time August 05, 2022
arrow
News | Lung Imaging

August 3, 2022 — Structural differences in lung airways between men and women may be the cause of differences in chronic ...

Time August 03, 2022
arrow
Feature | Lung Imaging

August 1, 2022 — In recognition of World Lung Cancer Day, the American Lung Association announced new patient resources ...

Time August 01, 2022
arrow
Feature | Radiology Business | By Melinda Taschetta-Millane

Here is what you and your colleagues found to be most interesting in the field of medical imaging during the month of ...

Time August 01, 2022
arrow
Subscribe Now