Feature | Magnetic Resonance Imaging (MRI) | December 22, 2016

Runners' Brains May Be More Connected, Research Shows

MRI scans show that running may affect the structure and function of the brain in ways similar to complex tasks like playing a musical instrument

MRI brain

If you're thinking about taking up running as your New Year's resolution and still need some convincing, consider this: MRI scans reveal that endurance runners' brains have greater functional connectivity than the brains of more sedentary individuals.

University of Arizona researchers compared brain scans of young adult cross country runners to young adults who don't engage in regular physical activity. The runners, overall, showed greater functional connectivity — or connections between distinct brain regions — within several areas of the brain, including the frontal cortex, which is important for cognitive functions such as planning, decision-making and the ability to switch attention between tasks.

Although additional research is needed to determine whether these physical differences in brain connectivity result in differences in cognitive functioning, the current findings, published in the journal Frontiers in Human Neuroscience, help lay the groundwork for researchers to better understand how exercise affects the brain, particularly in young adults.

UA running expert David Raichlen, an associate professor of anthropology, co-designed the study with UA psychology professor Gene Alexander, who studies brain aging and Alzheimer's disease as a member of the UA's Evelyn F. McKnight Brain Institute.

"One of the things that drove this collaboration was that there has been a recent proliferation of studies, over the last 15 years, that have shown that physical activity and exercise can have a beneficial impact on the brain, but most of that work has been in older adults," Raichlen said.

"This question of what's occurring in the brain at younger ages hasn't really been explored in much depth, and it's important," he said. "Not only are we interested in what's going on in the brains of young adults, but we know that there are things that you do across your lifespan that can impact what happens as you age, so it's important to understand what's happening in the brain at these younger ages."

Along with their colleagues, Raichlen and Alexander compared the MRI scans of a group of male cross country runners to the scans of young adult males who hadn't engaged in any kind of organized athletic activity for at least a year. Participants were roughly the same age — 18 to 25 — with comparable body mass index and educational levels.

The scans measured resting state functional connectivity, or what goes on in the brain while participants are awake but at rest, not engaging in any specific task.

The findings shed new light on the impact that running, as a particular form of exercise, may have on the brain.

Previous studies have shown that activities that require fine motor control, such as playing a musical instrument, or that require high levels of hand-eye coordination, such as playing golf, can alter brain structure and function. However, fewer studies have looked at the effects of more repetitive athletic activities that don't require as much precise motor control — such as running. Raichlen's and Alexander's findings suggest that these types of activities could have a similar effect.

"These activities that people consider repetitive actually involve many complex cognitive functions — like planning and decision-making — that may have effects on the brain," Raichlen said.

Since functional connectivity often appears to be altered in aging adults, and particularly in those with Alzheimer's or other neurodegenerative diseases, it's an important measure to consider, Alexander said. And what researchers learn from the brains of young adults could have implications for the possible prevention of age-related cognitive decline later on.

"One of the key questions that these results raise is whether what we're seeing in young adults — in terms of the connectivity differences — imparts some benefit later in life," said Alexander, who also is a professor of neuroscience and physiological sciences. "The areas of the brain where we saw more connectivity in runners are also the areas that are impacted as we age, so it really raises the question of whether being active as a young adult could be potentially beneficial and perhaps afford some resilience against the effects of aging and disease."

For more information: uanews.arizona.edu/story/runners-brains-may-have-more-connectivity-ua-research-shows

Related Content

Prenatal MRI of a Zika fetus showing enlarged cerebral fluid space, dilation of the cerebral ventricles, thinning of brain tissue, poorly developed cerebellum and the absence of brain cortical gyri. (Image coutesy of RSNA)

Feature | Women's Health | January 23, 2017 | Dave Fornell
The rapid spread of Zika virus in the Western Hemisphere this past year has caused great alarm in the United States,
breast cancer screening, substantial overdiagnosis, Annals of Internal Medicine study
News | Mammography | January 19, 2017
Breast cancer screening in Denmark was associated with a substantial increase in the incidence of nonadvanced tumors...
automated volumetric breast density, Elizabeth Wende Breast Care, EWBC, American Journal of Roentgenology, mammographic sensitivity
News | Breast Density | January 18, 2017
Researchers from Elizabeth Wende Breast Care (EWBC) have demonstrated that automated volumetric breast density has a...
stress, brain activity, cardiovascular risk, PET-CT, MGH, ISSMS, The Lancet study
News | Neuro Imaging | January 18, 2017
A study led by Massachusetts General Hospital (MGH) and Icahn School of Medicine at Mount Sinai (ISSMS) investigators...
Iradimed, FDA clearance, MRIdium 3860+ IV infusion pump system, MRI-compatible,
Technology | Magnetic Resonance Imaging (MRI) | January 17, 2017
Iradimed Corp. announced in December that it received U.S. Food and Drug Administration (FDA) 510(k) clearance for its...
Siemens, Biogen, joint development, MRI tools, multiple sclerosis
News | Neuro Imaging | January 17, 2017
January 17, 2017 — Siemens Healthineers and Biogen have announced the companies plan to jointly develop...
MRgFUS
News | Focused Ultrasound Therapy | January 17, 2017
Insightec, a leader in MR-guided focused ultrasound (MRgFUS) therapy, announced today that the Japanese Ministry of...
MIM Software, BK Ultrasound, bkFusion, MRI Fusion Biopsy System, prostate cancer, RSNA 2016
Technology | Fusion Imaging Software | January 03, 2017
MIM Software Inc. announced in November the commercial introduction of its MRI (magnetic resonance imaging) Prostate...
Philips, e-Alert, MRI, Most Innovative IoT Solution Award, World Communication Awards
News | Magnetic Resonance Imaging (MRI) | January 03, 2017
Royal Philips recently announced that its e-Alert was awarded “Most Innovative IoT Solution” at the World Communication...
magnetoencephalography, MEG, brain scans, concussion detection, Simon Fraser University, SFU study, PLOS Computational Biology
News | Neuro Imaging | January 03, 2017
Simon Fraser University researchers have found that high-resolution brain scans, coupled with computational analysis,...
Overlay Init