News | June 26, 2007

Philips Tests MRI/PET Diagnostic Solution for Neurodegenerative Diseases

June 27, 2007 - The University Medical Center Hamburg-Eppendorf (UKE) and Royal Philips Electronics have developed a computer aided diagnosis system for neurodegenerative diseases to support clinicians in diagnosing the onset and type of disease as early as possible, and the tool is set to undergo clinical evaluation at UKE to fine-tune the its ability to detect and differentiate the three most common types of neurodegenerative disease – Alzheimer’s Disease, Lewy-body Dementia and Frontotemporal Dementia.

The software tool developed by Philips Research and UKE overlays anatomical images of the brain obtained from MRI scans with PET scans that display brain activity – specifically the uptake of glucose that fuels brain activity. By using advanced image processing and computer learning techniques in combination with a database of reference brain-scans, the system then analyses the images automatically and displays anomalous brain patterns. Based on these patterns, it then suggests a diagnosis. As a result, the system will help less experienced doctors to achieve the same diagnostic accuracy as highly trained specialists.

The clinical evaluation that is about to start will run the computer aided diagnostic system alongside UKE’s existing dementia diagnosis procedures with the aim of fine-tuning the system’s ability to detect and differentiate the three most common types of neurodegenerative disease – Alzheimer’s Disease, Lewy-body Dementia and Frontotemporal Dementia.

The hope is that such a system will ultimately mean a better quality of life for patients by enabling earlier prescription of drugs that delay progression of the disease, and hence delay the worst effects of dementia. It will also provide pharmaceutical companies and clinicians with a valuable tool for the development and testing of new, potentially curative drugs for neurodegenerative diseases such as Alzheimer’s.

“In the not too distant future there is going to be much greater demand for the accurate early diagnosis of neurodegenerative disease and not everyone will have access to the clinical expertise of a university hospital to obtain it,” said Dr. Ralph Buchert of the Department of Nuclear Medicine at UKE. “The availability of an automated system will help less experienced physicians to achieve the same high level of accuracy in their diagnoses.”

For more information: www.medical.philips.com

Related Content

Washington University in St. Louis Begins Clinical Treatments With ViewRay MRIdian Linac
News | Image Guided Radiation Therapy (IGRT) | June 14, 2018
June 14, 2018 — The Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine in S
PET/CT Changes Care for 59 Percent of Suspected Recurrent Prostate Cancer Cases
News | Prostate Cancer | June 13, 2018
A recently presented investigational clinical trial evaluated the impact of 18F fluciclovine positron emission...
Reduced hippocampal volume on MRI

This figure shows reduced hippocampal volume over the course of 6 years as seen on progressive volumetric analysis and also coronal MRI evaluations (arrows).Progressive volume loss in the mesial temporal lobe on MRI is a characteristic imaging feature of AD. This patient was a case of Alzheimer’s Dementia.

 

News | Neuro Imaging | June 12, 2018
According to a UCLA Medical Center study, a new technology shows the potential to help doctors better determine when...
High Prevalence of Atherosclerosis Found in Lower Risk Patients
News | Magnetic Resonance Imaging (MRI) | June 08, 2018
Whole-body magnetic resonance angiography (MRA) found a surprisingly high prevalence of atherosclerosis in people...
Philips Receives FDA 510(k) for Ingenia Elition MR System
Technology | Magnetic Resonance Imaging (MRI) | June 07, 2018
Philips announced that it has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) for its...
News | Computed Tomography (CT) | May 21, 2018
The Istituto Oncologico Veneto (IOV) in Padua, Italy, has acquired MILabs’ latest-generation Versatile Emission...
New Studies Highlight MRI Use for Prostate Cancer Screening and Management
News | Magnetic Resonance Imaging (MRI) | May 21, 2018
Three new studies presented at the 113th annual meeting of the American Urological Association (AUA) highlight the...
MRI "Glove" Provides New Look at Hand Anatomy

An experiment showed that a glove-shaped detector could yield images of bones, cartilage, and muscles interacting as a hand 'plays piano.' Traditionally, MRI had required patients to remain strictly motionless.Image courtesy of Nature Biomedical Engineering; Bei Zhang, Martijn Cloos, Daniel Sodickson

News | Magnetic Resonance Imaging (MRI) | May 17, 2018
A new kind of magnetic resonance imaging (MRI) component in the shape of a glove delivers the first clear images of...
PET Imaging Agent Could Provide Early Diagnosis of Rheumatoid Arthritis

Coronal 18F-FEDAC PET/CT section of a mouse with collagen-induced arthritis. (A) On day 23 and day 37, increased uptake is noted in the front and hind paws of this mouse with collagen-induced arthritis. (B) Predictive performance of day 23 18F-FEDAC uptake for the development of clinical arthritis. ROC = receiver operating characteristic; Sn = sensitivity; Sp = specificity. Credit: Seoul National University and Ewha Womans University, Seoul, South Korea

News | PET Imaging | May 17, 2018
A novel positron emission tomography (PET) tracer developed by Korean researchers can visualize joint inflammation and...
FDA Clears Medic Vision's iQMR MRI Image Enhancement Technology

Image courtesy of Medic Vision Imaging Solutions

Technology | Magnetic Resonance Imaging (MRI) | May 15, 2018
May 15, 2018 — Medic Vision Imaging Solutions Ltd. announced that the U.S.
Overlay Init