August 4, 2011 – Published last week in The American Journal of Roentgenology, researchers from Swedish Cancer Institute and the University of Washington used positron emission mammography (PEM) to find a correlation between fludeoxyglucose (FDG) uptake values and the prognostic factors that predict breast cancer survival. The highest FDG levels were in the most aggressive cancer type – triple negative cancers. Women with triple negative breast cancer have a higher mortality because there is no tailored therapy available to them. PEM may now benefit this patient population as it may help identify when a chemotherapeutic regimen is not working. PEM also has the potential to play a role in initial staging of breast cancer in patients at high risk for multifocal or multicentric disease who desire breast conservation therapy as an alternative to breast MRI.
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