News | Coronavirus (COVID-19) | October 22, 2020

Spectral CT with electron density imaging improves assessment of lung lesion extent in patients with RT-PCR-confirmed COVID-19

A, Initial conventional axial CT image shows no noticeable lung damage (within red box) in right upper lobe. B, Electron density spectral CT image obtained at same time as image in A shows lesions (within red box) in right upper lobe. C, Follow-up conventional axial chest CT image obtained 5 days after images in A and B confirm presence of lesions (within red box) in right upper lobe.

A, Initial conventional axial CT image shows no noticeable lung damage (within red box) in right upper lobe. B, Electron density spectral CT image obtained at same time as image in A shows lesions (within red box) in right upper lobe. C, Follow-up conventional axial chest CT image obtained 5 days after images in A and B confirm presence of lesions (within red box) in right upper lobe. Image courtesy of the American Roentgen Ray Society (ARRS), American Journal of Roentgenology (AJR)


October 22, 2020 — According to an open-access article in ARRS' American Journal of Roentgenology (AJR), the use of spectral computed tomography (CT) with electron density imaging could improve the assessment of lung lesion extent in patients with early-stage coronavirus disease (COVID-19).

"In the present study," wrote Beatrice Daoud and colleagues at Antony's Private Hospital in France, "we report the first retrospective data from the spectral chest CT findings of patients with reverse transcription-polymerase chain reaction (RT-PCR)-confirmed COVID-19 (i.e., patients with positive RT-PCR test results)."

Since March 17, 2020, every patient who has had CT performed at the authors' institution for either suspected or RT-PCR-confirmed COVID-19 has undergone dual-layer detector-based spectral CT (IQon Spectral CT, Philips Healthcare). To evaluate the potential benefit of spectral imaging--electron density imaging, especially--two experienced thoracic radiologists reviewed the cases of four patients who each underwent two chest CT scans for confirmed COVID-19. Reconstructing the spectral CT images using the same standard soft kernel (filter B) and a similar iterative method that was used to acquire the conventional CT images, Daoud's team also compared initial conventional CT images with follow-up conventional CT images.

In all four patients, their pulmonary lesions (45 ground-glass opacities, overall) were more conspicuous on electron density images than on initial conventional CT images and were clearly confirmed on follow-up conventional CT images. Moreover, lesion extent, assessed via semiquantitative reporting scale denoting surface area involvement for each lobe, was easier to ascertain on electron density images. With Daoud and colleagues' results indicating electron density imaging improves early assessment of the extent of ground-glass opacities that could be missed by conventional CT, electron density showed the most promising results by enhancing the contrast of ground-glass opacities compared with the normal lung.

"We reviewed conventional chest CT images obtained with a parenchyma kernel and standard lung window setting, as is usually the case in everyday radiology practice," Daoud et al. explained, adding that they compared these images with conventional images obtained using a soft mediastinum kernel and standard lung window setting, conventional images obtained using a soft mediastinum kernel and narrow lung window setting, virtual low-monoenergy images, virtual high-monoenergy images, and electron density images.

"Our results suggest that the better ground-glass opacity visualization obtained using electron density imaging may be chiefly related to the increased visual noise in the image with soft kernel reconstruction and narrow lung window setting compared with electron density imaging, for which narrowing the window does not impair image quality," the authors of this AJR article concluded.

For more information: www.arrs.org

Related Coronavirus Content:

How COVID-19 Appears on Medical Imaging — Photo Gallery

VIDEO: Imaging COVID-19 With Point-of-Care Ultrasound (POCUS)

Cardiac Imaging Best Practices During the COVID-19 Pandemic

RSNA Publishes COVID-19 Best Practices for Radiology Departments

ASE Guidelines for the Protection of Echocardiography Providers During the COVID-19 Outbreak
New CT Scoring Criteria for Timely Diagnosis, Treatment of Coronavirus Disease

FDA Issues New Policy for Imaging Systems During COVID-19

VIDEO: COVID-19 Precautions for Cardiac Imaging —  Interview with Stephen Bloom, M.D.

A Review of Studies Cautions Against Chest CT for Coronavirus Diagnosis

New Research Finds Chest X-ray Not Reliable Diagnostic Tool for COVID-19

VIDEO: Radiology Industry Responding to COVID-19

University of Washington Issues Radiology Policies for COVID-19

VIDEO: Best Practices for Nuclear Cardiology During the COVID-19 Pandemic — Interview with Hicham Skali, M.D.

New Research Highlights Blood Clot Dangers of COVID-19

Survey Reveals Most Medical Practices are Now Using Telehealth Due to COVID-19

CMS Offers Recommendations on Reopening Healthcare in Areas of Low COVID-19 Cases

CT Provides Best Diagnosis for Novel Coronavirus (COVID-19)

Radiology Lessons for Coronavirus From the SARS and MERS Epidemics

Radiologists Describe Coronavirus CT Imaging Features

CT Imaging of the 2019 Novel Coronavirus (2019-nCoV) Pneumonia

ACC COVID-19 recommendations for the cardiovascular care team

VIDEO: What Cardiologists Need to Know about COVID-19 — Interview with Thomas Maddox, M.D.

The Cardiac Implications of Novel Coronavirus


Related Content

News | Radiology Business

February 2, 2023 — Five additional imaging centers across Allegheny Health Network (AHN) have been recognized by the ...

Time February 02, 2023
arrow
Feature | Radiology Business | By Melinda Taschetta-Millane

Here is a recap of what ITN viewers found most interesting during the month of January: 1. A Look at the Changes in 2023 ...

Time February 01, 2023
arrow
News | Ultrasound Imaging

January 31, 2023 — Esaote, a leading Italian company in the biomedical sector – in ultrasound, dedicated MRI and medical ...

Time January 31, 2023
arrow
News | Digital Pathology

January 27, 2023 — Fujifilm has completed its asset purchase of Inspirata, Inc.’s digital pathology business effective ...

Time January 27, 2023
arrow
News | Magnetic Resonance Imaging (MRI)

January 25, 2023 — On November 11th, 2022 at the Southern Hills Hospital in Las Vegas, USA, Robotic Spine Surgeon Dr ...

Time January 25, 2023
arrow
Feature | Enterprise Imaging

The Imaging Technology News (ITN) team was saddened to hear of the untimely passing of Frank Pecaitis, US North American ...

Time January 24, 2023
arrow
Feature | Radiology Imaging | By Melinda Taschetta-Millane

Have you read the January/February 2023 issue of Imaging Technology News? If not, take some time out of your busy ...

Time January 24, 2023
arrow
News | Digital Radiography (DR)

January 24, 2023 — Carestream Health was awarded 20 new patents in 2022 for global advances in artificial intelligence ...

Time January 24, 2023
arrow
News | Radiology Imaging

January 23, 2023 — Canon Medical Systems has released a new eBook featuring its new medical imaging roadshow. This new ...

Time January 23, 2023
arrow
News | Ultrasound Imaging

January 23, 2023 — Clarius Mobile Health, a leading provider of high-definition handheld ultrasound systems, introduces ...

Time January 23, 2023
arrow
Subscribe Now