News | Molecular Imaging | October 26, 2017

New funding from Dutch Cancer Society will allow further testing of technique to track prostate specific membrane antigen (PSMA) in real time

Netherlands Cancer Institute Exploring Molecular Imaging Technology for Prostate Cancer Surgery

October 26, 2017 — The Netherlands Cancer Institute (NKI) announced it has received funding from the Dutch Cancer Society (KWF Kankerbestrijding) to test whether a novel molecular imaging technology can guide prostate cancer surgery. The project will evaluate the imaging technology’s ability to detect prostate cancer during surgery, with the aim of performing more accurate removal of cancerous tissue.

Prostate cancer is the most common cancer among men in Europe with over 350,000 diagnosed in Europe every year. Complete removal of malignant tissue during prostate cancer surgery can be challenging, especially in later-stage disease, as it can be difficult to distinguish between cancerous and non-cancerous tissue. Accordingly, there is a crucial need for new technologies to help surgeons visualize cancer in real time during an operation to ensure that the cancer has been completely removed.

In the joint research project, the Netherlands Cancer Institute, University of Twente and industry partners Lightpoint Medical and Philips will evaluate a novel molecular imaging technology to image the prostate cancer biomarker prostate specific membrane antigen (PSMA) during surgery. If successful, the technology will be tested in larger clinical trials, with the aim of sparing healthy tissue and reducing recurrence rates in prostate cancer surgery.

Marcel Stokkel, M.D., nuclear medicine physician at NKI, commented, “If this technique is successful, we will be able to guide the urologist in the most optimal way by combining pre-operative staging with per-operative imaging using the same tracer. If the resection margins can be assessed with highest accuracy during surgery, we might become able to improve recurrence and survival rates. The collaboration with Lightpoint Medical, Philips and the University of Twente is the most optimal setting to reach this goal and to complete this study.”

For more information: www.nki.nl

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