News | Magnetic Resonance Imaging (MRI) | February 01, 2023

AJR Systematic Review and Meta-Analysis 

PRISMA flow diagram shows identification, screening, and inclusion of studies

PRISMA flow diagram shows identification, screening, and inclusion of studies 

February 1, 2023 — According to an accepted manuscript published in ARRS’ American Journal of Roentgenology (AJR)MRI-based surveillance after surgical treatment of musculoskeletal soft-tissue sarcomas (STS) shows utility for detecting clinically occult local recurrences (LRs), potentially improving patient outcomes. 

“When used at a high intensity, MRI-based surveillance can detect many clinically occult LRs, although the studies are small, occasionally conflicting, and often of poor quality,” wrote corresponding author Natalia Gorelik, MD, from the department of diagnostic radiology at McGill University Health Center in Montreal, Quebec, Canada. “A survival benefit could be associated with imaging use, but further research is needed to evaluate the causality of any observed survival differences.”  

In this AJR systematic review and meta-analysis, Gorelik et al. systematically searched multiple electronic databases through November 2022 for controlled trials and cohort studies on the usefulness of MRI-based surveillance for musculoskeletal STS. A total of 4,821 unique titles and abstracts were identified. After screening for eligibility and snowball sampling, 19 studies were included; all were retrospective cohorts. 

Using an adapted Newcastle-Ottawa scale for assessing bias risk, random effects meta-analyses of the proportion of LRs discovered by MRI, as opposed to clinically, were conducted. The association of low- versus high-intensity surveillance—high intensity defined as at least one local surveillance imaging examination for low-risk tumors, as well as at least three for high-risk tumors during the first 2 posttreatment years—with the proportion of LR detected on MRI was assessed with a chi-square test of subgroup differences. 

Ultimately, when MRI-based surveillance of musculoskeletal STSs was used at a high intensity, 53% (95% CI, 36–71%) of LRs were discovered with MRI. Four studies reported trends toward better survival for imaging-detected LRs or with more frequent imaging use.  

“Although definite conclusions on the value of MRI-based surveillance are challenging to draw,” the authors of this AJR accepted manuscript acknowledged, “this study provides a comprehensive overview of the available evidence on the topic.” 

For more information: 

Related Content

News | Magnetic Resonance Imaging (MRI)

April 5, 2024 — Osteoarthritis — not age — may play the greatest role in determining the utility of MRI for patients 45 ...

Time April 05, 2024
News | Radiology Business

April 4, 2024 — FUJIFILM Healthcare Americas Corporation, a leading provider of diagnostic and enterprise imaging ...

Time April 04, 2024
News | Population Health

April 4, 2024 — A new study found increased coronary vessel wall thickness that was significantly associated with ...

Time April 04, 2024
News | Radiation Oncology

April 2, 2024 — In a 10-center study, microwave ablation offered progression free survival rates and fewer complications ...

Time April 02, 2024
News | Molecular Imaging

March 29, 2024 — Magnetic resonance imaging (MRI) is a cornerstone in the landscape of medical diagnostics, celebrated ...

Time March 29, 2024
News | Electronic Medical Records (EMR)

March 28, 2024 — Immediately releasing radiology reports under the 21st Century Cures Act (Cures Act) empowers patients ...

Time March 28, 2024
News | FDA

March 27, 2024 — SyntheticMR announced that its next-generation imaging solution, SyMRI 3D, has received FDA 510(k) ...

Time March 27, 2024
News | ACR

March 21, 2024 — The Advanced Research Projects Agency for Health (ARPA-H) has appointed American College of Radiology ...

Time March 21, 2024
News | Breast Imaging

March 20, 2024 — IceCure Medical Ltd., developer of the ProSense System, a minimally-invasive cryoablation technology ...

Time March 20, 2024
News | RSNA

March 19, 2024 — Radiology Advances, the first exclusively open-access journal of the Radiological Society of North ...

Time March 19, 2024
Subscribe Now