News | Nuclear Imaging | February 02, 2022

Mo-99 supply issues continue following HFR shutdown

The Petten High Flux Reactor in Petten, Netherlands. Image by Tetzemann - Own work, CC BY 3.0, https://commons.wikimedia.org/w/index.php?curid=83953498

The Petten High Flux Reactor in Petten, Netherlands. Image by Tetzemann - Own work, CC BY 3.0, https://commons.wikimedia.org/w/index.php?curid=83953498


February 2, 2022 — Nuclear Medicine Europe has announced that the HFR reactor in Petten, Netherlands, did not resume operations as planned on January 20 due to the detection of a water leak in a cooling system. The planned first 2022 HFR cycle scheduled from January 20 until February 20, 2022 was subsequently canceled. The Nuclear Medicine Europe Emergency Response Team held another call on January 31 with representatives of HFR reactor operator NRG and was informed that the progress on HFR inspections and options for restoring functionality is going well. The endoscopic inspections of the difficult to access piping have been performed and the observations provide strong indication of the origin of the leak and provides important information for assessing the root cause. The HFR project team has identified different options for restoring functionality and intends to select the preferred option in the course of this week. NRG has discussed the generic plan of an approach with the Dutch nuclear safety authority ANVS. At this time, a target date for HFR restart cannot be yet be provided as it is dependent upon selection of the preferred technical option and further elaboration of planning. NRG will provide the next update on Monday 7 February 2022. The ERT was also given updates from research reactors and Mo-99 producers in regard to actions underway to limit impacts on Mo-99/Tc-99m supply. However, some shortages of Mo-99/Tc-99m will be inevitable untinul approximately a week after the BR2 resumes operations on February 12th. Reports also indicated some impact on both Lu-177 and I-131 availability. Medical institutions should contact their radioisotope suppliers to determine the specific impact on their orders. NMEu will communicate again with stakeholders on Feb. 7, 2022. 

Related Content:

SNMMI Issues Alert That HFR Outage Will Impact Isotope Supply

NorthStar Medical Radioisotopes Advances Focus on Therapeutic and Specialized SPECT Radiopharmaceuticals

How Nuclear Fusion is Revolutionizing Medical Isotope Production

FDA Approves Additional Molybdenum-99 (Mo-99) Filling Lines at NorthStar Medical Radioisotopes

Medical Isotope Industry Opposes Export of Highly Enriched Uranium for IRE

IBA and NorthStar Medical Radioisotopes Expand Collaboration to Enable Global Availability of Tc-99m


Related Content

News | Radiation Therapy

Feb. 4, 2026 — On World Cancer Day (02.04.26), the American Society for Radiation Oncology (ASTRO) and the European ...

Time February 04, 2026
arrow
News | Radiology Imaging

Feb. 4, 2026 — The Royal College of Radiologists (RCR) has issued its initial reaction to the British government's ...

Time February 04, 2026
arrow
News | FDA

Jan. 29, 2026 — GE HealthCare has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) for MIM ...

Time February 03, 2026
arrow
News | Radiopharmaceuticals and Tracers

Jan. 29, 2026 — The American Society for Radiation Oncology (ASTRO) has launched a national program creating Authorized ...

Time January 30, 2026
arrow
News | Radiation Oncology

Jan. 27, 2026 — Researchers at the Icahn School of Medicine at Mount Sinai, in collaboration with other leading ...

Time January 29, 2026
arrow
News | PET Imaging

Jan. 26, 2026 — Nuclidium, a clinical-stage radiopharmaceutical company developing a proprietary copper-based ...

Time January 27, 2026
arrow
News | Radiology Imaging

Jan. 21, 2026 — Cathpax, a spin-off of the Lemer Pax group that designs, develops and commercializes team-wide, full ...

Time January 22, 2026
arrow
News | Radiation Therapy

Jan. 16, 2026 — Elekta has announced that its Elekta Evo* CT-Linac has received 510(k) clearance from the U.S. Food and ...

Time January 16, 2026
arrow
News | Radiopharmaceuticals and Tracers

Dec. 11, 2025 — Telix Pharmaceuticals Ltd. has announced a strategic clinical collaboration with Varian, a Siemens ...

Time December 11, 2025
arrow
News | FDA

Dec. 02, 2025 — Alpha Tau Medical Ltd., the developer of the alpha-radiation cancer therapy Alpha DaRT, has announced ...

Time December 04, 2025
arrow
Subscribe Now