News | January 14, 2015

UH Case Medical Center First to Offer Novel HeartFlow CT-FFR Technology

Non-invasive test determines impact of specific lesions on blood flow

HeartFlow, CT-FFR, computed tomography fractional flow reserve, UH Case Medical

Image courtesy of HeartFlow Inc.

January 14, 2015 — University Hospitals (UH) Case Medical is now offering a new, non-invasive test for coronary artery disease designed to help physicians develop the right treatment plan for each patient. Developed by HeartFlow Inc., computed tomography-fractional flow reserve (CT-FFR) is a non-invasive imaging technology specifically designed to offer insight on both the extent of the blockage, as well as whether it is impacting blood flow to the heart. UH Case Medical Center’s Daniel Simon, M.D., will be first to use the CT-FFR test in the United States.

Most other diagnostic tests are designed to provide information to clinicians regarding a patient’s overall risk of having coronary artery disease, but they cannot help the clinician determine the extent to which a specific blockage is impeding blood flow to the heart.

The CT-FFR platform was developed by marrying non-invasive 3-D imaging with computational fluid dynamics technology to produce detailed models of a patient’s cardiovascular anatomy. For every patient, CT-FFR performs millions of complex equations simulating blood flow in the coronary arteries to provide mathematically computed FFR values from images derived using non-invasive CT angiography. Fractional flow reserve values demonstrate blood pressure differences around a lesion to determine whether it is likely to reduce blood flow to the heart. These simulated values help physicians determine the right course of action for each patient. 

“CT-FFR represents a tremendous advancement in the diagnosis of coronary artery disease,” said Simon, president, Harrington Heart & Vascular Institute at UH Case Medical Center and Herman K. Hellerstein Chair and professor of medicine at Case Western Reserve University School of Medicine. “Historically, we have been faced with either using tests we knew were not always accurate or putting a patient through an invasive procedure just to determine whether they needed another invasive procedure. For the first time, we have access to a diagnostic that is both non-invasive and highly accurate in showing us the extent of a lesion, as well as how it can hinder blood flow through the vessel. I believe CT-FFR has the potential to completely change the way we manage coronary artery disease globally.”

Clinical data from the HeartFlow NXT study demonstrated superior discriminatory ability to identify lesions that have the potential to impede blood flow when compared to coronary CT angiography alone. In the study, published in the Journal of the American College of Cardiology in 2014, CT-FFR had higher diagnostic accuracy (86 percent) than coronary CT angiography (65 percent). This difference is primarily due to a significantly increased specificity with CT-FFR (86 percent) compared to coronary CT angiography (60 percent). Invasive angiography performed with 71 percent accuracy in the study.

With the improved data, patients will not have to undergo unnecessary procedures or further invasive or time-consuming testing associated with coronary artery disease.

For more information: www.heartflow.com

Related Content

Hospital for Special Surgery Invests in Sectra Orthopedic 3-D Planning Software
News | Orthopedic Imaging | January 18, 2018
January 18, 2018 – International medical imaging IT and cybersecurity company Sectra announces that Hospital for Spec
Philips Introduces Technology Maximizer Program for Imaging Equipment Upgrades
Technology | Imaging | January 17, 2018
January 17, 2018 — Philips recently announced the launch of Technology Maximizer, a cross-modality program designed t
Sponsored Content | Videos | Enterprise Imaging | January 16, 2018
Built on an over 25-year pioneering legacy in the advanced visualization industry, Vital continues to expand on three
RSNA 2017 Celebrates Innovation in Radiology
News | Imaging | January 15, 2018
January 15, 2018 — The Radiological Society of North America’s...
Fat Distribution in Women and Men Provides Clues to Heart Attack Risk
News | Women's Health | January 11, 2018
January 11, 2018 – It’s not the amount of fat in your body but where it is stored that may increase your risk for hea
Minimally Invasive Treatment Provides Relief from Back Pain

Lumbar spine MRI showing disc herniation and nerve root at baseline and one month after treatment

News | Interventional Radiology | January 11, 2018
The majority of patients were pain free after receiving a new image-guided pulsed radiofrequency treatment for low back...
Emergency Radiologists See Inner Toll of Opioid Use Disorders

Rates of Imaging Positivity for IV-SUDs Complications. Image courtesy of Efren J. Flores, M.D.

News | Clinical Study | January 11, 2018
January 11, 2018 – Emergency radiologists are seeing a high prevalence of patients with complications related to opio
CT Shows Enlarged Aortas in Former Pro Football Players

3-D rendering from a cardiac CT dataset demonstrating mild dilation of the ascending aorta.

News | Computed Tomography (CT) | January 11, 2018
Former National Football League (NFL) players are more likely to have enlarged aortas, a condition that may put them at...

Size comparison between 3-D printed prosthesis implant and a penny.

News | 3-D Printing | January 11, 2018
January 11, 2018 — Researchers using...
EchoPixel Showcases Next-Generation Surgical Planning With True 3-D Interactive Mixed Reality Software
News | Advanced Visualization | January 08, 2018
January 8, 2018 — EchoPixel showcased the latest version of True 3D, its interactive,...
Overlay Init