News | November 29, 2007

Study Sides with CADStream for Evaluation of Kinetics in Breast MRI

November 30, 2007 – Confirma announced that a study presented at RSNA found that the CADstream system’s patented “worst curve” algorithm for analyzing kinetics may assist in determining malignancy, concluding that any washout enhancement was associated with malignancy in nearly half of lesions.

The study, by the Seattle Cancer Care Alliance and the University of Washington, led by Dr. Lilian Wang, focused on the evaluation of kinetics and found that the most suspicious curve as identified by CADstream was significantly different between benign and malignant lesions. These findings support the recommendation of the American College of Radiology’s Breast Imaging Reporting and Database System (BI-RADS) Atlas for breast MRI to report the “worst looking” curve.

Entitled MRI Detected Suspicious Breast Findings: Comparison of Kinetic Features Measured by Computer-aided Evaluation in Benign and Malignant Lesion, the study examined 125 suspicious lesions (42 malignant, 83 benign) for which computer-aided-evaluation (CADstream) and subsequent image guided biopsy had been performed, out of a pool of 1538 breast MRI examinations conducted from November 2004 to November 2006.

The study compared three distinct computer-aided-evaluation kinetic features of suspicious breast MRI lesions to identify which may best predict benign or malignant outcomes, concluding that of the kinetic features analyzed only the most suspicious curve type as identified by CADstream was significantly different between benign and malignant lesions.

The CADstream system automates analysis, reporting and interventional planning of studies and promotes standardization with the incorporation of the American College of Radiology’s Breast Imaging Reporting and Database System (BI-RADS), which guides the breast cancer diagnostic routine and decision-making process. Confirma’s next-generation version of CADstream for breast MRI, launched this week at the RSNA meeting, includes a new customizable BI-RADS-centric user interface that accommodates a variety of user experience levels. Other CADstream enhancements include improved 3D renderings and tools for morphology reporting.

For more information: www.confirma.com

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