News | Radiopharmaceuticals and Tracers | October 19, 2015

Siemens’ PETNET Solutions to Produce Investigational PET Molecular Biomarker

Company to formulate exclusively for NuView Life Sciences VPAC1 molecular biomarker for prostate, breast cancer PET imaging clinical trials

Siemens PETNET Solutions, investigational PET molecular biomarker, prostate and breast cancer, PET/CT, PET/MR, NuView Life Sciences

Image courtesy of Philips

October 19, 2015 — Siemens’ PETNET Solutions Inc., a wholly owned subsidiary of Siemens Healthcare, will formulate the VPAC1 molecular biomarker 64Cu TP-3805 exclusively for clinical trials for the biopharmaceutical firm NuView Life Sciences Inc., of Park City, Utah.

Targeting the VPAC1 receptor over-expressed on the surface of malignant cancer cells, 64Cu TP-3805 is being studied for prostate and breast cancer imaging using positron emission tomography/computed tomography (PET/CT) and PET/magnetic resonance imaging (PET/MR).

Thomas Jefferson University and NuView developed a peptide that specifically binds to the VPAC1 receptor found on the surface of mutating cancer cells. The VPAC1 biomarker is a platform technology, for precision in-vivo cancer diagnosis, in-vitro cancer urine screening by identifying shed cancer cells in voided urine and may have application for precision cancer therapy delivery.

As a 64Cu-labeled peptide with a longer half-life (12.7 hours), 64Cu TP-3805 is better suited for clinical trial distribution across a large geographical area than other commonly used PET radiopharmaceuticals.

For more information: www.siemens.com, www.nuviewinfo.com

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