News | June 17, 2008

Radiation Dosage Based on BMI Advances Personalized Medicine

June 18, 2008 - In a new study presented at SNM’s 55th Annual Meeting, technologists are using body mass index (BMI), instead of body weight, to provide patients optimal dosing of 18-fluoro-2-deoxyglucose (FDG), a radiopharmaceutical commonly used in oncology imaging.

BMI is a calculation that takes into account both a patient’s weight and height. Traditionally, only a patient’s weight has been taken into consideration when prescribing appropriate dosage of radiopharmaceuticals for positron emission tomography (PET) and computed tomography (CT) scans.

“Using BMI allows us to more specifically adjust dosing to individual patients,” said Sarah Krumrey, a technologist in the Department of Nuclear Medicine at St. Louis University Hospital, St. Louis, Mo., and lead author of the study, Should FDG Dose Be Based on BMI Instead of Body Weight? presented at SNM’s 55th Annual Meeting, June 14–18 in New Orleans.

Current procedures for PET/CT scans with FDG use a patient’s weight as the main factor in determining the appropriate dose. The goal of this study was to compare changes in PET/CT image quality as a result of switching from a weight-adjusted to a BMI-adjusted FDG dose. A BMI-adjusted dose was used in a total of a 104 patients undergoing PET/CT exams for known or suspected cancer. In this double-blinded study, PET/CT scans were reviewed and graded to access the image quality. Switching to a BMI-adjusted dose resulted in improved image quality and lower required dosage of 18-FDG.

“Based on our study, we believe that adjusting the FDG dose according to a patient’s BMI could lead to new imaging protocols,” added Krumrey. “The results of this study—which takes into account individual patient factors—could further advance personalized medicine,” said Krumrey. “Unlike a blanket approach, this allows us to avoid unnecessary dosing and better treat the patients in our care.”

Scientific Paper 2010: S.A. Krumrey, I. Tran, P. Yost, D. Oliver, N. Nhuyen, M. Osman, F. Qazi, Nuclear Medicine, St. Louis University Hospital, St. Louis, Mo.: “Should FDG Dose Be Based on BMI Instead of Body Weight?” SNM’s 55th Annual Meeting, June 14–18, 2008.

For more information: visit

Related Content

International Working Group Releases New Multiple Myeloma Imaging Guidelines

X-ray images such as the one on the left fail to indicate many cases of advanced bone destruction caused by multiple myeloma, says the author of new guidelines on imaging for patients with myeloma and related disorders. Image courtesy of Roswell Park Comprehensive Cancer Center.

News | Computed Tomography (CT) | June 17, 2019
An International Myeloma Working Group (IMWG) has developed the first set of new recommendations in 10 years for...
BGN Technologies Introduces Novel Medical Imaging Radioisotope Production Method
News | Radiopharmaceuticals and Tracers | June 05, 2019
BGN Technologies, the technology transfer company of Ben-Gurion University (BGU), introduced a novel method for...
RefleXion Opens New Manufacturing Facility for Biology-guided Radiotherapy Platform
News | Radiation Therapy | May 31, 2019
RefleXion Medical recently announced the opening of its new manufacturing facility at its headquarters in Hayward,...
Siemens Healthineers Announces First U.S. Install of Biograph Vision PET/CT
News | PET-CT | March 06, 2019
Siemens Healthineers’ new Biograph Vision positron emission tomography/computed tomography (PET/CT) system has been...
News | PET-CT | February 06, 2019
Technological advancements in positron emission tomography/computed tomography (PET/CT) offer both clinicians and pat
FDA Clears United Imaging Healthcare uExplorer Total-Body Scanner
Technology | PET-CT | January 23, 2019
January 23, 2019 — United Imaging Healthcare (United Imaging) announced U.S.
Mirada Medical Joins U.K. Consortium Exploring Healthcare AI
News | Artificial Intelligence | December 04, 2018
Mirada Medical, a leading global brand in medical imaging software, will form part of an artificial intelligence (AI)...
Siemens Healthineers Showcases syngo Virtual Cockpit for More Flexible Workforce Management
News | Teleradiology | November 25, 2018
During the 104th Scientific Assembly and Annual Meeting of the Radiological Society of North America (RSNA), Nov. 25-30...
Bruker Introduces New High-Performance Preclinical PET/CT Si78 System
Technology | PET-CT | September 26, 2018
September 26, 2018 — Bruker recently announced the introduction of the new preclinical...