News | May 15, 2007

Positive Statistical Analysis from Synthetic Blood's Oxycyte Traumatic Brain Injury Trial

May 16, 2007 — Synthetic Blood International Inc. announced positive data from a statistical analysis of its Phase IIa study with Oxycyte in patients with traumatic brain injury. In line with preliminary study results announced in December 2006, statistical results confirmed that the primary endpoint of increasing patients' oxygen tension levels compared with baseline was met.

Data also show a decrease in patient glucose and lactate/pyruvate (LP) ratio, consistent with increased glucose metabolism. Patients in this trial were stabilized with either 50 percent or 100 percent oxygen. Data determined that results of both treatment arms were favorable, with statistically significant differences in some data between the two treatment arms.

"This analysis further validates our initial study findings that Oxycyte is more effective in increasing brain oxygen tension levels and impacting other brain chemistries that contribute to more favorable clinical outcomes in patients with traumatic brain injury, than breathing either 100 percent or 50 percent oxygen alone," said Robert Nicora, president and CEO. "Based on these positive results, we are working with Virginia Commonwealth University (VCU) to develop a protocol for a multicenter, controlled Phase IIb trial that could enroll up to 100 patients with traumatic brain injury. Researchers at VCU are drafting a manuscript with the Phase IIa TBI results to submit to a scientific journal.

"We continue active discussions with several sources for financing the company," Mr. Nicora continued. "If we are successful in these discussions, the receipt of additional funding will enable us to move forward with our Phase IIb program and other development activities with Oxycyte, which include plans to initiate a cardiac ischemia study in an animal model."

For more information visit www.sybd.com.

Related Content

ClearRead CT Nearing 50 Installations Milestone
News | Computed Tomography (CT) | June 22, 2017
June 22, 2017 — Riverain Technologies announced that it is now processing data from nearly 50...
Carestream Spotlights New Imaging Analytics Tools for Preventative Care at SIIM 2017, Clinical Collaboration Platform
News | Computer-Aided Detection Software | May 15, 2017
Carestream Health is demonstrating new imaging analytics tools that are being added to its Clinical Collaboration...
Low-Cost AI Could Screen for Cervical Cancer Better Than Humans
Feature | Artificial Intelligence | April 25, 2017
Artificial intelligence (AI) is already exceeding human abilities. Self-driving cars use AI to perform some tasks more...
Parascript and Volpara Establish Partnership for Improved Early Cancer Detection
News | Computer-Aided Detection Software | April 11, 2017
Parascript LLC announced a new partnership with Volpara Solutions, creator of Volpara Density automated breast density...
iCAD, PowerLook Tomo Detection, computer-aided detection software, CAD, digital breast tomosynthesis, DBT, RSNA 2017
Technology | Computer-Aided Detection Software | March 27, 2017
March 27, 2017 — iCAD announced that PowerLook Tomo Detection received Premarket Approval (PMA) from the U.S.
Parascript, AccuDetect CAD for Mammography, computer-aided detection, NCoBC 2017
News | Computer-Aided Detection Software | March 15, 2017
Parascript will exhibit at the National Consortium of Breast Centers (NCoBC) 27th Conference, March 11-17, 2017, in Las...
artificial intelligence, radiology, five reasons, Signify Research report
News | Artificial Intelligence | December 19, 2016
December 19, 2016 — A recent report from market research firm Signify Research presents five reasons why...
Sponsored Content | Videos | Artificial Intelligence | December 16, 2016
At RSNA 2016, the key buzzwords were “deep learning,” “machine learning” and “artificial intelligence.” Vendors and m
Sponsored Content | Videos | Artificial Intelligence | December 08, 2016
Mark Michalski, M.D., director of the Center for Clinical Data Science at Massachusetts General Hospital, explains th
Technology | Computer-Aided Detection Software | December 07, 2016
QView Medical Inc. announced that it received U.S. Food and Drug Administration (FDA) approval in early November for...
Overlay Init