News | June 17, 2008

PET/CT Scans May Determine Stages of Ovarian Cancer

June 18, 2008 - Using combined positron emission tomography (PET) and computed tomography (CT) scanning of patients in the early stages of ovarian cancer can enable physicians to determine whether the cancer has spread to nearby lymph nodes without having to perform surgery, according to researchers at the SNM's 55th Annual Meeting.

"Our preliminary research indicates that using PET/CT scanning in this way could greatly improve quality of life for many patients with ovarian cancer," said Luca Guerra, doctor of nuclear medicine, San Gerardo Hospital, Monza, Italy, and lead researcher of the study, 18F-FDG PET/CT Usefulness in Initial Staging of Ovarian Cancer. "PET/CT scans could allow many women to forego major abdominal surgery to determine whether their cancer has spread. It's a much safer alternative for determining the stages of ovarian cancer."

In their research, Guerra and his team examined results of 30 women diagnosed with ovarian cancer who underwent PET/CT scanning before surgery to determine the stage of their disease. The results indicated that PET/CT staging was correct in 67 percent of patients and more than 98 percent accurate in scanning the lymph nodes of stage I and stage II ovarian cancer patients. These very promising results need to be confirmed in a larger patient population.

While most previous studies that examined the potential of PET technologies have not indicated a definite role in the staging of ovarian cancer, many of the studies involved very small groups of women, and the scanners used were simple PET scanners rather than state-of-the-art, combined PET/CT scanners.

While systematic lymphadenectomy - surgically removing all of the lymph nodes for testing rather than sampling a small number of the lymph nodes - is more accurate in determining whether the cancer has spread, the surgery takes longer, often requires blood transfusions and can result in life-threatening complications. If all early-stage ovarian cancer patients underwent lymphadenectomy, approximately 75 percent of the surgeries would prove unnecessary.

For more information: www.snm.org

Related Content

SNMMI Publishes New FDG PET/CT Appropriate Use Criteria
News | PET-CT | October 25, 2017
The Society of Nuclear Medicine and Molecular Imaging (SNMMI) has published appropriate use criteria (AUC) for FDG PET/...
Majority of Recurrent Prostate Cancer Patients' Treatment Plan Changed Following Fluciclovine 18F PET/CT
News | Prostate Cancer | October 04, 2017
Blue Earth Diagnostics recently announced the results of a pre-planned interim analysis from an investigational...
Toshiba Highlights Latest CT Advancements at RSNA 2017
News | Computed Tomography (CT) | September 18, 2017
Toshiba Medical announced that it will display several new enhancements to its existing computed tomography (CT)...
Double Targeting Ligands to Identify and Treat Prostate Cancer

The mice were imaged with small-animal PET/CT using 124I-RPS-027 (7.4 MBq [200 μCi]). Credit: JM Kelly et al., Department of Radiology, Weill Cornell Medicine, New York, NY

News | Prostate Cancer | September 14, 2017
Researchers have demonstrated a new, effective way to precisely identify and localize prostate cancer tumors while...
Blue Earth Diagnostics Announcing Results of FALCON PET/CT Trial at ASTRO 2017
News | PET-CT | September 13, 2017
September 13, 2017 — Blue Earth Diagnostics announced the upcoming oral presentation of initial results from the FALC
FDG-PET/CT Predicts Melanoma Patients' Response to Immune Checkpoint Inhibitor Therapy
News | PET-CT | September 07, 2017
September 7, 2017 — Advanced melanoma has a poor prognosis, but immune checkpoint inhibitor therapy can be effective
Videos | Nuclear Imaging | August 24, 2017
Prem Soman, M.D., director of nuclear cardiology at the Heart and Vascular Institute, University of Pittsburgh, and p
ASNC and SNMMI Release Joint Document on Diagnosis, Treatment of Cardiac Sarcoidosis
News | Cardiac Imaging | August 18, 2017
August 18, 2017 — The American Society of Nuclear Cardiology (ASNC) has released a joint expert consensus document wi
PET/CT Tracer Identifies Vulnerable Lesions in Non-Small Cell Lung Cancer Patients

Example of a patient with an upper left lung NSCLC: A: FDG; B: FDG PET/CT; C: Planning radiotherapy based on FDG (66Gy) with BTVm (GTV), CTV and PTV; D: PET FMISO E: FMISO PET/CT; F: boost based on the FMISO PET (76Gy) with BTVh (biological hypoxic target volume) and PTV boost. Credit: QuantIF – LITIS EA 4108 – FR CNRS 3638, Henri Becquerel Cancer Center, Rouen, France

News | PET-CT | July 14, 2017
July 14, 2017 — Fluorine-18 (18F)-fluoromisonidazole (FMISO) is a positron emission tomography (PET)...
Overlay Init