News | Cardiovascular Ultrasound | June 19, 2019

LVivo EF Comparable to MRI, Contrast Echo in Assessing Ejection Fraction

Studies will be presented at the American Society of Echocardiography (ASE19) 30th Annual Scientific Session

LVivo EF Comparable to MRI, Contrast Echo in Assessing Ejection Fraction

June 19, 2019 — DiA Imaging Analysis announced the presentation of two studies assessing the performance and accuracy of the company's LVivo EF artificial intelligence (AI)-based solution that generates fully automated left ventricular ejection fraction (LVEF). EF is a main indicator in assessing the global function of the left ventricle. Presently, many readers quantify EF visually or trace endocardial borders that may not be well defined, yielding high variability among results. LVivo EF aims to substantially reduce this variability by generating objective, accurate and fast AI-based EF.

The studies were led by Martin Goldman, M.D., Solomon Bienstock, M.D., Rajeev Samtani, M.D., Steve Liao, M.D., Usman Baber, M.D., Arieh Greenbaum, M.D., Lori B. Croft, M.D., and Eric Stern, M.D., from Mount Sinai Hospital, New York.

The first study, "Validation of a Novel Artificial Intelligence Left Ventricular Ejection Fraction Quantification Software (LVivo EF by DIA) by Cardiac MRI,"1 tested the accuracy of the LVivo EF tool on 76 patients by retrospectively running it on cardiac four-chamber clips. The LVivo EF results were then compared to those obtained by magnetic resonance imaging (MRI) EF as a gold standard. The study indicated a strong correlation between cardiac MRI and LVivo EF (R2=0.89), and it suggests that LVivo EF may be used over a wide range of cardiac function, to evaluate EF in a fast and accurate manner.

"This study further validated DiA's AI-based tool, LVivo EF, against cardiac MRI EF, a recognized gold standard for the assessment of cardiac function. Based on the study's findings, LVivo EF has the potential to provide accurate and objective quantification of LVEF to support clinicians in the decision-making process, right at the patient's bedside, saving time and resources. This is specifically important in patients with low EF, where accuracy has clinical and therapeutic implications. Moreover, by providing the endocardial border overlay on the moving images, it also facilitates immediate confirmation of its accuracy by the reader," said Goldman, associate director of the CV Institute, director of the Fellowship Training Program and director of medical education at the Icahn School of Medicine at Mount Sinai Hospital.

The successful validation of LVivo EF as compared to MRI EF, led the team to publish a second study comparing LVivo EF results to physician's evaluation of EF using transthoracic echocardiography (TTE), with and without contrast agents, entitled "Fully Automated Echocardiographic Artificial Intelligence Software (LVivo EF by DiA) Could Replace Contrast Agents for Improving Accuracy of Left Ventricular Ejection Fraction Quantification." Results indicated that in non-contrast studies compared to cardiac MRI, LVivo EF was significantly better than physicians' assessments (R2=0.823 compared to R2=0.622), while for contrast studies, which are often used to improve LVEF analysis, LVivo EF on non-contrast images and physicians' quantification of contrast-enhanced images were similar (R2=0.913 and R2=0.873).

Both studies will be presented by Bienstock at the American Society of Echocardiography (ASE) 30th Annual Scientific Session, June 22-24 in Portland, Ore.

For more information: www.dia-analysis.com

Related Content

Paragon Biosciences Launches Qlarity Imaging to Advance FDA-cleared AI Breast Cancer Diagnosis System

Qlarity Imaging’s software is used to assist radiologists in the assessment and characterization of breast lesions. Imaging features are synthesized by an artificial intelligence algorithm into a single value, the QI score, which is analyzed relative to a database of reference abnormalities with known ground truth. Image courtesy of Business Wire.

Technology | Artificial Intelligence | July 18, 2019
Paragon Biosciences LLC announced the launch of its seventh portfolio company, Qlarity Imaging LLC, which was founded...
Two brain metastases from primary lung cancer are contrast enhanced in the brain of a 61-year-old male. Speakers at AHRA 2019 will state that ProHance and other macrocyclic MR agents present a very low risk to patients. Images courtesy of Bracco

Two brain metastases from primary lung cancer are contrast enhanced in the brain of a 61-year-old male. Speakers at AHRA 2019 will state that ProHance and other macrocyclic MR agents present a very low risk to patients. Images courtesy of Bracco

Feature | Contrast Media | July 18, 2019 | By Greg Freiherr
Macrocyclic contrast agents have the best safety profile of all the magnetic resonance (MR) contrast media that are n
AAPM 2019 Features More Than 40 Presentations on ViewRay's MRIdian MRI-guided Radiotherapy
News | Image Guided Radiation Therapy (IGRT) | July 16, 2019
ViewRay Inc. announced that the company's MRIdian System is the focus of more than 40 abstracts selected by the...
FDA Approves Bayer's Gadavist Contrast for Cardiac MRI in Adult Coronary Artery Disease Patients
Technology | Contrast Media | July 15, 2019
The U.S. Food and Drug Administration (FDA) has approved Gadavist injection for use in cardiac magnetic resonance...
Graphic courtesy Pixabay

Graphic courtesy Pixabay

Feature | Artificial Intelligence | July 15, 2019 | By Greg Freiherr
Siemens has long focused on automation as a way to make diagnostic equipment faster and more efficient.
Videos | Artificial Intelligence | July 12, 2019
Khan Siddiqui, M.D., founder and CEO of HOPPR, discusses the economic advantages and costs presented by...
Videos | Digital Pathology | July 11, 2019
Toby Cornish, M.D., Ph.D., associate professor and medical director of informatics at the University of Colorado Scho
FDA Clears Koios DS Breast 2.0 AI-based Software
News | Ultrasound Women's Health | July 11, 2019
Koios Medical announced its second 510(k) clearance from the U.S. Food and Drug Administration (FDA).