News | Prostate Cancer | August 20, 2019

Improved Imaging Technique Could Increase Chances of Prostate Cancer Survival

Grant will enable imaging advances to improve diagnosis of prostate cancer

Improved Imaging Technique Could Increase Chances of Prostate Cancer Survival

August 20, 2019 — According to the American Cancer Society, approximately one in nine men will be diagnosed with prostate cancer in their lifetime. It’s both the second most common cancer and second most common cause of cancer death in American men. Early detection is critical and can increase a man’s chances of survival.

“Imaging has become an essential component of modern medicine,” said Pingkun Yan, assistant professor of biomedical engineering at Rensselaer Polytechnic Institute. “I believe it will become more and more important with precision medicine. If you use imaging together with other techniques, you can actually better customize a treatment for a specific patient.”

Yan recently received the latest in a series of grants — totaling more than $1 million combined — aimed at advancing current imaging technology, and developing new tools for diagnosis and treatment delivery. The most recent award, from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), will help him improve an image fusion technique — currently used clinically to enable biopsies for diagnosis — without external tracking devices.

Right now, Yan said, magnetic resonance (MR) imaging produces pictures that help identify the cancer. That information is then combined with transrectal ultrasound imaging, which helps guide the biopsy. Though this can work fairly well when done properly, combining these two imaging modalities is difficult and is open to error. An additional tracking device is required that is both expensive and cumbersome, and any patient movement that causes the prostate to change position makes the fused images unreliable.

Using a deep learning approach, Yan plans to simplify the process. He wants medical personnel to be able to see the MR image that identifies the cancer while they are using the ultrasound to guide the biopsy, without using additional tracking devices.

“Although we target a specific application, the technology we are developing can be applied to many different applications,” Yan said. “For example, you would be able to fuse ultrasound and CT [computed tomography] images to guide a liver biopsy, liver cancer treatment or kidney cancer biopsy.”

Yan is also a member of the Bioimaging Center and Cancer Research Group (CARGO) based within the Rensselaer Center for Biotechnology and Interdisciplinary Studies (CBIS).

“Imaging is an essential key to our understanding, diagnosis, and treatment of disease,” said Deepak Vashishth, director of CBIS. “This foundational research that Professor Yan is doing will enable the next generation of imaging technology and help provide a new angle on cancer.”

For more information: www.rpi.edu

Related Content

The Caption Guidance software uses artificial intelligence to guide users to get optimal cardiac ultrasound images in a point of care ultrasound (POCUS) setting.

The Caption Guidance software uses artificial intelligence to guide users to get optimal cardiac ultrasound images in a point of care ultrasound (POCUS) setting.

News | Artificial Intelligence | February 13, 2020
February 13, 2020 — The U.S.
Hyperfine Research, Inc. announced that it has received U.S. Food and Drug Administration (FDA) 510(k) clearance for the world’s first bedside Magnetic Resonance Imaging (MRI) system

Hyperfine's point-of-care MRI wheels directly to the patient’s bedside, plugs into a standard electrical wall outlet, and is controlled via a wireless tablet. Photo courtesy of Business Wire

News | Magnetic Resonance Imaging (MRI) | February 12, 2020
February 12, 2020 — Hyperfine Research, Inc. announced that i
The magnetic resonance imaging (MRI) contrast agents market is expected to grow rapidly

Image courtesy of GE Healthcare

News | Magnetic Resonance Imaging (MRI) | February 11, 2020
February 11, 2020 — The magnetic resonance imaging (MRI) contrast agents market is expected to grow rapidly in the fo
Gadolinium-based contrast agents

UT Dallas faculty members who collaborated with Dr. Jeremiah Gassensmith (center, back), associate professor of chemistry and biochemistry, include Dr. Lloyd Lumata (left, back), assistant professor of physics, and Dr. Steven Nielsen, associate professor of chemistry. Chemistry graduate students in Gassensmith’s lab include (from left, front) Oliva Brohlin, Arezoo Shahrivarkevishahi and Laurel Hagge.

News | Contrast Media | February 06, 2020
February 6, 2020 — University of Texas at Dallas researchers
Qynapse, a medical technology company, announced that it received U.S. Food and Drug Administration (FDA) 510(k) clearance for its QyScore software
News | Information Technology | February 04, 2020
February 4, 2020 — Qynapse, a medical technology company, anno
RSNA 2019

RSNA 2019

Feature | Radiology Imaging | January 31, 2020 | By Greg Freiherr
The founder of Gonzo journalism thought
This image is of an 80 kg woman with a newly diagnosed IDH-wildtype glioblastoma

This image is of an 80 kg woman with a newly diagnosed IDH-wildtype glioblastoma. The quarter dose image on the left was obtained after the administration of 4 ml of MultiHance. Subsequently, an additional 12 ml of MultiHance was administered and the cumulative full dose image in the center was obtained. The image on the right was rendered following artificial intelligence processing of the 4 ml image using eGad genetic algorithms. This image has the quality of triple dose gadolinium even though only one quarter dose gadolinium was given.

Feature | Contrast Media Injectors | January 30, 2020 | By Matthew Kuhn, M.D., FACR
Gadolinium-based contrast agents (...
Automated Triage of Thyroid Cancer

73-year-old man with papillary carcinoma of left lobe of thyroid. Screen shot shows example of thyroid nodule annotation (segmentation and TI-RADS annotation) performed on ultrasound image in longitudinal projection with electronic Physician Annotation Device software (Stanford Medicine Radiology). Radiologists performed nodule segmentation by selecting points (red) on nodule outline (green), while controlling smoothing of outline polygon by means of spline interpolation.

News | Ultrasound Imaging | January 30, 2020
January 30, 2020 — According to an ar...
The researchers used high resolution cross-sectional imaging with CT or MRI to assess 225 men with abdominal aortic aneurysm. Follow-up lasted, on average, more than three years.  Slightly more than half of patients had an intraluminal thrombus. The aneurysms of those with intraluminal thrombus were larger at baseline and grew by a rate of 2 mm per year, twice as fast as the 1 mm per year growth rate in people without intraluminal thrombus.
News | Computed Tomography (CT) | January 29, 2020
January 29, 2020 – The presence of a blood clot on the wall of the aorta in people with...
This is a lung X-ray reviewed automatically by artificial intelligence (AI) to identify a collapsed lung (pneumothorax) in the color coded area. This AI app from Lunit is awaiting final FDA review and in planned to be integrated into several vendors' mobile digital radiography (DR) systems. Fujifilm showed this software integrated as a work-in-progress into its mobile X-ray system at RSNA 2019. GE Healthcare has its own version of this software for its mobile r=ray systems that gained FDA in 2019.   #RSNA #

This is a lung X-ray reviewed automatically by artificial intelligence (AI) to identify a collapsed lung (pneumothorax) in the color coded area. This AI app from Lunit is awaiting final FDA review and in planned to be integrated into several vendors' mobile digital radiography (DR) systems. Fujifilm showed this software integrated as a work-in-progress into its mobile X-ray system at RSNA 2019. GE Healthcare has its own version of this software for its mobile r=ray systems that gained FDA in 2019.

Feature | RSNA | January 20, 2020 | Dave Fornell, Editor
Here are images of some of the newest new medical imaging technologies displayed on the expo floor at the ...