News | December 06, 2006

GE, Pitt Study Amyloid Deposits in Alzheimer’s Patients

A key milestone in the imaging of Alzheimer’s Disease has been reached by radiochemists from the University of Pittsburgh and GE Healthcare. The university is conducting a study aimed at obtaining preliminary information on the performance of flourine-18 labelled Pittsburgh Compound B (F-18 PiB) to identify amyloid deposits in subjects with a diagnosis of Alzheimer’s. Early results are encouraging, researchers said.

Although C-11 PiB can be used for academic studies, the 20-minute half-life of C-11 and limited manufacturing access means the molecule is not suitable for widespread use as a routine diagnostic agent. F-18, with a half-life of 110 minutes, offers a much better opportunity for manufacturing and distribution.

In 2003, GE Healthcare licensed a number of compounds from the University of Pittsburgh. Proof of concept studies have already been performed in collaboration with GE Healthcare’s IMANET organization, leading to the selection of the lead candidate for further research. Subsequent work has focused on producing the F-18 PiB material to the quality standards necessary for clinical trial use.

Related Content

ClearRead CT Nearing 50 Installations Milestone
News | Computed Tomography (CT) | June 22, 2017
June 22, 2017 — Riverain Technologies announced that it is now processing data from nearly 50...
Carestream Spotlights New Imaging Analytics Tools for Preventative Care at SIIM 2017, Clinical Collaboration Platform
News | Computer-Aided Detection Software | May 15, 2017
Carestream Health is demonstrating new imaging analytics tools that are being added to its Clinical Collaboration...
Low-Cost AI Could Screen for Cervical Cancer Better Than Humans
Feature | Artificial Intelligence | April 25, 2017
Artificial intelligence (AI) is already exceeding human abilities. Self-driving cars use AI to perform some tasks more...
Parascript and Volpara Establish Partnership for Improved Early Cancer Detection
News | Computer-Aided Detection Software | April 11, 2017
Parascript LLC announced a new partnership with Volpara Solutions, creator of Volpara Density automated breast density...
iCAD, PowerLook Tomo Detection, computer-aided detection software, CAD, digital breast tomosynthesis, DBT, RSNA 2017
Technology | Computer-Aided Detection Software | March 27, 2017
March 27, 2017 — iCAD announced that PowerLook Tomo Detection received Premarket Approval (PMA) from the U.S.
Parascript, AccuDetect CAD for Mammography, computer-aided detection, NCoBC 2017
News | Computer-Aided Detection Software | March 15, 2017
Parascript will exhibit at the National Consortium of Breast Centers (NCoBC) 27th Conference, March 11-17, 2017, in Las...
artificial intelligence, radiology, five reasons, Signify Research report
News | Artificial Intelligence | December 19, 2016
December 19, 2016 — A recent report from market research firm Signify Research presents five reasons why...
Sponsored Content | Videos | Artificial Intelligence | December 16, 2016
At RSNA 2016, the key buzzwords were “deep learning,” “machine learning” and “artificial intelligence.” Vendors and m
Sponsored Content | Videos | Artificial Intelligence | December 08, 2016
Mark Michalski, M.D., director of the Center for Clinical Data Science at Massachusetts General Hospital, explains th
Technology | Computer-Aided Detection Software | December 07, 2016
QView Medical Inc. announced that it received U.S. Food and Drug Administration (FDA) approval in early November for...
Overlay Init