News | February 09, 2012

Boston Scientific WallFlex Enteral Stents Safe, Effective in Three Clinical Registries

February 9, 2012 — Boston Scientific announced positive results from three studies of the WallFlex enteral stent systems, a family of self-expanding metal stents (SEMS) used to alleviate obstructive symptoms caused by cancers of the gastrointestinal tract.  The studies, published in peer-reviewed medical journals, determined the WallFlex stents to be safe and effective for the treatment of malignant colorectal and gastroduodenal obstruction.  

The first publication appeared in the October 2011 issue of Gastrointestinal Endoscopy, and reported the short-term safety and effectiveness of the Boston Scientific WallFlex enteral colonic stent for relieving malignant colorectal obstruction.  This 447-patient study represents the largest prospective, multi-center series to date of colonic SEMS placement in both palliative and bridge-to-surgery settings. The WallFlex Enteral colonic stent was determined to be safe and effective for treatment of malignant colorectal obstruction with a clinical success rate of 90.5 percent.  The authors determined that SEMS allowed most bridge-to-surgery patients to have an elective surgical procedure without a colostomy and most incurable patients to receive minimally invasive palliation instead of surgery.

"Based on results from this study, physicians should consider SEMS as a first-line treatment option for patients with malignant colorectal obstruction," said Soren Meisner, M.D., of Bispebjerg Hospital in Copenhagen, Denmark and principal author of the study.  "SEMS provide patients with a less-invasive alternative to surgery and may also improve quality of life."

The second publication, appearing in the December 2011 issue of The American Journal of Gastroenterology, reports on 182 patients from the WallFlex colonic stent registries that received a WallFlex colonic stent as a bridge to surgery.  Findings show rates of 97.8 percent procedural success and 94 percent clinical success, prompting the authors to conclude that the stent is both safe and effective as a bridge-to-surgery treatment in patients with acute malignant obstruction.

The third publication were the results from the international, multi-center WallFlex duodenal stent registry and were published in the January 2012 issue of Digestive and Liver Disease.  The largest prospective study of its kind assessed the treatment of malignant gastroduodenal obstruction in 202 patients.  Results confirmed the safety and effectiveness of the WallFlex enteral duodenal stent, which demonstrated procedural and clinical success rates of 98 and 91 percent, respectively.  The authors concluded that adoption of duodenal stenting could result in this minimally invasive procedure becoming standard of care when managing inoperable patients with advanced cancer experiencing gastric outlet obstruction.

For more information: www.bostonscientific.com

Related Content

Stereotactic Radiosurgery Effective for Pediatric Arteriovenous Malformation Patients
News | Radiation Therapy | April 19, 2019
Ching-Jen Chen, M.D., of the neurosurgery department at the University of Virginia (UVA) Health System, was the winner...
Video Plus Brochure Helps Patients Make Lung Cancer Scan Decision

Image courtesy of the American Thoracic Society

News | Lung Cancer | April 19, 2019
A short video describing the potential benefits and risks of low-dose computed tomography (CT) screening for lung...
Surgically Guided Brachytherapy Improves Outcomes for Intracranial Neoplasms
News | Brachytherapy Systems | April 18, 2019
Peter Nakaji, M.D., FAANS, general practice neurosurgeon at Barrow Neurological Institute, presented new research on...
Check-Cap Initiates U.S. Pilot Study of C-Scan for Colorectal Cancer Screening
News | Colonoscopy Systems | April 15, 2019
Check-Cap Ltd. has initiated its U.S. pilot study of the C-Scan system for prevention of colorectal cancer through...
Ethicon Launches Global Liver Lesion Ablation Registry
News | Interventional Radiology | April 10, 2019
Johnson & Johnson Medical Devices Companies announced Ethicon has launched a new global registry to collect and...
Deep Lens Closes Series A Financing for Digital AI Pathology Platform
News | Digital Pathology | April 09, 2019
Digital pathology company Deep Lens Inc. announced the closing of a $14 million Series A financing that will further...
Society of Interventional Radiology Announces 2019 Gold Medalists
News | Interventional Radiology | April 08, 2019
The Society of Interventional Radiology (SIR) presented its highest honor, the SIR Gold Medal, to Alan H. Matsumoto, M....
Uterine Fibroid Embolization Safer and as Effective as Surgical Treatment
News | Interventional Radiology | April 05, 2019
Uterine fibroid embolization (UFE) effectively treats uterine fibroids with fewer post-procedure complications compared...
Videos | RSNA | April 03, 2019
ITN Editor Dave Fornell takes a tour of some of the most interesting new medical imaging technologies displa