The first randomized trial investigating the additional value of magnetic resonance imaging (MRI) for screening women with dense breasts, is featured in the current issue of Radiology. The article, “MR Imaging as an Additional Screening Modality for the Detection of Breast Cancer in Women Aged 50–75 Years with Extremely Dense Breasts: The DENSE Trial Study Design,†presents the rationale and design of the DENSE Trial. Run by Carla van Gils, M.D., and Wouter Veldhuis, M.D., from University Medical Center Utrecht (UMCU) in the Netherlands, the trial seeks to determine the effectiveness of screening with mammography and MRI compared to mammography alone in women who have extremely dense breasts.