News | Radiation Oncology | February 22, 2024

Clinical trials will assess multi-cancer detection tests, among others

Clinical trials will assess multi-cancer detection tests, among others

Getty Images


February 22, 2024 — The National Institutes of Health has launched a clinical trials network to evaluate emerging technologies for cancer screening. The Cancer Screening Research Network (CSRN) will support the Biden-Harris administration’s Cancer Moonshot by investigating how to identify cancers earlier, when they may be easier to treat. Eight groups have received funding from the National Cancer Institute (NCI), part of NIH, to carry out the initial activities of the network.

“There are many cancers we still cannot reliably detect until it is so late that they become extremely difficult to treat,” said W. Kimryn Rathmell, M.D., Ph.D., director of NCI. “Emerging technologies such as multi-cancer detection tests could transform cancer screening and help to extend the lives of many more people. We need to be sure that these technologies work and understand how to use them so they benefit everyone.”

Studies are needed, for example, to evaluate the benefits and harms of promising new technologies for cancer screening and to determine how best to incorporate these technologies into the standard of care.

In 2024, the network will launch a pilot study, known as the Vanguard Study on Multi-Cancer Detection, to address the feasibility of using multi-cancer detection (MCD) tests in future randomized controlled trials. MCDs are blood tests that can screen for several types of cancers. The study will enroll up to 24,000 people to inform the design of a much larger randomized controlled trial. This larger trial will evaluate whether the benefits of using MCD tests to screen for cancer outweigh the harms, and whether they can detect cancer early in a way that reduces deaths.

“Our goal is to systematically evaluate cancer screening technologies to understand how best to use them to ultimately save lives. Data collected through these clinical trials can be used to develop evidence-based guidelines for cancer screening,” said Lori M. Minasian, M.D., deputy director of the Division of Cancer Prevention at NCI.

In its studies, the network aims to reach diverse populations that are receiving routine care in a variety of health care settings. Study sites are geographically diverse and include underserved populations. Study investigators will come from a variety of disciplines that are actively engaged in cancer screening.

“We want to ensure that the organizations involved in this network will also be recruiting from populations historically underrepresented in clinical trials, which will make the data we generate as representative as possible,” Dr. Minasian said. “It is important to make sure that these new technologies benefit all Americans.”

Initial funding will provide resources for study coordination, communication activities, statistics and data management, and accrual and enrollment of participants into clinical trials and studies. Fred Hutchinson Cancer Center in Seattle will serve as the network’s coordinating and communications center and the statistics and data management center.

The seven additional funded sites will lead efforts to enroll participants in their geographic and coverage areas and include:

The Department of Defense Uniformed Services University and the Department of Veterans Affairs will also participate as sites funded by their respective agencies.

For more information: www.nih.gov


Related Content

News | Radiation Therapy

April 18, 2024 — Accuray Incorporated announced that as part of its commitment to advancing patient care the company has ...

Time April 18, 2024
arrow
News | FDA

April 18, 2024 — Lumicell, Inc., a privately held company focused on developing innovative fluorescence-guided imaging ...

Time April 18, 2024
arrow
News | Lung Imaging

April 17, 2024 — A Medicare policy requiring primary care providers (PCPs) to share in the decision-making with patients ...

Time April 17, 2024
arrow
News | Mammography

April 12, 2024 — Bayer and Hologic, Inc. announced a first-of-its-kind collaboration to deliver a coordinated solution ...

Time April 12, 2024
arrow
News | Mammography

April 12, 2024 — GE HealthCare, a leader in breast health technology and diagnostics, will feature its latest breast ...

Time April 12, 2024
arrow
News | Radiation Therapy

April 12, 2024 — RTsafe, a leading provider of quality assurance products and services in stereotactic radiosurgery, and ...

Time April 12, 2024
arrow
News | Artificial Intelligence

April 9, 2024 —PreciseDx, a leading innovator in oncology diagnostics leveraging Artificial Intelligence (AI) for ...

Time April 09, 2024
arrow
News | Artificial Intelligence

April 8, 2024 — Lunit, a leading provider of AI-powered solutions for cancer diagnostics and therapeutics, today ...

Time April 08, 2024
arrow
Feature | Radiology Business | By Melinda Taschetta-Millane

Here is a snapshot of the Top 10 most-read content from ITN's viewers during the month of March: 1. Philips Teams with ...

Time April 04, 2024
arrow
News | Artificial Intelligence

March 28, 2024 — As artificial intelligence (AI) makes its way into cancer care – and into discussions between ...

Time March 28, 2024
arrow
Subscribe Now