News | September 13, 2011

Mediso Introduces First Integrated Whole-Body Preclinical PET/MRI Imager

Mediso Introduces First Integrated Whole-Body Preclinical PET/MRI Imager

September 13, 2011 – Mediso Medical Imaging Systems announced at the World Molecular Imaging Congress (WMIC) the launching of the new nanoScan positron emission tomography/magnetic resonance imaging (PET/MRI), in vivo molecular and preclinical imager.

The PET subsystem, equipped with the new Tera-Tomo 3-D reconstruction engine, performs quantitative PET studies with an average resolution of 700 microns. Due to the advanced graphics processing unit (GPU) based on the fly system matrix generation principle and the physical corrections in 3-D PET reconstruction, a uniform resolution is achieved throughout the field-of-view.

Using corrections for a variety of physical factors, a quantitative three-dimensional PET reconstruction has been developed and applied by Mediso and their academic collaborators. Some of these factors include detector response, detector attenuation and scatter, object attenuation and scatter, random, dead time and positron range.

The compact shielded MRI platform from Aspect imaging utilizes a high-performance 1T magnet with zero magnetic fringe field outside the magnet. It provides high spatial resolution of down to 100 micrometers (?m), with high soft tissue contrast required for anatomical/morphological imaging. The permanent magnet platform provides a maintenance-free MRI solution with a small footprint and easy installation. It is optimized to perform fast, high-throughput imaging of a variety of applications and preclinical studies.

The new platform can be applied for imaging and quantification in the following areas: oncology and tumor biology, regenerative medicine, PET development of radiotracers, receptor studies in neuroscience, inflammation and immunology, infectious diseases, animal model development and phenotyping and multi- modal imaging and contrast agent development.

The system is designed for any facility and for use by any operator. There is no need for any additional magnetic or RF shielding and no special site preparation is required for the installation of the equipment.

The first device was installed at the prestigious Karolinska Institute in April 2011 and is being used by Prof. Christer Halldin and in the core imaging laboratories of Professor Balázs Gulyás. It was the optimal imaging choice for Halldin, whose research requires the highest level PET radiotracer technology along with support and co-registration with high-resolution MRI images.

“The nanoScan PM combines anatomical and molecular imaging modalities using a state-of-the-art PET technology with cutting edge resolution and sensitivity and a unique user friendly MRI imaging for pre-clinical studies,” says Halldin, professor, director of Karolinska Institute PET Center.

For more information: www.mediso.com

Related Content

A high-fidelity 3-D tractography of the left ventricle heart muscle fibers of a mouse

Figure 1. A high-fidelity 3-D tractography of the left ventricle heart muscle fibers of a mouse from Amsterdam Ph.D. researcher Gustav Strijkers.

News | Magnetic Resonance Imaging (MRI) | June 07, 2019
The Amsterdam University Medical Center has won MR Solutions’ Image of the Year 2019 award for the best molecular...
Study Explores Magnetic Nanoparticles as Bimodal Imaging Agent for PET/MRI

Image courtesy of MR Solutions.

News | PET-MRI | May 23, 2019
Researchers from Bourgogne University in Dijon, France, showed that use of superparamagnetic iron oxide nanoparticles (...
Siemens Healthineers Demonstrates Artificial Intelligence, Healthcare Digitalization at HIMSS19
News | Artificial Intelligence | February 13, 2019
February 13, 2019 — At the 2019 Healthcare Information and Management Systems Society (HIMSS) global conference and e
Siemens Healthineers Showcases syngo Virtual Cockpit for More Flexible Workforce Management
News | Teleradiology | November 25, 2018
During the 104th Scientific Assembly and Annual Meeting of the Radiological Society of North America (RSNA), Nov. 25-30...
Huntsman Cancer Institute Installs First Preclinical nanoScan 3T PET/MRI in U.S.
News | PET-MRI | October 10, 2018
The Center for Quantitative Cancer Imaging at Huntsman Cancer Institute (HCI) at the University of Utah in Salt Lake...
Axumin PET Agent Added to NCCN Guidelines for Suspected Recurrent Prostate Cancer
News | PET Imaging | February 21, 2018
Blue Earth Diagnostics announced that Axumin (fluciclovine F 18) injection has been added to the National Comprehensive...
News | Radiology Business | September 19, 2017
September 19, 2017 — Invicro LLC, a provider of imaging services and software for research and drug development, anno
Dual-Agent PET/MR With Time of Flight Detects More Cancer

Tc-99m MDP bone scan (left) is negative for osseous lesions. NaF/FDG PET/MRI (right and second slide) confirms absence of bone metastases, but shows liver metastases. Image courtesy of Stanford University.

News | PET-MRI | June 20, 2017
Simultaneous injections of the radiopharmaceuticals fluorine-18 fluorodeoxyglucose (18F-FDG) and 18F-sodium fluoride (...