News | Breast Imaging | October 26, 2016

ECOG-ACRIN Begins Site Recruitment for TMIST Breast Imaging Trial

Four-year study comparing tomosynthesis to standard digital mammography will enroll 165,000 asymptomatic women in the United States and Canada

ECOG-ACRIN, TMIST, Tomosynthesis Mammography Imaging Screening Trial, site recruitment, RSNA 2016

October 26, 2016 — The Tomosynthesis Mammography Imaging Screening Trial (TMIST), the first large-scale breast cancer screening trial in nearly 25 years, has been approved for funding by the National Cancer Institute (NCI). The ECOG-ACRIN Cancer Research Group (ECOG- ACRIN) leading the trial is now recruiting medical facilities as it prepares to open the trial in mid-2017.

TMIST will enroll 165,000 asymptomatic women in the United States and Canada between the ages of 45 and 74 to compare the incidence of advanced cancers in those screened for four years with digital breast tomosynthesis versus standard digital mammography. The study aims to provide a modern basis for the continued use of mammography for breast cancer screening.

Interested medical imaging providers can attend one of two TMIST informational sessions while at the upcoming Radiological Society of North America (RSNA) annual meeting, Nov. 27-Dec. 3 in Chicago.

To participate in TMIST, a medical facility must be (1) located in the U.S. or Canada, (2) able to provide both imaging methods in the same location, and (3) a member of a research group in the NCI National Clinical Trials Network (NCTN), either directly or through the NCI Community Oncology Research Program (NCORP). TMIST will require nearly 100 sites, estimating that each will enroll about four to five women per day to reach the accrual goal in about three years.

TMIST image acquisition, storage and sharing will be carried out at the American College of Radiology (ACR) Center for Research and Innovation. Constantine A. Gatsonis, Ph.D., at the ECOG-ACRIN Biostatistics and Data Management Center at Brown University Center for Statistician Sciences, will lead the TMIST statistical analysis.

The NTCN research groups are the Alliance for Clinical Trials in Oncology, Canadian Cancer Clinical Trials Network, ECOG-ACRIN Cancer Research Group, NRG Oncology, and SWOG.

For more information: www.ecog-acrin.org

Related Content

EMR patient portal on a smartphone
News | Electronic Medical Records (EMR) | December 11, 2019
December 11, 2019 — Despite the numerous benefits associated with patients accessing their medical records, a new stu
Damage from concussion alters the way information is transmitted between the two halves of the brain, according to a new study presented today at the annual meeting of the Radiological Society of North America (RSNA).

Image courtesy of RSNA

News | Clinical Trials | December 10, 2019
December 10, 2019 — Damage from...
After receiving acupuncture treatment three days a week during the course of radiation treatment, head and neck cancer patients experienced less dry mouth, according to study results from researchers at The University of Texas MD Anderson Cancer Center

Image by Rudolf Langer from Pixabay 

News | Clinical Trials | December 06, 2019
December 6, 2019 — After receiving acupuncture treatment three days a week during the course of...
Timothy Whelan is a professor of oncology at McMaster University and a radiation oncologist at the Juravinski Cancer Centre of Hamilton Health Sciences. He holds a Canada Research Chair in Breast Cancer Research. Photo courtesy McMaster University

Timothy Whelan is a professor of oncology at McMaster University and a radiation oncologist at the Juravinski Cancer Centre of Hamilton Health Sciences. He holds a Canada Research Chair in Breast Cancer Research. Photo courtesy McMaster University. Photo courtesy of McMaster University

News | Breast Imaging | December 06, 2019
December 6, 2019 — A shorter course of higher-dose radiation treatment to part of the breast is showing promise in wo
MRI Exablate neuro helmet from INSIGHTEC

MRI Exablate neuro helmet from INSIGHTEC. Image courtesy of Ali Rezai, M.D., and RSNA.

News | Clinical Trials | December 03, 2019
December 3, 2019 — Focused ultrasound is a safe and effective way to target and open areas of the blood-brain barrier
Image by Kira Hoffmann from Pixabay  #RSNA19

Image by Kira Hoffmann from Pixabay 

News | Clinical Trials | November 30, 2019
November 30, 2019 — Researchers are trying to identify injury patterns and predict future outcomes for victims of gun
#RSNA19 GE Healthcare introduced Serena Bright, the healthcare industry’s first contrast-enhanced mammography solution for biopsy
News | Mammography | November 30, 2019
November 30, 2019 — To help empower clinicians and patients in their fight against...
This bar graph shows breast cancer presentation by screening interval #RSNA19

This bar graph shows breast cancer presentation by screening interval. Image courtesy of study author and RSNA

News | Breast Imaging | November 28, 2019
November 28, 2019 — Cancers found in patients undergoing annual...