News | Breast Imaging | October 26, 2016

ECOG-ACRIN Begins Site Recruitment for TMIST Breast Imaging Trial

Four-year study comparing tomosynthesis to standard digital mammography will enroll 165,000 asymptomatic women in the United States and Canada

ECOG-ACRIN, TMIST, Tomosynthesis Mammography Imaging Screening Trial, site recruitment, RSNA 2016

October 26, 2016 — The Tomosynthesis Mammography Imaging Screening Trial (TMIST), the first large-scale breast cancer screening trial in nearly 25 years, has been approved for funding by the National Cancer Institute (NCI). The ECOG-ACRIN Cancer Research Group (ECOG- ACRIN) leading the trial is now recruiting medical facilities as it prepares to open the trial in mid-2017.

TMIST will enroll 165,000 asymptomatic women in the United States and Canada between the ages of 45 and 74 to compare the incidence of advanced cancers in those screened for four years with digital breast tomosynthesis versus standard digital mammography. The study aims to provide a modern basis for the continued use of mammography for breast cancer screening.

Interested medical imaging providers can attend one of two TMIST informational sessions while at the upcoming Radiological Society of North America (RSNA) annual meeting, Nov. 27-Dec. 3 in Chicago.

To participate in TMIST, a medical facility must be (1) located in the U.S. or Canada, (2) able to provide both imaging methods in the same location, and (3) a member of a research group in the NCI National Clinical Trials Network (NCTN), either directly or through the NCI Community Oncology Research Program (NCORP). TMIST will require nearly 100 sites, estimating that each will enroll about four to five women per day to reach the accrual goal in about three years.

TMIST image acquisition, storage and sharing will be carried out at the American College of Radiology (ACR) Center for Research and Innovation. Constantine A. Gatsonis, Ph.D., at the ECOG-ACRIN Biostatistics and Data Management Center at Brown University Center for Statistician Sciences, will lead the TMIST statistical analysis.

The NTCN research groups are the Alliance for Clinical Trials in Oncology, Canadian Cancer Clinical Trials Network, ECOG-ACRIN Cancer Research Group, NRG Oncology, and SWOG.

For more information: www.ecog-acrin.org

Related Content

Bay Labs and Northwestern Medicine Enroll First Patient in AI Echocardiography Study
News | Cardiovascular Ultrasound | November 19, 2018
Medical artificial intelligence (AI) company Bay Labs and Northwestern Medicine announced that the first patient has...
QView Medical Showcases QVCAD for ABUS Exams at RSNA 2018
News | Ultrasound Women's Health | November 19, 2018
QView Medical will showcase QVCAD, the first U.S. Food and Drug Administration (FDA)-approved artificial intelligence (...
Immune Inflammatory Levels Linked to Disease-Free Survival in Prostate Cancer
News | Prostate Cancer | November 19, 2018
Data from a validation study of a high-risk prostate cancer trial suggests that higher levels of pretreatment...
Lunit Unveiling AI-Based Mammography Solution at RSNA 2018
News | Mammography | November 15, 2018
Medical artificial intelligence (AI) software company Lunit will be returning to the 104th Radiological Society of...
Breast Density Advocate Nancy M. Cappello Passes Away

Nancy Cappello. Image courtesy of AreYouDense.org.

News | Breast Density | November 15, 2018 | Jeff Zagoudis, Associate Editor
Imaging Technology News extends its condolences to the family, friends and colleagues of Nancy M. Cappello, Ph.D., who...
Life Image and Mendel.ai Bringing Artificial Intelligence to Clinical Trial Development
News | Artificial Intelligence | November 15, 2018
Life Image and Mendel.ai announced a new strategic partnership that will facilitate the adoption and enhancement of...
Artificial Intelligence Predicts Alzheimer's Years Before Diagnosis
News | Neuro Imaging | November 14, 2018
Artificial intelligence (AI) technology improves the ability of brain imaging to predict Alzheimer’s disease, according...
Merit Medical Completes Acquisition of Cianna Medical
News | Women's Health | November 14, 2018
Disposable device manufacturer Merit Medical Systems Inc. announced the closing of a definitive merger agreement to...
The MOZART Supra Specimen Tomosynthesis System is the latest generation of 3-D imaging for breast cancer surgery.
News | Breast Imaging | November 08, 2018
KUBTEC announced the launch of a new innovation in the treatment of breast cancer. The Mozart Supra Specimen...