News | May 14, 2014

CT-guided Irreversible Electroporation Safe in Unresectable Pancreatic Carcinoma

May 14, 2014 — A small group of patients with locally advanced unresectable pancreatic carcinoma suffered no major ill effects — pancreatitis or fistula formation — after undergoing percutaneous computed tomography (CT)-guided irreversible electroporation (IRE) (a nonthermal ablation technology that is safe near vascular and ductal structures) as a therapy.

"Our findings exceeded our expectations," said Dr. Maria Paola Belfiore, a researcher at the Institute of Radiology, Second University of Naples. "In fact, three patients were down-staged, and so had a greater life expectancy. This is a great new promise for inoperable pancreatic tumors."

The ablation procedure was successful in 100 percent of the patients. These early results represent a good alternative to intraoperative IRE ablation, and offer a safe and feasible primary local treatment for locally advanced pancreatic cancer.

Belfiore presented the study at the 2014 annual meeting of the American Roentgen Ray Society (ARRS) in San Diego.

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