News | December 27, 2007

Cone-Beam CT Faster, Could Replace Conventional Mammography

December 29, 2007 - Cone-beam breast CT provides exceptional tissue contrast and can potentially reduce examination time with comparable radiation dose to conventional 2D mammography, according to a new study by a team of researchers from the University of Texas MD Anderson Cancer Center in Houston.

Cone-beam breast CT employs a large area X-ray beam in conjunction with a flat panel X-ray detector to scan and generate 3D images of the breast. The scanner is placed below a table on which the patient lies prone with the breast protruding through an opening. Only the breast is exposed to radiation resulting in improved image quality and sparing the rest of the patient's body from unnecessary radiation exposure. The scan can be completed in less than one minute with a single complete rotation of the x-ray tube-detector gantry around the breast. Unlike conventional CT, the patient is not moved through the gantry during scanning.

For the study, the researchers used cone-beam CT on 12 mastectomy specimens. The researchers discovered that structured noise on cone-beam CT was minimal because of the absence of overlapping tissue; that breast anatomy was well resolved on all images as skin, adipose, and glandular regions; and that microcalcifications within cancers were clearly shown. In addition, they discovered that the detection of cancers based on morphologic assessment of tissue structures could potentially be improved compared with mammography because of the lack of overlapping glandular tissue.

Conventional 2D mammography is currently the most prevalent imaging technique for screening and diagnosis of breast cancers. However, the 2D projection images can overlap normal tissue, soft tissue masses, and calcifications and affect the detection and visualization of cancer.

"Despite the advantage of excellent spatial resolution, conventional mammography is unable to diagnose all cancers, especially early cancers in dense breasts, and cancers in high risk women such as genetic carriers," said Wei Tse Yang, MD, lead author of the study.

The researchers believe that cone-beam CT may potentially be used to replace mammography in screening and diagnostic breast imaging.

"In addition to overcoming the problem of overlapping breast tissue, cone-beam breast CT has the ability to provide true 3D images of the breast that may help depict the 3D morphology and distribution of lesions, and that may provide incremental benefit in the differentiation of abnormalities from background breast tissue. In addition, the multiplanar high-resolution surveys it provides are at a radiation dose comparable to routine mammography," said Dr. Yang.

Besides those benefits of cone-beam breast CT, the researchers pointed out others, as well.

"Scanning using this method takes less than one minute. This compares with 40 minutes for breast MRI, and 10 minutes for mammography. It also eliminates the discomfort associated with compression during mammography and the problem of claustrophobia during MRI," said Dr. Yang.

Source: The full results of this study appear in the December issue of the American Journal of Roentgenology, published by the American Roentgen Ray Society.

For more information: www.arrs.org

Related Content

Siemens Healthineers, Florida Hospital Collaborate to Improve Health Care Outcomes
News | CT Angiography (CTA) | January 23, 2018
January 23, 2018 – Siemens Healthineers and Florida Hospital, part of Adventist Health System, have announced a multi
Hospital for Special Surgery Invests in Sectra Orthopedic 3-D Planning Software
News | Orthopedic Imaging | January 18, 2018
January 18, 2018 – International medical imaging IT and cybersecurity company Sectra announces that Hospital for Spec
Philips Introduces Technology Maximizer Program for Imaging Equipment Upgrades
Technology | Imaging | January 17, 2018
January 17, 2018 — Philips recently announced the launch of Technology Maximizer, a cross-modality program designed t
Fat Distribution in Women and Men Provides Clues to Heart Attack Risk
News | Women's Health | January 11, 2018
January 11, 2018 – It’s not the amount of fat in your body but where it is stored that may increase your risk for hea
Minimally Invasive Treatment Provides Relief from Back Pain

Lumbar spine MRI showing disc herniation and nerve root at baseline and one month after treatment

News | Interventional Radiology | January 11, 2018
The majority of patients were pain free after receiving a new image-guided pulsed radiofrequency treatment for low back...
Emergency Radiologists See Inner Toll of Opioid Use Disorders

Rates of Imaging Positivity for IV-SUDs Complications. Image courtesy of Efren J. Flores, M.D.

News | Clinical Study | January 11, 2018
January 11, 2018 – Emergency radiologists are seeing a high prevalence of patients with complications related to opio
CT Shows Enlarged Aortas in Former Pro Football Players

3-D rendering from a cardiac CT dataset demonstrating mild dilation of the ascending aorta.

News | Computed Tomography (CT) | January 11, 2018
Former National Football League (NFL) players are more likely to have enlarged aortas, a condition that may put them at...

Size comparison between 3-D printed prosthesis implant and a penny.

News | 3-D Printing | January 11, 2018
January 11, 2018 — Researchers using...
BlueCross BlueShield Companies in Eight States Issue Positive Medical Policies for HeartFlow FFRct Analysis
News | CT Angiography (CTA) | December 28, 2017
HeartFlow Inc. announced that Health Care Service Corp. (HCSC), which operates Blue Cross and Blue Shield plans in five...
Artificial intelligence was the number one topic in radiology in 2017.

Artificial intelligence was the number one topic of interest in radiology in 2017, based on the most popular articles and videos on ITN in 2017.

Feature | Imaging | December 28, 2017
The Imaging Technology News (ITN) website had another record year with more than 1.25 million page views in 2017.
Overlay Init