News | August 18, 2014

Clinical Study Uses Hyperthermia, Proton Therapy to Treat Patients With Soft Tissue Sarcoma

August 18, 2014 — BSD Medical Corp. reported initiation of a Phase I/II study (HYPROSAR) using hyperthermia, delivered using either the BSD-2000 Hyperthermia System (BSD-2000) or the BSD-500 Hyperthermia System (BSD-500), combined with proton radiotherapy to treat patients with unresectable soft tissue sarcoma. The clinical study has been designed in joint cooperation with Kantonsspital Aarau, Paul Scherrer Institute, Villigen, Uniklinik Balgrist, Zurich, and University Hospital, Zurich. The Phase I/II study will include 28 adult patients with primary and unresectable soft tissue sarcomas of extremities and trunk (excluding abdominal tumors). The trial has been registered at ClinicalTrials.gov (NCT01904565) and is open for patient enrollment.

The researchers announced the study initiation at the European Society for Hyperthermic Oncology (ESHO) Annual Conference. Dr. N.R. Datta presented the basis for the study, "Thermoradiobiological basis of ''HYPROSAR'': A clinical trial with hyperthermia and proton radiotherapy in unresectable soft tissue sarcoma." During the presentation, Datta stated that studies have demonstrated that hyperthermia increases the efficacy of radiation with minimal morbidity, is especially cytotoxic for large bulky tumors, and prevents the repair of radiation induced DNA damage. He also reported that proton beam radiotherapy has superior physical dose distribution profiles, as compared to conventional radiotherapy. Datta concluded, "Consequently, for unresectable primary and recurrent soft tissue sarcomas, the thermoradiobiological and physical advantages of hyperthermia and proton beam radiotherapy could be expected to produce a greater tumour regression, higher tumour downstaging, superior resectability with organ and limb preservation and improved survival outcome without significant treatment related morbidity."

For more information: www.BSDMedical.com

Related Content

Mevion Receives 510(k) Clearance for Hyperscan Pencil Beam Scanning Proton Therapy
Technology | Proton Therapy | January 04, 2018
Mevion Medical Systems has received U.S. Food and Drug Administration (FDA) 510(k) clearance for the Mevion S250i...
MEDraysintell Downgrades Proton Therapy Market Projection for 2030
News | Proton Therapy | January 02, 2018
MEDraysintell recently downgraded its projection for proton therapy rooms expected to be operational in 2030 from 1,200...
RaySearch Releases RayStation 7 Radiotherapy Treatment Planning System
Technology | Treatment Planning | December 19, 2017
RayStation 7, the latest release of RaySearch’s radiation therapy treatment planning system, adds new functionality and...
Baptist Hospital's Miami Cancer Institute Treats First Patient With Proteus Plus Proton Therapy
News | Proton Therapy | December 19, 2017
December 19, 2017 — IBA (Ion Beam Applications SA) announced that Miami Cancer Institute treated its first patients,
Mevion Achieves CE Mark for S250i Proton Therapy System
News | Proton Therapy | November 21, 2017
November 21, 2017 — Mevion Medical Systems announced the Mevion S250i...
RayStation Selected for New Tennessee Proton Therapy Center
News | Treatment Planning | November 20, 2017
November 20, 2017 — Provision Healthcare has selected RayStation for external beam planning at the new Provision Care
Proton therapy doesn’t get as near to the heart and other internal organs as X-ray therapy does. (Image courtesy of Provision Cares Proton Therapy Center.)

Proton therapy doesn’t get as near to the heart and other internal organs as X-ray therapy does. (Image courtesy of Provision Cares Proton Therapy Center.)

Feature | Proton Therapy | November 06, 2017 | By Larisa Brass, MPH
Thirty-three. Twenty-nine. Sixty-four. These are the ages of the breast cancer patients who have walked through the...
PTCOG-NA Studies Address Cost and Coverage Issues With Proton Therapy
News | Proton Therapy | November 01, 2017
Physicians from across the country gathered in Chicago last week to discuss the most recent advances in proton therapy...
Proton Therapy Lowers Treatment Side Effects in Pediatric Head and Neck Cancer Patients
News | Proton Therapy | November 01, 2017
Pediatric patients with head and neck cancer can be treated with proton beam therapy (PBT) instead of traditional...
Proton Therapy Shows Promising Clinical Benefits for Esophageal, Prostate and Breast Cancer
News | Proton Therapy | October 30, 2017
The National Association for Proton Therapy (NAPT) announced a number of clinical papers showing promising results were...
Overlay Init