June 16, 2008 - Cardinal Health will open three additional Positron Emission Tomography (PET) radiopharmaceutical manufacturing facilities near its existing nuclear pharmacy locations this year, the company said today at SNM 2008.

These manufacturing facilities use cyclotrons to produce fluorine-18 (F-18), the radioactive precursor needed to create fluorodeoxyglucose (FDG), the PET imaging agent commonly used to diagnose various diseases. FDG’s relatively short half-life of just under two hours makes it challenging to efficiently distribute the product over great distances.

By locating cyclotrons near its nuclear pharmacy sites, Cardinal Health is able to efficiently distribute FDG to a greater number of hospitals, clinics and research facilities using its comprehensive fleet and logistics capabilities.

The company currently operates 22 cyclotrons and distributes PET products through nearly half of its more than 150 U.S. nuclear pharmacy locations. This year Cardinal Health will open three new cyclotrons located in Tampa, FL,, Hartford, CN,. and Louisville, KY.

In addition to FDG, the company’s new cyclotrons will produce a variety of other PET imaging agents to support oncology, neurology and cardiac imaging procedures.

The company’s new cyclotron facility in Tampa will be its third in the state, supplementing existing radiopharmaceutical manufacturing sites in Ft. Lauderdale and Orlando. It will be located on the campus of the H. Lee Moffitt Cancer & Research Center, where it will support research and clinical programs in oncology. It will also supply imaging agents to other customers in the greater Tampa area.

The company’s new facility in Hartford will house the first commercial cyclotron in the state; and its Louisville cyclotron will be the company’s first in Kentucky. The Hartford site will enhance Cardinal Health’s ability to serve nuclear pharmacy customers in New England, an area that is also serviced from its Boston and East Rutherford, NJ, sites. The Louisville cyclotron will join Cardinal Health’s Cincinnati manufacturing facility in servicing central and northern Kentucky. It will also join the company’s St. Louis site in servicing western Kentucky.

For more information: www.cardinalhealth.com


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