Conventional 3D T1W image (A) without segmentation, (B) with segmentation by Neuroquant, and (C) with segmentation by Freesurfer; ultrafast 3D-EPI T1W image (D) without segmentation, (E) with segmentation by Neuroquant, and (F) with segmentation by Freesurfer. Pallidum (asterisks) appears larger for Freesurfer (C, F) than for NeuroQuant (B, E), but appears similar in size between two sequences for each software package. For both software packages, bilateral frontal and occipital cortices (B, C) at bone-tiss

Conventional 3D T1W image (A) without segmentation, (B) with segmentation by Neuroquant, and (C) with segmentation by Freesurfer; ultrafast 3D-EPI T1W image (D) without segmentation, (E) with segmentation by Neuroquant, and (F) with segmentation by Freesurfer. Pallidum (asterisks) appears larger for Freesurfer (C, F) than for NeuroQuant (B, E), but appears similar in size between two sequences for each software package. For both software packages, bilateral frontal and occipital cortices (B, C) at bone-tissue interface appear more color-coded for conventional than for ultrafast sequence, contributing to larger cortical gray matter for conventional sequence


January 5, 2022 — According to an article in ARRS’ American Journal of Roentgenology (AJR), brain volume measurements in memory-impaired patients show significant differences and systematic biases between conventional and ultrafast 3D T1-weighted (T1W) MRI sequences.

“In patients for whom severe motion artifact precludes use of the conventional sequence, the ultrafast sequence may be useful to enable brain volumetry,” wrote corresponding author Hye Jin Baek of Gyeongsang National University and Changwon Hospital in Korea. “However, the current conventional 3D T1W sequence remains preferred in patients who can tolerate the standard examination.”

To compare automated brain volume measurements between conventional 3D T1W and ultrafast 3D echo-planar imaging (EPI) T1W sequences, Baek and colleagues retrospectively studied 36 patients (25 women, 11 men; mean age, 68 years) with memory impairment who underwent 3-T brain MRI. Examinations included both isotropic 3D T1W using inversion recovery gradient-recalled echo sequence (slice, 1.0 mm; acquisition, 3:04) and, in patients exhibiting motion, isotropic 3D EPI T1W sequence (slice, 1.2 mm; acquisition, 0:30). Using NeuroQuant (CorTechs Labs) and FreeSurfer (Harvard University) software to automate brain segmentation, measurements were compared between sequences for nine regions in each hemisphere.

For automated brain volumetry from ultrafast 3D EPI T1W imaging, compared with conventional 3D T1W imaging, most regions demonstrated at least substantial agreement between the two sequences—yet also significantly different mean values, moderate or large effect sizes, and consistent systematic biases with wide limits of agreement.

“The variation between the two sequences was observed in subset analyses of 16 patients with, and 20 patients without, Alzheimer disease,” the authors of this AJR article added.

For more information: www.arrs.org

Related Content

News | Digital Radiography (DR)

January 25, 2022 — Carestream Health was awarded 45 new patents in 2021 for global advances in artificial intelligence ...

Time January 26, 2022
arrow
News | Radiology Education

January 25, 2022 — Technical Prospects, a leader in the medical imaging industry, has announced the launch of its BioMed ...

Time January 25, 2022
arrow
News | Lung Imaging

January 25, 2022 — A new study based on data from a national cancer registry in Taiwan found evidence that lung cancer ...

Time January 25, 2022
arrow
Sponsored Content | Videos | Magnetic Resonance Imaging (MRI)

With the recent launch of the Magnifico Open, Italian company Esaote has entered the open MRI whole body space. ITN had ...

Time January 24, 2022
arrow
News | Ultrasound Imaging

January 21, 2022 — According to an article in ARRS’ American Journal of Roentgenology (AJR), preoperative shear wave ...

Time January 21, 2022
arrow
Sponsored Content | Case Study | Computed Tomography (CT)

Approximately thirteen men out of every 100 will get prostate cancer during their lifetime, and about two to three men ...

Time January 21, 2022
arrow
Feature | Radiology Business | By Jef Williams

The Great Resignation has impacted every industry, including ours. While this movement will be studied for years to come ...

Time January 20, 2022
arrow
Feature | Contrast Media Injectors | By Melinda Taschetta-Millane

Contrast media injectors are used to inject contrast agents to enhance the blood and perfusion in tissues. There have ...

Time January 19, 2022
arrow
Feature | Coronavirus (COVID-19) | By Avielle Siegel, Paul J. Chang, David M. Paushter, et al.

A 26-year-old man with history of diabetes and hypertension presented with 7 days of fever, chills, nausea, intractable ...

Time January 19, 2022
arrow
Sponsored Content | Case Study | Ultrasound Imaging

The most common cause of chronic liver disease? Nonalcoholic fatty liver disease (NAFLD). With 25% of the world’s ...

Time January 19, 2022
arrow
Subscribe Now