News | Radiopharmaceuticals and Tracers | June 05, 2019

BGN Technologies Introduces Novel Medical Imaging Radioisotope Production Method

Novel technique enables simultaneous production of molybdenum-99 and other isotopes without the need for highly enriched, weapons-grade uranium

BGN Technologies Introduces Novel Medical Imaging Radioisotope Production Method

June 5, 2019 – BGN Technologies, the technology transfer company of Ben-Gurion University (BGU), introduced a novel method for producing radioisotopes for nuclear medicine and medical imaging technologies such as computed tomography (CT) scan and positron emission tomography-computed tomography (PET-CT).

Developed by Alexander Tsechanski, Ph.D., from the BGU Department of Nuclear Engineering, the new technique obviates the need for highly enriched, weapons-grade uranium and a nuclear reactor. Nuclear medicine often necessitates the use of technetium-99m (Tc-99m) as the isotope for imaging, an unstable technetium isotope with a only a six-hour half-life that requires onsite production. In order to produce it in an economically efficient way, currently it requires weapons-grade, highly enriched uranium and a nuclear reactor to generate molybdenum-99 (Mo-99), which decays into technetium-99m (Tc-99m).

The new invention uses the naturally occurring and stable molybdenum-100 (Mo-100) isotope and a linear electron accelerator to generate Mo-99 and Tc-99m1. This process can also simultaneously generate other short-lived radioisotopes such as F-18, O-15, N-13 and C-11 as byproducts for use in PET scans.

BGN Technologies said it is currently looking for partners for further developing and commercializing the technology.

For more information: www.in.bgu.ac.il

Related Radiopharmaceuticals Content

Shine Medical Technologies Breaks Ground on U.S. Medical Isotope Production Facility

University of Missouri Research Reactor Files to Start U.S. Production of Medical Isotopes

FDA Clears Path for First Domestic Supply of Tc-99m Isotope

Reference

1. Fedorchenkoa D.V. and Tsechanski A. Photoneutronic aspects of the molybdenum-99 production by means of electron linear accelerators. Nuclear Inst. and Methods in Physics Research B, published online Oct. 23, 2018. https://doi.org/10.1016/j.nimb.2018.10.018

Related Content

An illustration based on simulations by Rice University engineers shows a gadolinium ion (blue) in water (red and white), with inner-sphere water -- the water most affected by the gadolinium -- highlighted. The researchers’ models of gadolinium in water show there’s room for improvement in compounds used as contrast agents in clinical magnetic resonance imaging.

An illustration based on simulations by Rice University engineers shows a gadolinium ion (blue) in water (red and white), with inner-sphere water -- the water most affected by the gadolinium -- highlighted. The researchers’ models of gadolinium in water show there’s room for improvement in compounds used as contrast agents in clinical magnetic resonance imaging. Illustration by Arjun Valiya Parambathu

News | Magnetic Resonance Imaging (MRI) | September 20, 2021
September 20, 2021 — ...
IBA (Ion Beam Applications S.A., EURONEXT), a world leader in particle accelerator technology, and SCK CEN (Belgian Nuclear Research Center) announced a strategic R&D partnership to enable the production of Actinimum-225 (225Ac), a novel radioisotope which has significant potential in the treatment of cancer.
News | Radiation Oncology | September 17, 2021
September 17, 2021 — IBA (Ion Beam Applications S.A., EURONEXT), a world leader in particle accelerator technology, a
Strategies to help guide nuclear radiology teams at various healthcare systems in 2021 and beyond
Feature | Nuclear Imaging | September 16, 2021 | By Staff of the American Society of Nuclear Cardiology (ASNC)
A year after COVID-19 turned the world upside do
Evaluation of therapeutic efficacy of drug candidates in preclinical oncology with positron emission tomography (PET)

Getty Images

Feature | PET Imaging | September 14, 2021 | By Todd Sasser, Ph.D.
Plan to attend RSNA21 at McCormick Place Chicago, Nov. 28 – Dec. 2, 2021

Getty Images

News | RSNA | September 13, 2021
September 13, 2021 — The Radiological Society of North America (RSNA) today announced highlights of the Technical Exh

Image of a STING protein, courtesy of UCLA Jonsson Comprehensive Cancer Center

News | PET Imaging | September 08, 2021
September 8, 2021 — A new study from scientists at the UCLA Jonsso...
Gallium-68 from GalliaPharm is used for the preparation of diagnostic imaging drugs in Positron Emission Tomography (PET).
News | PET Imaging | September 03, 2021
September 3, 2021 — Eckert & Ziegler Radiopharma GmbH has successfully submitted an amendment to their Drug Maste