News | Medical 3-D Printing | June 13, 2016

3-D Printed Aortic Valve Helps Treat Heart Condition

Researchers use model of aortic valve to assess blood flow of patient with severe vessel narrowing

3-D printing, aortic valve model, aortic stenosis, Cleveland Clinic, ASE 2016

Image courtesy of Henry Ford Hospital.

June 13, 2016 – While 3-D printing has been around since the mid-1980s, there is accumulating evidence that this technology has the potential to revolutionize the understanding and management of heart conditions. A team of researchers from the Cleveland Clinic created a 3-D model of an aortic valve from a patient with a severe case of calcific aortic stenosis (AS) — narrowing of the aortic valve — to simulate the patient’s beating heart and assess the blood flow, or “hemodynamics.”   

“In order to better understand the physiology of AS (which can be complex), we produced a true replicate of the valve using 3-D printing technology. Then, to assess the valve hemodynamics, we placed the 3-D-printed valve into a circuit where flow can be controlled and we can try out different flow conditions. In this research, we present a proof of concept case of severe AS where the pressure gradients, obtained by cardiac ultrasound, were successfully replicated in the circuit built around the 3-D-printed version of the stenotic valve,” said lead author Serge Harb, M.D., of Cleveland Clinic, Cleveland, Ohio. 

The hemodynamic results using this 3-D-printed valve in the flow circuit simulating the pumping action of the heart, were confirmed by Doppler echocardiography, the technique used in daily practice to evaluate patients with AS. Harb said, “This technology shows a lot of promise. Not only will it help us better understand the mechanisms of the disease, but it also has the potential to provide a more personalized treatment where the particular valve of the affected patient is 3-D-printed, guiding its optimal management. This may be particularly helpful for surgical planning, or when using new catheter-based technologies for non-surgical valve replacement.” 

Researchers on the study, Three Dimensional (3D) Printing and Functional Assessment of Aortic Stenosis Using a Flow Circuit: Feasibility and Reproducibility, include Harb, Ryan Klatte, Brian P. Griffin and Leonardo L. Rodriguez, from the Cleveland Clinic Foundation, Cleveland, Ohio.

Harb presented a poster based on this research during the American Society of Echocardiography (ASE) 27th Annual Scientific Sessions, June 10-14 in Seattle.

For more information: www.asescientificsessions.org

Related Content

Siemens Partnership will make better health easier throughout Pennsylvania and in all communities that Geisinger serves

Getty Images

News | Radiology Business | June 08, 2020
June 8, 2020 — Siemens Healthineers and Geisinger have estab
Figure 4 for the study. Images of a 65-year-old man (patient 6). (a) Cardiac MRI perfusion shows perfusion deficit of anterior/anterolateral wall attributed to left anterior descending artery/left circumflex artery (*). (b) CT coronary angiography. (c) Coronary angiography, left anterior oblique projection with caudal angulation. (d) Three-dimensional image fusion helped refine diagnosis: perfusion deficits (*) were most likely caused by narrow first diagonal branch and its first, stented side branch.

Figure 4 for the study. Images of a 65-year-old man (patient 6). (a) Cardiac MRI perfusion shows perfusion deficit of anterior/anterolateral wall attributed to left anterior descending artery/left circumflex artery (*). (b) CT coronary angiography. (c) Coronary angiography, left anterior oblique projection with caudal angulation. (d) Three-dimensional image fusion helped refine diagnosis: perfusion deficits (*) were most likely caused by narrow first diagonal branch and its first, stented side branch (arrowhead). Retrospectively, denoted lesion could also be found at CT coronary angiography and coronary angiography (arrowheads in b and c, respectively). CT FFR = CT-derived fractional flow reserve, LGE = late gadolinium enhancement. Image courtesy of RSNA, Radiology.

News | Cardiac Imaging | May 04, 2020
May 4, 2020 – A new technique that combines computed tomography (CT) and magnetic resonance imaging MRI can bolster c
360 Photos | 360 View Photos | April 30, 2020
The company .decimal at ASTRO showed a 3-D prin
Two examples of CT myocardial perfusion (CTP) imaging assessment software. Canon is on the left and GE Healthcare is on the right. Both of these technologies have been around for a few years, but there have been an increasing amount of clinical data from studies showing the accuracy of the technology compared to nuclear imaging, the current stand of care for myocardial perfusion imaging, and cardiac MRI. #SCCT #perfusionimaging 

Two examples of CT myocardial perfusion (CTP) imaging assessment software. Canon is on the left and GE Healthcare is on the right. Both of these technologies have been around for a few years, but there have been an increasing amount of clinical data from studies showing the accuracy of the technology compared to nuclear imaging, the current stand of care for myocardial perfusion imaging, and cardiac MRI.

News | Computed Tomography (CT) | March 16, 2020
March 16, 2020 — The Society of Cardiovascular Computed Tomography (SCCT) released a new...
Carestream’s X-ray digital tomosynthesis functionality creates three-dimensional datasets from digital radiography (DR) that can be scrolled through similar to computed tomography (CT) imaging. It received 510(k) clearance from the U.S. Food and Drug Administration (FDA) in January 2020. Digital tomosynthesis uses a single sweep of X-ray exposures and streamlines operator workflow by separating the process of DT exposure acquisition from image volume formation.
News | Digital Radiography (DR) | January 15, 2020
January 15, 2020 — Carestream’s X-ray digital tomosynthesis (DT) functionality, which creates three-dimensional datas
Videos | RSNA | January 13, 2020
ITN Editor Dave Fornell takes a tour of some of the most innovative new medical imaging technologies displayed on the
Videos | Advanced Visualization | December 30, 2019
This is a hologram of a fracture from a...
Videos | RSNA | December 18, 2019
ITN Editor Dave Fornell and ITN Consulting Editor Greg Freiherr offer a post-game report on the trends and technologi