News | Molecular Imaging | July 08, 2015

Traumatic Brain Injury Can Now Be Identified With SPECT

Large neuroimaging study finds nuclear imaging method can distinguish TBI from post-traumatic stress disorder

SPECT, traumatic brain injury, TBI, post-traumatic stress disorder, PTSD

July 8, 2015 - After comparing more than 20,000 brain scans, researchers have identified differences between traumatic brain injury (TBI) and post-traumatic stress disorder (PTSD) despite both conditions sharing common symptoms.

"This discovery is breakthrough information for anyone diagnosed with either TBI or PTSD or both," said Theodore Henderson, M.D., Ph.D., a co-author of the study, published in PLOS One. "Now that we can tell the difference between TBI and PTSD, clinicians can apply more targeted and appropriate treatments, and achieve advances with their patients."

Believed to be the largest functional neuroimaging study ("Functional Neuroimaging Distinguishes Post traumatic Stress Disorder from Traumatic Brain Injury in Focused and Large Community Datasets"), researchers used single photon emission computed tomography (SPECT) to obtain biological differences between TBI and PTSD in the brain. This neuroimaging method and landmark study "demystify" these two conditions that both may appear with symptoms like anxiety, depression, mood dysregulation, irritability and other cognitive breakdowns, according to Henderson.

"This study contained a subset of closely matched patients and a larger dataset of "˜real world' patients with multiple psychiatric or neurological conditions. The accuracy of the closely matched study was 100 percent, which replicates our research on veterans with TBI or PTSD (wherein the accuracy was 94 percent). It clearly delineates the potential of SPECT as a biomarker in differentiating TBI from PTSD - a critical issue for anyone suffering from symptoms with no answers," said Henderson, a Denver-based psychiatrist specializing in treating complex conditions.

Henderson emphasized the importance of obtaining an accurate diagnoses for TBI or PTSD. "They may have similar symptoms, but treatments are very different," he said.

"For example, some treatments for PTSD can actually be useless and possibly even harmful for TBI," said Henderson. "Plus, TBI can refer to injury to any part of the brain, which would require different treatments as well."

Henderson said this news will be particularly noteworthy for the millions of Americans who have played contact sports, citing sport-related concussion incidence rates being reported to top 3 million per year, according to the Center for Disease Control. "I hope to reach out to all the active and retired football players and athletes suffering from either of these conditions."

For more information: www.plosone.org

Related Content

Chest X-ray AI Algorithm Correctly Identifies Lung Disease for Dubai Health Authority
Feature | Artificial Intelligence | April 17, 2018
The Dubai Health Authority (DHA) announced the preliminary results of a chest X-ray artificial intelligence (AI)...
Novel PET Agent Could Help Guide Therapy for Brain Diseases

Rat brain 11C‐Me‐NB1 PET images (0‐60 min) superimposed on an MRI template. Credit: SD Krämer et al., ETH Zurich, Zurich, Switzerland

News | PET Imaging | April 10, 2018
Researchers have developed a new imaging agent that could help guide and assess treatments for people with various...
First Patient Treated in Online Adaptive Radiotherapy Trial With CyberKnife System
News | Stereotactic Body Radiation Therapy (SBRT) | April 06, 2018
Accuray Inc. and Erasmus MC announced the first patient has been successfully treated using an online-adaptive (OA)...
News | Endoscopes | April 02, 2018
Results from a recent prospective trial found the Wide Area Transepithelial Sampling with 3D Tissue Analysis (WATS3D)...
The Chalk River nuclear reactor license has been renewed, but will be decommissioned by 2028.

The Chalk River nuclear isotope reactor license has been renewed, but will be decommissioned by 2028. The reactor supplies about 50 percent of the world's supply of Tc99m.

Feature | Nuclear Imaging | April 02, 2018 | Dave Fornell
April 2, 2018 – The Canadian Nuclear Safety Commission (CNSC) announced March 29 that it renewed Canadian Nuclear Lab
Edwards Completes Enrollment in PARTNER 3 Low-Risk CT Sub-Study
News | Computed Tomography (CT) | March 27, 2018
March 27, 2018 — Edwards Lifesciences Corp.
Combination Radiotherapy Beneficial in Treating Prostate Cancer
News | Prostate Cancer | March 27, 2018
March 27, 2018 — While there are many treatment options for men with...
3-D Printed Models Improve Medical Student Training
News | Medical 3-D Printing | March 23, 2018
March 23, 2018 — A relatively inexpensive...
Overlay Init