News | December 17, 2006

Study: GeneSearch Detects Metastases with Greater Sensitivity

A prospective clinical study shows that the GeneSearch Breast Lymph Node Assay, a gene-based diagnostic test, has greater sensitivity than traditional intra-operative methods of detecting the spread of breast cancer to the lymph nodes. In the study, sponsored by Veridex LLC, the GeneSearch demonstrated overall sensitivity at least 10 percentage points higher than intra-operative tests.

In the study, which involved 416 evaluable patients across 11 clinical trial sites, sentinel lymph nodes were tested during surgery. In a head-to-head comparison with frozen section, overall sensitivity of GeneSearch was 95.6 percent — 10 points greater than the overall sensitivity of frozen section (85.6 percent). In a comparison with touch preparation, overall sensitivity of GeneSearch was 18 points higher.

Related Content

Breast Cancer Follow-up Imaging Varies Widely
News | Breast Imaging | July 13, 2018
July 13, 2018 — Follow-up imaging for women...
Invision Diagnostics Installs VolparaEnterprise Software to Enhance Mammography Image Quality
News | Mammography | July 11, 2018
Invision Diagnostics, a provider of mobile mammography services across North and South Carolina, announced that it is...
Breast Cancer Studies Ignore Race, Socioeconomic Factors
News | Women's Health | July 11, 2018
A new commentary appearing in the July issue of Cancer Causes & Control points to evidence that social factors help...
Jeffrey Hoffmeister, M.D.

Jeffrey Hoffmeister, M.D.

Feature | Breast Imaging | July 05, 2018 | By Jeffrey Hoffmeister, M.D.
When women reach age 40, an annual mammogram becomes a necessary part of their healthcare ritual — regardless if they...
Researcher Investigates Eliminating Radiation for HER2-Positive Breast Cancer
News | Radiation Therapy | July 02, 2018
Researchers at The University of Kansas Cancer Center have launched a clinical trial that eliminates radiation from the...
Norwegian Study Confirms Higher Cancer Rate in Women with Dense Breast Tissue
News | Breast Density | July 02, 2018
A large Norwegian study using automated breast density measurements found that women with mammographically dense breast...
3-D Imaging and Computer Modeling Capture Breast Duct Development

An image of a developing mammary duct. Image courtesy of Andrew Ewald.

News | Breast Imaging | June 28, 2018
A team of biologists has joined up with civil engineers to create what is believed to be the first 3-D computer model...
FDA Article Underscores Benefits of Adequate Breast Compression for Mammography Image Quality
News | Mammography | June 26, 2018
Inadequate breast commission played a role in up to 38 percent of mammogram image quality deficiencies, according to a...
Clinical Trial Testing Topical Gel to Reduce Breast Density
News | Breast Density | June 19, 2018
Women with dense breast tissue soon might be adding a new product to their skincare routine to help them fight breast...
California Women In Favor of Extending State's Breast Density Inform Law
News | Breast Density | June 15, 2018
A recent survey of California women found that 95 percent of respondents want the state’s breast density inform law to...
Overlay Init