News | January 22, 2014

Strut-based Breast Brachytherapy Association With Low Risk of Recurrence, Study Shows

Ability to customize radiation therapy improves patient safety and quality

Cianna Medical, Inc., a women’s health company, today announced the outcomes of a large, retrospective study demonstrating the safety and efficacy of the SAVI breast brachytherapy applicator. Researchers reported favorably low recurrence rates, high rates of survival and excellent cosmetic outcomes. SAVI is a strut-based applicator that delivers a form of accelerated partial breast irradiation (APBI) known as breast brachytherapy, a 5-day course of targeted radiation for early-stage breast cancer.

Data came from the SAVI Collaborative Research Group (SCRG), which studies the long-term outcomes of women treated with strut-based brachytherapy, and will be presented at the 36th annual San Antonio Breast Cancer Symposium, Dec. 10-14, 2013.

Researchers examined data from 576 patients with a median follow-up of more than 3 years. The two-year actuarial local recurrence rate was 1.17%, and overall survival over the same time period was 99.5%. During follow up, the rate of late toxicities was very low (< 5%), and 98.5% reported excellent or good cosmesis at 48 months.

“With recurrence rates comparable to whole breast irradiation, strut-based brachytherapy has proven to be an effective treatment for a certain population of early-stage breast cancer patients,” said lead author Catheryn Yashar, M.D., a radiation oncologist at UC San Diego’s Moores Cancer Center, La Jolla, Calif., and co-principal investigator of the SCRG. “In addition, the ability to precisely target radiation to the tumor bed makes it a very well-tolerated treatment with fewer late toxicities and side effects compared to other forms of radiation therapy.”

In contrast, two studies were published last month in The Lancet and The Lancet Oncology journals addressing another form of APBI known as intraoperative radiation therapy (IORT). Both randomized studies compared IORT to whole breast radiation, and researchers reported rates of local recurrence with IORT that were 11 and 2.5 times higher than with whole breast radiation.

Strut-based brachtherapy is used as part of breast conservation therapy (BCT), which consists of a lumpectomy followed by radiation therapy. Traditionally, the radiation portion consisted of whole breast irradiation (WBI), which requires 6-7 weeks of daily treatments. Breast brachytherapy delivers radiation to the area immediately surrounding the lumpectomy cavity, enabling treatment to be completed in as little as 5 days and sparing healthy tissue from unnecessary radiation. Patient eligibility for breast brachytherapy is based on a number of factors, including tumor size, age, margin status and lymph node involvement.

The strut-based, open architecture design of SAVI allows physicians to sculpt radiation based on patient-specific anatomy, which may increase the number of women eligible for breast brachytherapy.

For more information: www.ciannamedical.com

Related Content

Warm Springs Health & Wellness Center Implements Digisonics Solution for OB Ultrasound
News | Ultrasound Women's Health | June 17, 2019
Warm Springs Health & Wellness Center in Warm Springs, Ore., has selected the Digisonics OB PACS (picture archiving...
Fujifilm Announces Nationwide Breast Health Campaign With Mobile Mammography Coach

At the center of the campaign, Fujifilm will be traveling around the U.S. with its "Aspire to Be Fearless" mobile mammography coach to provide educational opportunities for clinicians, raise awareness about the importance of screening and will be providing mammograms to the underserved population in key locations.

News | Mammography | June 14, 2019
Fujifilm Medical Systems U.S.A. Inc. announced a nationwide awareness campaign titled ‘Aspire to Be Fearless’ focused...
Ikonopedia Showcases Risk Assessment and Resolution Manager Tools at SIIM and AHRA
News | Mammography Reporting Software | June 13, 2019
Ikonopedia will showcase its suite of structured breast reporting and Mammography Quality Standards Act (MQSA)...
Sponsored Content | Videos | Radiology Imaging | June 13, 2019
In an interview with itnTV, Henry Izawa, vice president, modality solutions and clinical affairs, Fujifilm Medical Sy
iCAD Introduces ProFound AI for 2D Mammography in Europe
News | Artificial Intelligence | June 13, 2019
iCAD Inc. announced the launch of ProFound AI for 2D Mammography in Europe. This software is the latest addition to...
Three Palm Software Releases WorkstationOne Version 1.8.8
Technology | Mammography Reporting Software | June 12, 2019
Three Palm Software announced the release of the 1.8.8 version of its breast imaging workstation, WorkstationOne. This...
Volpara Health Technologies to Acquire MRS Systems Inc.
News | Mammography Reporting Software | June 04, 2019
Volpara Health Technologies, Volpara Solutions' parent company, has signed a binding agreement to acquire U.S.-based...
62-year-old female patient presenting for 3D screening mammogram. Location of an indeterminate low-density circumscribed mass was not clearly determined as at the skin line or just under the surface.

62-year-old female patient presenting for 3D screening mammogram. Location of an indeterminate low-density circumscribed mass was not clearly determined as at the skin line or just under the surface.

Feature | Mammography | May 31, 2019 | By Olive Peart M.S., R.T.(R)(M)
In recent years there has been a lot of debate about the role of the...
Quantitative Transmission Ultrasound Featured at Acoustical Society of America

Fused QT Ultrasound 3-D quantitative transmission ultrasound and compounded reflection axial images showing high resolution image of internal organs, tissue, skin and hair of neo-natal piglet. Anatomy courtesy of C. Ruoff, DVM.

News | Ultrasound Imaging | May 29, 2019
May 29, 2019 — QT Ultrasound recently showcased its advanced...
VolparaDensity With Tyrer-Cuzick Model Improves Breast Cancer Risk Stratification
News | Breast Density | May 22, 2019
Research has demonstrated use of Volpara Solutions' VolparaDensity software in combination with the Tyrer-Cuzick Breast...