XKnife RT 4.0 is an update to XKnife RT 3.0 which is used by neurosurgeons, oncologists, physicists and dosimetrists. It will contain a number of new features that are intended to increase patient throughput and accelerate the planning process.
These new features include: sculpt mode contouring to create and edit contours by sculpting them from inside or outside the contour borders with a circular paint brush; bony segmentation to visualize bony anatomy without the need for contouring; split-slice contouring to visualize two correlated data sets simultaneously while contouring on either data set; IGRT isocenter translations that automatically determine the isocenter translation needed to correct for patient changes when using CBCT or other daily imaging tools; multiple isocenter translation to automatically restore the geometric relationship of each isocenter in the plan to the anatomy targeted during preplanning; surface dose colorwash to dynamically evaluate dose in a 3-D viewer using either red/blue thresholds, or colorwash rendering; synchronized viewers to zoom or set all viewers to a specified point simultaneously; DICOM-RT DRR Export; and universal QA Mode.
February 23, 2026 
