Technology | October 16, 2009

NeuroPak Deep Brain Imaging System Visualizes the Conscious Mind

VisualSonics Inc. introduced the NeuroPak Deep Brain Imaging System, a novel technology that provides pre-clinical neurology researchers with the capability to image biological and cellular processes in the brains of conscious animals.

It works with the Cellvizio LAB Imaging System, a miniature endoscopic fluorescence microscope, to allow users to repeatedly image a section of a small animal's brain, in real time while the animal is awake and moving freely.

While existing research tools limit access to near-surface imaging on sedated animals, Neuropak Imaging System allows researchers real time access to tissue, deep in the brain of a conscious animal, enabling researchers to determine how the brain reacts to different stimuli in real time.

The NeuroPak System uses a small implant in the skull of the mouse, placed over the area of interest in the brain, which allows repeated, reproducible insertion of the probe for imaging sessions which can be hours in duration. The CerboFlex Probe is a special fiber bundle probe designed to fit the implant that is very flexible and lightweight, thus the mouse is free to move around while the fiber probe is in place. The CellVizio LAB is capable of high resolution, real time imaging of fluorescent tissues, cells and markers at micron levels. Based on a robust, patented confocal technology which employs a high resolution fiber bundle, laser scanning unit and sensitive detector optics, the easy-to-use platform allows real-time imaging of microscopic biology inside a living animal.

"NeuroPak(TM) is the first commercially available means to simultaneously image and correlate cellular events in the intact central nervous system with the behavioral responses of laboratory mice," said David Bates, an Application Scientist at VisualSonics. "This imaging technology will enable groundbreaking research in a myriad of neurological disorders such as Alzheimer's, epilepsy and addiction."

The technique was developed as part of a research collaboration between scientists at Mauna Kea Technologies and the Institut Pasteur in Paris. VisualSonics is the exclusive global distributor for Mauna Kea Technologies pre-clinical imaging technologies, including the Cellvizio LAB In Vivo Fiberoptic Fluorescence Microscope, the NeuroPak Deep Brain Imaging System and the CerboFlex Deep Brain Imaging Probe.

For more information:

Related Content

Patient Complexity, Subspecialization Impact List Prices for Radiologists' Services
News | Business | August 15, 2017
A new study by the Harvey L. Neiman Health Policy Institute finds that patient condition complexity and...
Upcoming radiology conferences, meetings and events.
News | August 14, 2017
ITN maintains a comprehensive listing of radiology specialty meetings on its website at ...
ACR Establishes Education Committee for Patient- and Family-Centered Care
News | Patient Engagement | August 09, 2017
Members of the new Education Committee of the American College of Radiology (ACR) Commission on Patient- and Family-...
ACR Annual Conference on Quality and Safety Offers Strategies for Radiology Practices
News | Business | August 08, 2017
The American College of Radiology (ACR) Annual Conference on Quality and Safety, scheduled for Oct. 13-14 in Boston,...
Sponsored Content | Videos | Business | July 28, 2017
Angelic McDonald, MSRS, CRA, FAHRA, regional director of imaging, Baylor Scott & White Health and the president-e
Radiation dose tracking in medical imaging is helping increase patient safety by lower X-ray doses.
Feature | Radiation Dose Management | July 26, 2017 | Dave Fornell
Patient X-ray radiation exposure from medical imaging has been a hot topic in radiology the past few years and has pr
Radiologists Seek Greater Involvement in Patient Care
News | Patient Engagement | July 20, 2017
Despite time and workload constraints, radiologists are looking for ways to become more directly involved in the care...
ACR Updates Radiation Oncology and Medical Physics Guidance With ASTRO and AAPM
News | Radiation Dose Management | July 19, 2017
July 19, 2017 — The American College of Radiology (ACR) recently collaborated with professional medical societies to
SIIM Recognizes Innovators in Medical Imaging Informatics at 2017 Annual Meeting

Accepting the award on behalf of Arterys is Julia Geer shown with SIIM Chair Dr. Paul Nagy (left), and Innovation Challenge Co-Chair Dr. Ram Chadalavada (right)

News | Analytics Software | July 19, 2017
During the Society for Imaging Informatics in Medicine (SIIM) 2017 general closing session held in Pittsburgh, Fabien...
Overlay Init