News | July 31, 2013

MRI Detects Early Effects of Chemotherapy on Children's Hearts

July 31, 2013 — Magnetic resonance imaging (MRI) scans of children who have had chemotherapy can detect early changes in their hearts, according to research findings in BioMed Central's open access journal Journal of Cardiovascular Magnetic Resonance.

Chemotherapy with anthracyclines, such as Doxorubicin, is one of the most effective treatments against many types of cancer, including leukemia and Hodgkin's lymphoma, breast, lung and ovarian cancer. However it can also lead to irreversible heart damage, which may not be apparent until several years after treatment. Being able to detect this damage at an early stage, in order to initiate preventative therapy of affected people, is especially important in children.

Researchers from the University of Alberta performed MRI scans on children and young adults (aged 7 to 19) at the Stollery Children's Hospital who were in remission following anthracycline treatment. They found that they were able to identify changes in heart muscle related to the formation of fibrosis, using an emerging MRI method called T1 mapping, even in children whose heart function was apparently normal by ultrasound.

The study funded by the Women's and Children's Health Research Institute led by Edythe Tham, M.D., and Richard Thompson, M.D., said: "In childhood cancer survivors, MRI changes were related to anthracycline dose given to the children. These changes are also mirrored by thinning of the heart wall and a reduction in the exercise capacity. By detecting these changes early we can only hope that future research using these techniques may guide early identification and treatment in attempts to delay the onset of heart damage in children who have survived cancer."

For more information: www.biomedcentral.com

Related Content

Elekta Unity High-Field MR-Linac Receives CE Mark
News | Image Guided Radiation Therapy (IGRT) | June 18, 2018
Elekta announced that its Elekta Unity magnetic resonance radiation therapy (MR/RT) system has received CE mark,...
Washington University in St. Louis Begins Clinical Treatments With ViewRay MRIdian Linac
News | Image Guided Radiation Therapy (IGRT) | June 14, 2018
June 14, 2018 — The Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine in S
Reduced hippocampal volume on MRI

This figure shows reduced hippocampal volume over the course of 6 years as seen on progressive volumetric analysis and also coronal MRI evaluations (arrows).Progressive volume loss in the mesial temporal lobe on MRI is a characteristic imaging feature of AD. This patient was a case of Alzheimer’s Dementia.

 

News | Neuro Imaging | June 12, 2018
According to a UCLA Medical Center study, a new technology shows the potential to help doctors better determine when...
High Prevalence of Atherosclerosis Found in Lower Risk Patients
News | Magnetic Resonance Imaging (MRI) | June 08, 2018
Whole-body magnetic resonance angiography (MRA) found a surprisingly high prevalence of atherosclerosis in people...
Philips Receives FDA 510(k) for Ingenia Elition MR System
Technology | Magnetic Resonance Imaging (MRI) | June 07, 2018
Philips announced that it has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) for its...
New Studies Highlight MRI Use for Prostate Cancer Screening and Management
News | Magnetic Resonance Imaging (MRI) | May 21, 2018
Three new studies presented at the 113th annual meeting of the American Urological Association (AUA) highlight the...
MRI "Glove" Provides New Look at Hand Anatomy

An experiment showed that a glove-shaped detector could yield images of bones, cartilage, and muscles interacting as a hand 'plays piano.' Traditionally, MRI had required patients to remain strictly motionless.Image courtesy of Nature Biomedical Engineering; Bei Zhang, Martijn Cloos, Daniel Sodickson

News | Magnetic Resonance Imaging (MRI) | May 17, 2018
A new kind of magnetic resonance imaging (MRI) component in the shape of a glove delivers the first clear images of...
FDA Clears Medic Vision's iQMR MRI Image Enhancement Technology

Image courtesy of Medic Vision Imaging Solutions

Technology | Magnetic Resonance Imaging (MRI) | May 15, 2018
May 15, 2018 — Medic Vision Imaging Solutions Ltd. announced that the U.S.
Impaired Brain Pathways May Cause Attention Problems After Stroke
News | Neuro Imaging | May 10, 2018
Damage to some of the pathways that carry information throughout the brain may be responsible for attention deficit in...
Functional MRI Assesses Crocodile Brain Listening to Classical Music

A research team from Ruhr-Universität Bochum (RUB) used functional MRI to assess the brain patterns of a Nile crocodile and determine what happens when the animal hears complex sounds. Image courtesy of Felix Ströckens, M.D./Proceedings of the Royal Society B: Biological Sciences

News | Magnetic Resonance Imaging (MRI) | May 08, 2018
May 8, 2018 — In a first, an international research team from the Department of Biopsychology at Ruhr-Universität Boc
Overlay Init