News | Neuro Imaging | April 11, 2016

More than 40 Percent of Retired NFL Players Show Brain Injury

MRI study suggests positive relationship between number of years played in the NFL and likelihood of traumatic brain injury

retired NFL players, traumatic brain injury, MRI study, American Association of Neurology

April 11, 2016 — More than 40 percent of retired National Football League (NFL) players in a recent study had signs of traumatic brain injury based on sensitive magnetic resonance imaging (MRI) scans called diffusion tensor imaging, according to a new study. The study will be presented at the American Academy of Neurology’s 68th Annual Meeting in Vancouver, Canada, April 15-21, 2016.

“This is one of the largest studies to date in living retired NFL players and one of the first to demonstrate significant objective evidence for traumatic brain injury in these former players,” said study author Francis X. Conidi, M.D., DO, of the Florida Center for Headache and Sports Neurology and Florida State University College of Medicine in Tallahassee, Fla. Conidi is also a member of the American Academy of Neurology. “The rate of traumatic brain injury was significantly higher in the players than that found in the general population.”

For the study, researchers conducted thinking and memory tests in 40 retired NFL players, along with the brain scans. The players were an average age of 36, ranging from 27 to 56. A majority of the players had been out of the NFL for less than five years. They played an average of seven years in the NFL, with a range of two to 17 years. They reported an average of 8.1 concussions. Twelve players, or 31 percent, said they had several sub-concussive hits, or hits considered below the threshold of a diagnosed concussion.

The MRIs measured the amount of damage to the brain’s white matter, which connects different brain regions, based on the movement of water molecules in the brain tissue. Seventeen players, or 43 percent, had levels of movement 2.5 standard deviations below those of healthy people of the same age, which is considered evidence of traumatic brain injury with a less than 1 percent error rate.

Twelve of the former athletes, or 30 percent, showed evidence on traditional MRI of injury to the brain due to disruption of the nerve axons, those parts of nerve cells that allow brain cells to transmit messages to each other. On the tests of thinking skills, about 50 percent had significant problems on executive function, 45 percent on learning or memory, 42 percent on attention and concentration, and 24 percent on spatial and perceptual function.

The more years a player spent in the NFL, the more likely he was to have the signs of traumatic brain injury on the advanced MRI. However, there was no relationship between the number of concussions a player had and whether he had traumatic brain injury based on the advanced MRI. There was also no relationship between the number of years a player spent in the NFL and whether he had signs of brain damage on the traditional MRI.

“We found that longer careers placed the athletes at a higher risk of TBI,” said Conidi. “This research in living players sheds light on the possible pathological changes consistent with chronic traumatic encephalopathy that may be taking place.”

For more information: www.aan.com

Related Content

AAPM 2019 Features More Than 40 Presentations on ViewRay's MRIdian MRI-guided Radiotherapy
News | Image Guided Radiation Therapy (IGRT) | July 16, 2019
ViewRay Inc. announced that the company's MRIdian System is the focus of more than 40 abstracts selected by the...
FDA Approves Bayer's Gadavist Contrast for Cardiac MRI in Adult Coronary Artery Disease Patients
Technology | Contrast Media | July 15, 2019
The U.S. Food and Drug Administration (FDA) has approved Gadavist injection for use in cardiac magnetic resonance...
Insightec's Exablate Neuro Approved With GE Signa Premier MRI in U.S. and Europe
News | Focused Ultrasound Therapy | July 10, 2019
GE Healthcare and Insightec announced U.S. Food and Drug Administration (FDA) approval and CE mark for Insightec’s...
Delta T1 Maps Provide Quantitative, Automated Solution to Assess Brain Tumor Burden
News | Neuro Imaging | July 05, 2019
Imaging Biometrics LLC (IB) a subsidiary of IQ-AI Ltd., is highlighting a recently published study in the American...
Medic Vision Wins Japanese PMDA Clearance for iQMR Image Reconstruction Solution
News | Magnetic Resonance Imaging (MRI) | July 05, 2019
Medic Vision Imaging Solutions announced that its 3-D iterative image reconstruction technology for shortening magnetic...
Bay Labs Announces New Echocardiography Guidance Software Data at ASE 2019 Scientific Sessions
News | Cardiovascular Ultrasound | June 20, 2019
Bay Labs announced that new data on the company’s first-of-its-kind deep learning investigational guidance software...
Third FDA Clearance Announced for Zebra-Med's AI Solution for Brain Bleed Alerts
Technology | Artificial Intelligence | June 19, 2019
Zebra Medical Vision announced it has received its third U.S. Food and Drug Administration (FDA) 510(k) clearance for...
LVivo EF Comparable to MRI, Contrast Echo in Assessing Ejection Fraction
News | Cardiovascular Ultrasound | June 19, 2019
DiA Imaging Analysis announced the presentation of two studies assessing the performance and accuracy of the company's...
New Data Demonstrates Safety Profile of GammaTile Therapy for Various Brain Tumors
News | Brachytherapy Systems | June 18, 2019
GT Medical Technologies Inc. announced the presentation of clinical data from a prospective study of GammaTile Therapy...