Automatic detection and volumetric assessment of lymph nodes is a works-in-progress.

November 24, 2009 – Version 2.0 of a software application for the detailed analysis of lymph nodes allows the user to conduct side-by-side comparison and temporal tracking of images taken at different stages of lymph node development.

The original application is designed for radiologists to identify, analyze and evaluate lymph nodes in CT images. Once a radiologist has identified a lymph node, the application automatically segments the node and analyzes its properties. By quantifying lymph nodes according to RECIST and WHO guidelines and by volume, the application is designed to provide a more complete picture of lymph node size.

The upgrades in Definiens LymphExpert 2.0 include a browser-style interface that facilitates importation of data from imaging acquisition devices. Version 2.0 is also capable of maintaining large data sets that can be searched and ranked by demographics, case numbers and image features. In addition to improved analytics, version 2.0 incorporates a client architecture that gives radiologists remote access to their image data and analysis tools.

Definiens LymphExpert’s rapid analysis of CT images also assists pharmaceutical companies in evaluating candidate compounds earlier in clinical trials, providing significant cost savings. A cancer’s progression or remission can now be determined by an additional qualified criterion. As a result, compounds that are ineffectual may be identified earlier, reducing the expense of studies and trials. Similarly, costly treatments for patients may be recognized earlier if they are shown to be ineffective.

Definiens LymphExpert Version 2.0 by Definiens LymphExpert is a core application of the Definiens Oncology Suite and has been submitted for CE-mark approval in the European Market.

For more information: www.definiens.com

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