News | January 10, 2008

Imaging Helps Heart Modelling Research

January 11, 2008 - Imaging technologies are helping heart modellers overcome the dilemma of proving that the models really are an accurate representation of the real human heart, as demonstrated in a workshop held recently by the European Science Foundation (ESF).

Computerized in-silico models simulate the real heart and enable possible drugs and therapies to be tested without risk to people.
However, in order to create a realistic model, you need accurate and extensive data from real hearts for calibration.

“Validation of the models is very important, and was raised at the workshop,” said Blanca Rodriguez, scientific coordinator of the ESF workshop, and senior cardiac researcher at Oxford University, Europe’s leading center for cardiac modelling. “One of the problems has been that it is much easier to get experimental data from animals than humans.”

Progress in imaging techniques allows researchers to observe cardiac activity externally without the need for invasive probes. “We are now getting data at very high resolutions and that allows us to model things in more detail, with greatly improved anatomy and structure,” said Rodriguez.

One of the most important diseases being modelled is myocardial ischemia. Studying stem cell therapy to regenerate heart muscle destroyed by disease requires careful testing to eliminate possibly dangerous side effects, such as cancer and disruption of normal heart rhythms, leading to arrhythmia or irregular heart beats. Heart models “could be used to model stem cells’ behavior, and see how they are incorporated into the heart,” said Rodriguez.

Rodriguez recommends that researchers create a standard and robust software infrastructure for sharing heart models and associated data, and to define exactly how to calibrate the models more effectively from experimental data.

For more information: www.esf.org

Related Content

ASNC and SNMMI Release Joint Document on Diagnosis, Treatment of Cardiac Sarcoidosis
News | Cardiac Imaging | August 18, 2017
August 18, 2017 — The American Society of Nuclear Cardiology (ASNC) has released a joint expert consensus document wi
X-ray of a knee replacement. CMS may change reimbursements for joint and knee replacements. Patient Marilyn Fornell.

CMS may change how it reimburses for knee replacements and said it may eliminate bundled payments for acute cardiac care.

Feature | Business | August 16, 2017 | Dave Fornell
August 16, 2017 — The Centers for Medicare and Medicaid Services (CMS) announced a proposed rule to reduce the number
CMS considers eliminating or changing bundled payments for orthopedic and knee replacement imaging. Photo by Vital Images

CMS is considering elimination or changing bundled payments for knee replacements. 

News | August 14, 2017 | Dave Fornell
...
CDN to Integrate Advanced Cardiac Imaging Tools From DiA Imaging Analysis
Technology | Advanced Visualization | August 10, 2017
August 10, 2017 — CDN recently announced a new partnership agreement with DiA Imaging Analysis Ltd., makers of next-g
Four Blue Cross Blue Shield Companies Issue Positive Medical Policies on HeartFlow FFRct Analysis
News | Computed Tomography (CT) | August 09, 2017
HeartFlow Inc. announced that four Blue Cross Blue Shield companies have each issued a positive medical policy for the...
Sponsored Content | Videos | CT Angiography (CTA) | July 21, 2017
DAIC and ITN Editor Dave Fornell discusses some of the most innovative new computed tomography (CT) technology and tr
Sponsored Content | Videos | CT Angiography (CTA) | July 19, 2017
Matthew Budoff, M.D., FACC, professor of medicine, David Geffen School of Medicine at UCLA, endowed chair of preventi
Sponsored Content | Videos | CT Angiography (CTA) | July 19, 2017
Leslee Shaw, Ph.D., director of clinical research and professor of medicine at Emory University, Atlanta, and past-pr
Low Doses of Radiation Could Harm Cardiovascular Health
News | Radiation Dose Management | July 17, 2017
Ionizing radiation, such as X-rays, has a harmful effect on the cardiovascular system even at doses equivalent to...
Overlay Init