News | August 03, 2009

First Skin Cancer Patients Treated Using Miniaturized X-ray

August 3, 2009 – Xoft Inc. said it has expanded the treatment capabilities of the Axxent Electronic Brachytherapy, eBx, System with the launch of a multicenter skin cancer trial to further prove the safety and feasibility for the treatment of non-melanoma skin cancers at the 51st Annual American Association of Physicists in Medicine (AAPM) Meeting.
The company also announced that the first skin cancer patients were recently treated using the FDA-cleared Axxent System, which has been available for the treatment of early stage breast cancer since 2005 and endometrial cancer since 2008.

“I am very excited to be the principal investigator for the first clinical study utilizing Xoft’s Electronic Brachytherapy for surface treatment of non-melanoma skin cancers,” said Ajay Bhatnagar, M.D., of Cancer Treatment Services of Arizona. “Since skin cancers usually present on areas exposed to the sun frequently, such as the face, head and neck, we have to consider both the eradication of the cancer as well as cosmetic outcomes when determining the best treatment option for the patient.”
“Radiation therapy has been a common modality for the treatment of non-melanomatous skin cancers especially for elderly patients with lesions in cosmetically sensitive areas. There is also a wide variability in the radiation treatment for skin cancer in terms of the different radiation modalities and dose fractionation schemes. That is why I believe this is a particularly important prospective study which should help us gain a better understanding of the use of radiation therapy, specifically electronic brachytherapy, for the primary treatment of non-melanomatous skin cancer,” added Dr. Bhatnagar.
The prospective study is designed to gather data to enable physicians to develop guidelines for treating skin cancer patients with Electronic Brachytherapy that will result in the best patient outcomes. Treatment options for non-melanoma skin cancer typically include several types of surgery, topical treatments and radiation therapy. The location of the cancer and the extent of the disease impacts which treatment option is best for each patient. Whether in combination with surgery or as a stand-alone treatment, Electronic Brachytherapy will enable clinicians to administer radiation therapy without the use of a radioactive isotope and in clinical settings where a shielded vault is not needed. As the radiation oncologist can remain at the patient’s side during treatment, the entire procedure can be visually monitored for the accurate delivery of treatment to the cancer site.
“Given my recent clinical experience with High Dose Rate brachytherapy with an Ir-192 remote afterloader using the surface applicators for my skin cancer patients, I was particularly intrigued with the ability of electronic brachytherapy to provide a similar and possibly superior clinical outcome in a more patient friendly environment. The ability to treat with little impact on surrounding normal tissues should allow for an excellent cosmetic outcome as well as a high chance of treatment success with skin cancer. Therefore, this study is extremely vital and will help our field gain more credibility in the world of skin cancer including the dermatologists,” said Dr. Bhatnagar.
Available for treatment of early stage breast cancer, endometrial cancer, and skin cancer, the Axxent eBx System is also FDA-cleared for IORT (intra-operative radiation therapy). As a platform technology, the Axxent System is designed to deliver non-radioactive therapy directly to cancer sites with minimal radiation exposure to surrounding healthy tissue. Utilizing a proprietary miniaturized X-ray source and robotic controller, the system can be used to deliver radiation in minimally shielded therapeutic settings. Treatment can be performed without the need for a shielded room, allowing the radiation oncologist and other medical personnel to be present during treatment delivery and minimizing patient anxiety.
For more information: www.xoftinc.com

Related Content

Clinical Data Supports Use of Xoft System for Endometrial Cancer
News | Brachytherapy Systems | August 03, 2017
Researchers presented clinical data supporting use of the Xoft Axxent Electronic Brachytherapy (eBx) System for the...
Australia's Monash Cancer Centre Treats First Early-Stage Breast Cancer Patient With Xoft System
News | Brachytherapy Systems, Women's Healthcare | May 01, 2017
iCAD Inc. announced the first early-stage breast cancer patient was treated in Australia with intraoperative radiation...
New Clinical Data on Xoft System Presented at American Brachytherapy Society Annual Meeting
News | Brachytherapy Systems, Women's Healthcare | April 20, 2017
iCAD Inc. announced that updated clinical data on the use of intraoperative radiation therapy (IORT) using the Xoft...
Concure Oncology, Breast Microseed Treatment, one day, low-dose rate brachytherapy, LDR
Technology | Brachytherapy Systems, Women's Healthcare | May 12, 2016
Concure Oncology/Breast Microseed Inc. announced the launch of its one-time, one-hour radiation treatment option for...
News | Brachytherapy Systems, Women's Healthcare | April 20, 2016
Cianna Medical Inc. announced new clinical data evaluating the Savi Scout breast localization and surgical guidance...
Gamma pro, kubtec
News | Breast Imaging | November 04, 2015
Kubtec announced the launch of the Gamma-Pro Node and Seed Location System for use in breast seed location and sentin
iCAD, Xoft Axxent, electronic brachytherapy, eBx, clinical studies, ASTRO 2015, radiation therapy

Xoft Axxent image courtesy of iCAD Inc.

News | Brachytherapy Systems | October 21, 2015
iCAD Inc. presented updated clinical data, hosted in-booth clinician presentations and showcased the latest in...
APBI, accelerated partial breast irradiation, multicatheter brachytherapy, breast conserving surgery, whole breast irradiation, WBI, ASTRO 2015
News | Brachytherapy Systems, Women's Healthcare | October 19, 2015
For some early-stage breast cancer patients, accelerated partial breast irradiation (APBI) using multicatheter...
Theragenics, Advanced Radiation Therapy LLC, AccuBoost, early stage breast cancer, brachytherapy
News | Brachytherapy Systems, Women's Healthcare | August 07, 2015
Theragenics Corp. has reached an agreement with Advanced Radiation Therapy LLC to distribute the AccuBoost technology...
Cianna Medical, SAVI Scout, breast surgical guidance system

Photo courtesy of Cianna Medical

Technology | December 16, 2014
Cianna Medical Inc. received U.S. Food and Drug Administration (FDA) clearance for the SAVI Scout surgical guidance...
Overlay Init