August 3, 2009 – Xoft Inc. said it has expanded the treatment capabilities of the Axxent Electronic Brachytherapy, eBx, System with the launch of a multicenter skin cancer trial to further prove the safety and feasibility for the treatment of non-melanoma skin cancers at the 51st Annual American Association of Physicists in Medicine (AAPM) Meeting.
The company also announced that the first skin cancer patients were recently treated using the FDA-cleared Axxent System, which has been available for the treatment of early stage breast cancer since 2005 and endometrial cancer since 2008.

“I am very excited to be the principal investigator for the first clinical study utilizing Xoft’s Electronic Brachytherapy for surface treatment of non-melanoma skin cancers,” said Ajay Bhatnagar, M.D., of Cancer Treatment Services of Arizona. “Since skin cancers usually present on areas exposed to the sun frequently, such as the face, head and neck, we have to consider both the eradication of the cancer as well as cosmetic outcomes when determining the best treatment option for the patient.”
“Radiation therapy has been a common modality for the treatment of non-melanomatous skin cancers especially for elderly patients with lesions in cosmetically sensitive areas. There is also a wide variability in the radiation treatment for skin cancer in terms of the different radiation modalities and dose fractionation schemes. That is why I believe this is a particularly important prospective study which should help us gain a better understanding of the use of radiation therapy, specifically electronic brachytherapy, for the primary treatment of non-melanomatous skin cancer,” added Dr. Bhatnagar.
The prospective study is designed to gather data to enable physicians to develop guidelines for treating skin cancer patients with Electronic Brachytherapy that will result in the best patient outcomes. Treatment options for non-melanoma skin cancer typically include several types of surgery, topical treatments and radiation therapy. The location of the cancer and the extent of the disease impacts which treatment option is best for each patient. Whether in combination with surgery or as a stand-alone treatment, Electronic Brachytherapy will enable clinicians to administer radiation therapy without the use of a radioactive isotope and in clinical settings where a shielded vault is not needed. As the radiation oncologist can remain at the patient’s side during treatment, the entire procedure can be visually monitored for the accurate delivery of treatment to the cancer site.
“Given my recent clinical experience with High Dose Rate brachytherapy with an Ir-192 remote afterloader using the surface applicators for my skin cancer patients, I was particularly intrigued with the ability of electronic brachytherapy to provide a similar and possibly superior clinical outcome in a more patient friendly environment. The ability to treat with little impact on surrounding normal tissues should allow for an excellent cosmetic outcome as well as a high chance of treatment success with skin cancer. Therefore, this study is extremely vital and will help our field gain more credibility in the world of skin cancer including the dermatologists,” said Dr. Bhatnagar.
Available for treatment of early stage breast cancer, endometrial cancer, and skin cancer, the Axxent eBx System is also FDA-cleared for IORT (intra-operative radiation therapy). As a platform technology, the Axxent System is designed to deliver non-radioactive therapy directly to cancer sites with minimal radiation exposure to surrounding healthy tissue. Utilizing a proprietary miniaturized X-ray source and robotic controller, the system can be used to deliver radiation in minimally shielded therapeutic settings. Treatment can be performed without the need for a shielded room, allowing the radiation oncologist and other medical personnel to be present during treatment delivery and minimizing patient anxiety.
For more information: www.xoftinc.com

Related Content

360 Photos | Brachytherapy Systems

This is a 360 degree view inside one of the brachytherapy treatment rooms at Northwestern Medicine's center in ...

Time October 28, 2021
arrow
News | Brachytherapy Systems

August 31, 2021 — iCAD, Inc., a global medical technology leader providing innovative cancer detection and therapy ...

Time August 31, 2021
arrow
News | Radiation Oncology

June 2, 2021 — A breast cancer therapy that requires just one shot of radiotherapy is as effective as traditional ...

Time June 02, 2021
arrow
News | Brachytherapy Systems, Women's Healthcare

May 19, 2021 — A new study finds that brachytherapy, a common procedure that delivers radiation directly to cancer cells ...

Time May 19, 2021
arrow
News | Brachytherapy Systems

October 26, 2020 — iCAD, Inc. announced the Company will showcase the expanded platform for the Xoft Axxent Electronic ...

Time October 26, 2020
arrow
News | Brachytherapy Systems, Women's Healthcare

September 8, 2020 — Advanced Radiation Therapy has completed the installation of the AccuBoost Digital platform at the ...

Time September 08, 2020
arrow
News | Brachytherapy Systems, Women's Healthcare

At the 2019 American Society for Radiation Oncology (ASTRO) annual meeting, Sept. 15-18 in Chicago, Advanced Radiation Therapy, makers of AccuBoost, announced the latest upgrades to the AccuBoost Digital platform. AccuBoost Digital leverages the Planmed Clarity digital mammography system to provide doctors with real-time image-guidance and targeting confidence in the delivery of accelerated partial breast irradiation (APBI) in patients opting for breast conserving therapy (BCT). These upgrades improve the treatment workflow, patient experience and user interface. By design, this non-invasive breast brachytherapy (NIBB) technique is 100 percent adaptive as each treatment fraction is assessed independently and is ideal for the challenges that APBI treatments can present.

Time October 23, 2019
arrow
Videos | Radiation Therapy

ITN Associate Editor Jeff Zagoudis speaks with Christy Kesslering, M.D., medical director of radiation oncology at the ...

Time February 21, 2019
arrow
News | Brachytherapy Systems, Women's Healthcare

Breast cancer recurrence rates of patients treated with intraoperative radiation therapy (IORT) using the Xoft Axxent Electronic Brachytherapy (eBx) System were comparable to those seen in the TARGIT-A and ELIOT trials, according to new results. The results, published in the Annals of Surgical Oncology, came from a long-term study conducted at Hoag Memorial Hospital Presbyterian in Newport Beach, Calif.

Time January 07, 2019
arrow
News | Women's Health

Disposable device manufacturer Merit Medical Systems Inc. announced the closing of a definitive merger agreement to acquire Cianna Medical Inc., headquartered in Aliso Viejo, Calif. The deal structure includes an upfront payment of $135 million with potential earn-out payments of an additional $15 million for achievement of supply chain and scalability metrics, and up to an additional $50 million for achievement of sales milestones.

Time November 14, 2018
arrow
Subscribe Now