News | Mammography | October 16, 2015

Dutch Study Reaffirms Importance of Early Detection for Breast Cancer

Findings demonstrate size of tumor, involvement of lymph nodes directly impact overall long-term survival

breast cancer, early detection, BMJ, Dutch study, Elaine Schattner, lymph nodes, tumor size

October 14, 2015 — Findings from a new population-based study in the Netherlands appear to reaffirm that early detection of breast cancer positively impacts long-term patient survival.

The study — based out of Erasmus University Medical Centre, the Netherlands Comprehensive Cancer Organization and the University of Twente and published in the BMJ — retrospectively looked at the cases of 174,000 Dutch women. The population was broken into two large cohorts: women diagnosed with breast cancer between 1999 and 2005 (80,228 women, median age 59) and women diagnosed 2006-2012 (93,569 women, median age 60). According to study authors, the two cohorts were selected due to significant changes in the screening guidelines in 2005.

Elaine Schattner, M.D., in a piece on the study for Forbes, said there are two key takeaways from the results:

  • Overall survival was significantly shorter for women whose breast cancer had spread to the lymph nodes; and
  • Larger, invasive tumors had a significantly greater impact on long-term survival than smaller invasive cancers.

Schattner also noted that data from the period of 2006-2012 indicated more early-stage diagnoses and low-grade tumors, increases in lumpectomy and increased use of medicines including hormonal treatments.

Study authors note that the Netherlands instituted a national biennial mammography screening program in 1989; the program was initially targeted for all women age 50-69 and was expanded to included women age 71-75 in 1998.

The Dutch study findings go against the modern view, held in some circles, that early detection has little value. According to Schattner, this view is largely based on a 2012 study in the New England Journal of Medicine that attributed improvements in breast cancer survival rates to better treatment options as opposed to mammography screening.

For more information:

Related Content

Theraclion to Launch Metastatic Breast Cancer Trial Combining Echotherapy and Immunotherapy
News | Focused Ultrasound Therapy | September 18, 2017
September 18, 2017 — Theraclion and co-lead investigator David Brenin, M.D., from the University of Virginia School o Debuts  Spanish Language Video  About Dense Breasts
News | Breast Density | September 12, 2017
Breast cancer risks associated with breast density are the subject of a new Spanish language video launched recently by...
Asian Study Underlines Potential Value of Pressure-Guided Mammography
News | Mammography | September 11, 2017
Sigmascreening recently announced that a study of in total 15,898 in digital mammograms from 3,772 Asian women...
Delphinus Enrolls First Patient in Discover Breast Ultrasound Clinical Project
News | Ultrasound Womens Healthcare | September 08, 2017
September 8, 2017 — Delphinus Medical Technologies Inc.
Breast imaging X-ray mammogram showing a breast tumor. Photo courtesy of Monthian Ritchan-Ad

Photo courtesy of Monthian Ritchan-Ad

Feature | Breast Density | September 08, 2017 | By Roy Prager, M.D.
While mammograms play a vital role in efforts to identify breast cancer, they can present some challenges in women with...
FDA Clears Senographe Pristina Mammography System With Patient-Assisted Compression
Technology | Mammography | September 05, 2017
The U.S. Food and Drug Administration (FDA) cleared GE Healthcare’s Senographe Pristina with Self-Compression, the...
FDA Releases Six-Month Inspection Data From EQUIP Mammography Quality Initiative
News | Mammography | September 01, 2017
September 1, 2017 — The Division of Mammography Quality Standards (DMQS) of the U.S.
Hologic Announces Availability of Brevera Breast Biopsy System With CorLumina Imaging Technology
Technology | Breast Biopsy Systems | August 31, 2017
Hologic Inc. announced U.S. commercial availability of the Brevera breast biopsy system with CorLumina imaging...
China FDA Approves Xoft Axxent Balloon Applicators for Early-Stage Breast Cancer
News | Brachytherapy Systems, Women's Healthcare | August 30, 2017
iCAD Inc. announced that the company’s Xoft Axxent balloon applicators have received approval from the China Food...
Top list of stories, article, videos for breast imaging.
Feature | Breast Imaging | August 30, 2017 | Dave Fornell
August 30, 2017 — This is a list of the top breast imaging content so far for 2017.
Overlay Init