News | October 02, 2009

CMR Evaluation of HF to Grow Substantially in Coming Years

October 2, 2009 – Cardiovascular magnetic resonance (CMR) in the evaluation of patients with heart failure (HF) “will expand substantially in the coming years,” according to the authors of a study published in October 2009 issue of the Journal of American College of Cardiology.

In the study, The Role of Cardiovascular Magnetic Resonance Imaging in Heart Failure, the authors emphasize the efficacy of CMR in assessing myocardial anatomy, regional and global function, and viability, and assessment of perfusion and acute tissue injury, and notes that CMR often “reveals the underlying etiology of heart failure, and its high measurement accuracy makes it an ideal technique for monitoring disease progression and the effects of treatment.” They add that increasing evidence that “the prognostic value of CMR-derived parameters in heart failure is rapidly emerging.”

“We predict that most patients with HF will eventually undergo CMR imaging as part of the diagnostic workup and to guide management and stratify risk,” the authors wrote.

The researchers listed the proposed indications for the use of CMR in HF patients that are likely to further expand in the near future. These indications include:
- Serial assessment of biventricular structure, size, and function (anatomy, LV/RV volumes, global and regional systolic function, mass)
- Evaluation of native and prosthetic cardiac valves (planimetry of stenotic disease, estimation of peak stenotic velocities and gradients, quantification of regurgitant disease)
- Evaluation of cardiac masses, differentiation between tumor and thrombus
- Evaluation of great vessels and pulmonary veins
- Determination of the location and extent of acute (including no-reflow regions) and chronic myocardial necrosis
Viability assessment before revascularization (LGE or low-dose dobutamine)
- Determination of the area at risk in patients with acute myocardial infarction and the salvageable area post-revascularization with percutaneous coronary intervention
- Identification of the presence and quantification of the extent of inducible ischemia (vasodilator perfusion or high-dose dobutamine stress CMR)
- Evaluation of suspected anomalous coronary origins (MR coronary angiography)
- Differentiation of ischemic versus nonischemic cardiomyopathy
- Evaluation of myocarditis
- Evaluation of specific cardiomyopathies (in vivo tissue characterization)
- Assessment of mechanical dyssynchrony before resynchronization therapy
- Patients with technically limited images from echocardiogram
- Discordant information that is clinically significant from prior tests

Plus, in their conclusion, the researchers anticipate that “improvement in software and hardware will further shorten scan times and allow the use of real-time imaging with better spatial and temporal resolution. New CMR techniques aiming at the identification and quantification of diffuse fibrosis will further improve the in vivo assessment of myocardial pathology.”

They pointed to other growth for CMR that include: novel CMR contrast agents, stem cell therapy monitored by CMR, interventional CMR to guide therapeutic procedures, and finally MR spectroscopy to assess metabolic changes in the failing heart and monitoring of the response to novel forms of metabolic therapy.

Reference: Theodoros D. Karamitsos, M.D., Ph.D.,* Jane M. Francis, DCC(R), DNM,* Saul Myerson, M.D.,* Joseph B. Selvanayagam, MBBS, DPHIL,† Stefan Neubauer, M.D.,* Oxford, United Kingdom; and Adelaide, Australia. The Role of Cardiovascular Magnetic Resonance Imaging in Heart Failure. J Am Coll Cardiol, 2009; 54:1407-1424, doi:10.1016/j.jacc.2009.04.094

For more information: www.ocmr.ox.ac.uk

Related Content

 Many patients with severe coronavirus disease 2019 (COVID-19) remain unresponsive after surviving critical illness. Investigators led by a team at Massachusetts General Hospital (MGH) now describe a patient with severe COVID-19 who, despite prolonged unresponsiveness and structural brain abnormalities, demonstrated functionally intact brain connections and weeks later he recovered the ability to follow commands

Getty Images

News | Coronavirus (COVID-19) | July 08, 2020
July 8, 2020 — Many patients with severe coronavirus disease 2019 (...
A patient implanted with the Axonics System can undergo MRI examinations safely with radio frequency (RF) Transmit Body or Head Coil under the conditions outlined in the Axonics MRI Conditional Guidelines.

A patient implanted with the Axonics System can undergo MRI examinations safely with radio frequency (RF) Transmit Body or Head Coil under the conditions outlined in the Axonics MRI Conditional Guidelines.

News | Magnetic Resonance Imaging (MRI) | July 02, 2020
July 2, 2020 — Axonics Modulation Technologies, Inc., a medical technology company that has developed and is commerci
This data represents wave 2 of a QuickPoLL survey conducted in partnership with an imagePRO panel created by The MarkeTech Group (TMTG), regarding the effects of COVID-19 on their business

Getty Images

Feature | Coronavirus (COVID-19) | July 01, 2020 | By Melinda Taschetta-Millane
Researchers reviewed results of prostate biopsies on over 3,400 men who had targets identified on prostate MRI and found that the positive predictive value of the test for prostate cancer was highly variable at different sites
News | Prostate Cancer | July 01, 2020
July 1, 2020 — Prostate MRI is an emerging technology used to identify and guide treatment for...
R2* maps of healthy control participants and participants with Alzheimer disease. R2* maps are windowed between 10 and 50 sec21. Differences in iron concentration in basal ganglia are too small to allow visual separation between patients with Alzheimer disease and control participants, and iron levels strongly depend on anatomic structure and subject age. Image courtesy of Radiological Society of North America

R2* maps of healthy control participants and participants with Alzheimer disease. R2* maps are windowed between 10 and 50 sec21. Differences in iron concentration in basal ganglia are too small to allow visual separation between patients with Alzheimer disease and control participants, and iron levels strongly depend on anatomic structure and subject age. Image courtesy of Radiological Society of North America

News | Magnetic Resonance Imaging (MRI) | July 01, 2020
July 1, 2020 — Researchers using magnetic...
In new QuickPoLL survey on imaging during the pandemic, responses were tallied from around 170 radiology administrators and business managers, who are part of an imagePRO panel created by The MarkeTech Group (TMTG), regarding the effects of COVID-19 on their business. TMTG is a research firm specializing in the medical device, healthcare and pharmaceutical industries.
Feature | Coronavirus (COVID-19) | June 30, 2020 | By Melinda Taschetta-Millane
Cardiac MR can offer data above and beyond anatomical imaging, which is the main reason why this system was installed at Baylor Scott White Heart Hospital in Dallas. The system is a dedicated heart MRI scanner.

Cardiac MR can offer data above and beyond anatomical imaging, which is the main reason why this system was installed at Baylor Scott White Heart Hospital in Dallas. The system is a dedicated heart MRI scanner.

News | Pediatric Imaging | June 29, 2020
June 29, 2020 — A type of smart magnetic r...
This image of DCE-MRI reveals persistent blood brain barrier disorder in American football players. Using brain imaging techniques and analytical methods, researchers can determine whether football players have CTE by measuring leakage of the blood-brain barrier. Image courtesy of Ben-Gurion University

This image of DCE-MRI reveals persistent blood brain barrier disorder in American football players. Using brain imaging techniques and analytical methods, researchers can determine whether football players have CTE by measuring leakage of the blood-brain barrier. Image courtesy of Ben-Gurion University

News | Magnetic Resonance Imaging (MRI) | June 22, 2020
June 22, 2020 — Chronic traumatic encephalopathy (CTE), a neurodegenerative disease caused by repeated...
Axial FLAIR in four different COVID-19 patients. A) 58-year old man with impaired consciousness: FLAIR hyperintensities located in the left medial temporal lobe. B) 66-year old man with impaired consciousness: FLAIR ovoid hyperintense lesion located in the central part of the splenium of the corpus callosum. C) 71-year old woman with pathological wakefulness after sedation: extensive and confluent supratentorial white matter FLAIR hyperintensities (arrows). Association with leptomeningeal enhancement (stars

Axial FLAIR in four different COVID-19 patients. A) 58-year old man with impaired consciousness: FLAIR hyperintensities located in the left medial temporal lobe. B) 66-year old man with impaired consciousness: FLAIR ovoid hyperintense lesion located in the central part of the splenium of the corpus callosum. C) 71-year old woman with pathological wakefulness after sedation: extensive and confluent supratentorial white matter FLAIR hyperintensities (arrows). Association with leptomeningeal enhancement (stars) D) 61-year old man with confusion: hyperintense lesions involving both middle cerebellar peduncles. Image courtesy of the journal Radiology

News | Coronavirus (COVID-19) | June 16, 2020
June 16, 2020 — Current data on central nervous system (CNS) involvement in...