Technology | November 09, 2008

Automated Coronary Calciums Scoring Detects Plaques Not Found by Agatston Methods

CoronaryScore is a software program for detecting and scoring calcifications in the coronary arteries developed by the medical imaging company Image Analysis Inc.

Study results show technology can detect and score small plaques that are missed by current Agatston-based methods. In an early clinical study, it was found 25 percent of patients with a zero Agatston score in fact had small calcifications in the coronaries detected and scored by the Image Analysis software, the company said.

MDCT coronary artery calcium (CAC) scoring has become important in risk categorization for myocardial infarction and as a screening and staging test for CT angiography. But the technology has traditionally been plagued by a 2 to 5% false negative error for hard coronary events and somewhat lower for significant stenosis.

Using the software images are calibrated with a small cross-sectional calcium hydroxyappatite phantom that is scanned simultaneously with the patient. In addition, it uses the patient’s own blood pool/muscle to standardize the scans in a unique hybrid calibration program. Two scoring thresholds are automatically computed by the software in background mode for the specific patient, scanner, and even specific scan. The thresholds are determined from histogram analysis using statistical computations and variable connectivity criteria based on voxel size and image noise.

The software does not come with a manual, as the company feels it is easy to use and has a system of imbedded, animated help files.

To run the CoronaryScore software, the operator clicks at the origin of the left main artery and then the bifurcation of the LAD/Circ. Then the software automatically segments the heart; performs hybrid calibration; computes the two thresholds and plaque definition criteria; detects the plaques and identifies each to its coronary artery; calculates the calibrated mass score for each plaque, artery, and for the patient; calculates the Agatston and volume scores, either calibrated or not; and the mass plaques are sorted by size and displayed in a distribution graph. The plaque maps and scoring operation allows toggle on/off of the Agatston score and map and toggle on/off of plaque highlights for either Agatston or mass scores.

The automated software provides automated plaque detection and scoring (even with small voxel images) without operator interaction. The software displays them in a viewable 3D plaque map with each plaque shown in three planes and referenced to its exact 3D location in the volume data set. The manufacturer says the automation allows a 160-slice image set to be scored in under three seconds.

November 2008

Related Content

Siemens Healthineers Announces First U.S. Install of Somatom go.Top CT
News | Computed Tomography (CT) | September 17, 2018
September 17, 2018 — The Ohio State University Wexner Medical Center in Columbus recently became the first healthcare
The Siemens Biograph Vision PET-CT system was released in mid-2018.

The Siemens Biograph Vision PET-CT system was released in mid-2018.

Feature | Nuclear Imaging | September 07, 2018 | By Dave Fornell
Nuclear imaging technology for both single photon emission computed tomography (SPECT) and positron emission tomography...
Rapid Cardiac MRI Technique May Cut Costs, Boost Care in Developing World
News | Magnetic Resonance Imaging (MRI) | August 29, 2018
A newly developed rapid imaging protocol quickly and cheaply diagnosed heart ailments in patients in Peru, according to...
Philips Launches Epiq CVx and CVxi Cardiovascular Ultrasound Systems
Technology | Cardiovascular Ultrasound | August 22, 2018
Philips recently announced the introduction of the Epiq CVx cardiovascular ultrasound system. Built on the Epiq...
Videos | Magnetic Resonance Imaging (MRI) | August 13, 2018
Haojie Wang, M.D., director of advanced cardiovascular MRI and a member of the heart valve clinic at Baylor Scott Whi
Cardiac Imaging Reveals Roots of Preeclampsia Damage in Pregnant Women
News | Women's Health | August 07, 2018
Johns Hopkins researchers say a heart imaging study of scores of pregnant women with the most severe and dangerous form...
Videos | Computed Tomography (CT) | July 25, 2018
A discussion with Patricia Dickson, LRT(CT), director of imaging and outpatient services, Capital Cardiology Associat
Researchers Trace Parkinson’s Damage in the Heart
News | PET Imaging | July 17, 2018
A new way to examine stress and inflammation in the heart will help Parkinson’s researchers test new therapies and...
Zebra Medical Vision Announces FDA 510(k) Clearance of Coronary Calcium Algorithm
Technology | Computed Tomography (CT) | July 12, 2018
Zebra Medical Vision has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) for its Coronary...
Overlay Init