Feature | September 04, 2014 | Greg Freiherr

Tomo Draws the Line In Breast Screening

Intelerad

Westerners want neatly drawn lines, simple demarcations, absolutes. In some cases, the lines are apparent. Others are not. Continents are easy to distinguish visibly from oceans. The boundaries between countries are not.

If drawing such differences depends on physical evidence, shouldn’t a clear distinction be possible between diseased and healthy tissue? This paradox is obvious when screening for breast cancer. Improving the means for seeing early signs should do the trick. Breast tomosynthesis may be it.

On June 25, JAMA (Journal of the American Medical Association) published research indicating that the addition of 3-D imaging — breast tomosynthesis — to mammography results in the discovery of more cancers than the use of 2-D digital mammography alone — a 41 percent increase in the detection of invasive breast cancers and a 29 percent increase in the detection of all breast cancers.

The data is hardly surprising. The U.S. Food and Drug Administration (FDA) approved the sale of tomo devices for breast cancer screening in 2011 because of similar research findings. The JAMA paper underscores this, while shining a light on one of the most appealing side benefits — a reduction in false positives and consequent reduction of recall rates. Before the publication of this paper, this positive effect had been largely anecdotal.

Data acquired at 13 U.S. centers performing 454,850 screening exams (61 percent of which involved only 2-D digital mammography for comparison) found that the addition of tomo dropped the recall rate from 107 to 91 per 1,000 screening exams — a 15 percent decrease. This translates to 16 fewer recalls per 1,000 screening exams. 

Callbacks have always been a problem in mammography. They are a source of worry, added discomfort, patient complaints and unnecessary cost. Moreover, they call into question the credibility of exams, whose use depends on women’s belief in their value.

The new study addresses this concern and another often attributed to breast cancer screening — the finding of cancers that don’t need to be treated. The latter was demonstrated by the 41 percent increase in the detection of invasive breast cancers; the former by a double-digit reduction in the recall rate. 

It’s hard to overestimate the importance of these findings. Screening mammography exposes women with no known sign of disease to ionizing radiation, which itself can cause cancer. As such, women deserve the greatest possible assurance that the exam they undergo is done with the least chance of being wrong.

The JAMA study documents that the routine use of tomosynthesis in breast cancer screening does exactly this, providing women the reason to believe that modern mammography truly can save lives. 

Related Content

Clinical Data Supports Use of Xoft System for Endometrial Cancer
News | Brachytherapy Systems | August 03, 2017
Researchers presented clinical data supporting use of the Xoft Axxent Electronic Brachytherapy (eBx) System for the...
The ASPIRE Cristalle FFDM system with DBT combines Fujifilm’s state-of-the-art hexagonal close pattern (HCP) detector design, advanced image processing and image acquisition workflow
News | Women's Health | August 01, 2017
Fujifilm Medical Systems U.S.A., Inc. announced that The Mammography Center of Monterey, an ACR-accredited breast...
Sponsored Content | Videos | Breast Imaging | July 28, 2017
Nancy Cappello, Ph.D., executive director and founder of Are You Dense Inc. and Are You Dense Advocacy, explains how
Radiotherapy Prior to Surgery Reduces Secondary Tumor Risk in Early-Stage Breast Cancer Patients
News | Radiation Therapy | July 24, 2017
Moffitt Cancer Center researchers launched a first-of-its-kind study comparing the long-term benefits of radiation...
Kubtec Launches New Website For Digital Imaging and Irradiation Products
News | Digital Radiography (DR) | July 20, 2017
Kubtec announced the launch a new website focused on the applications of digital X-ray imaging and irradiation for...
Volpara Solutions to Showcase Volpara Enterprise DDP Software at AHRA 2017
News | Mammography | July 11, 2017
Volpara Solutions Inc. will showcase its new Volpara Enterprise DDP software at the Association for Medical Imaging...
Fujifilm Showcases Digital Radiography, Mammography Innovations at AHRA 2017
News | Digital Radiography (DR) | July 06, 2017
Fujifilm Medical Systems U.S.A. Inc. will present its comprehensive portfolio of digital radiography (DR) and...
Feature | Breast Density | July 05, 2017 | By Nancy M. Cappello, Ph.D.
Two decades of research on the masking risk of dense breast tissue by mammography screening is indisputable. As the...
Solis Mammography Ranks No. 19 in Dallas Business Journal’s Middle Market 50
News | Mammography | June 30, 2017
June 30, 2017 — Solis Mammography was named the 19th fastest-growing, middle-market company in North Texas by the
GE Healthcare Announces First U.S. Installation of Senographe Pristina Mammography System
News | Mammography | June 29, 2017
GE Healthcare has collaborated with Boca Raton Regional Hospital (Boca Raton, Fla.) to bring a more comfortable...
Overlay Init